2015 Conference

Opening ceremony

New ASPEC - GERPAC guide Qualification & Maintenance of isolators S. Vandriessche ASPEC, France

Oral preparations and prepared oral unit dose

Reconditioning solid oral doses of hazardous drugs: Quebec experience J.F. Bussières B.Pharm., M.Sc., FCSHP, MBA, chef, Département de pharmacie et Unité de recherche en pratique pharmaceutique, CHU Sainte-Justine,
Professeur adjoint de clinique, Faculté de pharmacie, Université de Montréal,
Montréal, Québec, Canada Medicine stability in multi-compartment compliance aids J. Gilmartin C W Maplethorpe Postdoctoral Fellow for Pharmaceutical Education and Research
University College London School of Pharmacy
London, UK

Microbial contamination

Microbiological validation of a fully automated cytotoxic preparation system compared to manual preparation Irene Krämer Department of Pharmacy, University Medical Center,
Johannes Gutenberg-University, Langenbeckstraße 1,
55131 Mainz, Germany Hot topic in Microbiology - Isolator Technology - What are the challenges of the Pharmaceutical Industry for the future? B. Ramond Senior Microbiology Expert,
Sanofi, Paris, France A new international journal dedicated to hospital pharmacy: "Pharmaceutical Technology in Hospital Pharmacy" F. Lagarce INSERM U 646,
CHU Angers, France

Chemical contaminations

Surface contamination results of a multicenter European study P. Sessink¹, S. Crauste-Manciet² 1 Exposure Control Sweden AB
2 Bordeaux University Hospital - Bordeaux University Pilot study of biological monitoring of four antineoplastic drugs among Canadian healthcare workers C. Poupeau¹, C. Tanguay², C. Plante³, N.J. Caron⁴, JF. Bussières⁵ 1 D.Pharm. candidate, Research assistant, Pharmacy Practice Research Unit, CHU Sainte-Justine, Montréal, Québec, Canada
2 B.Sc., M.Sc., Coordinator, Pharmacy Practice Research Unit, CHU Sainte-Justine, Montréal, Québec, Canada
3 Inf, conseillère en soins infirmiers, CHU Sainte-Justine, Montréal, Québec, Canada
4 Ph.D, Centre de toxicologie du Québec, Institut national de santé publique du Québec, Québec, Canada
5 B.Pharm., M.Sc., FCSHP, MBA, chef, Département de pharmacie et Unité de recherche en pratique pharmaceutique, CHU Sainte-Justine, professeur adjoint de clinique, Faculté de pharmacie, Université de Montréal, Montréal, Québec, Canada
New NIOSH guidelines on reproductive risks associated with hazardous drug exposures in healthcare workers: Recommendations for reducing exposures T. H. Connor¹, C. C. Lawson² 1 PhD, Division of Applied Research and Technology
2 PhD, Division of Surveillance, Hazard Evaluations and Field Studies
National Institute for Occupational Safety and Health, Cincinnati, OH USA
Water micropollutants in Bordeaux area: Strategy for reducing the contamination in an urban territory D. Granger Project manager, SUEZ

Hot topics in pharmaceutical technology

What glove to choose for work in an isolator? J.C. Lucas Directeur Général Piercan, France A simulator for the training and assessment of professional competences of personnel working in an aseptic environment M. Denami Expert pédagogique, Université de Strasbourg et société Whitequest, France Implementing european recommandations for the preparation of short shelf-lived radiopharmaceuticals for diagnostic purposes in molecular imaging G. Meffre Nuclear Medicine Department, CHU de Liège, Belgium Design and validation of a risk matrix for the assessment of sterile compounded preparations AM. Martin de Rosales, C. López Cabezas Spanish Group of Hospital
Pharmacy Compounding from the Spanish Society of Hospital Pharmacy

Short oral communications

Medical and Pharmaceutical cooperation as a contributor to the success of pediatric allogeneic hematopoietic stem-cell transplantation (allo-HSCT): inclusion process ability via the therapeutic drug monitoring (TDM) of busulfan (Bu) A. Lalli¹, A. Amin¹, F. Vidal¹, S. Poil¹, E. Fonsat¹, B. Neven², M-L. Fremond², E. Elkaim², M. Castelle², S. Blanche², Ph. Bourget¹ 1 Service de Pharmacie Clinique,
2 Service Unité d’Immuno-Hématologie et Rhumatologie Pédiatrique,
HU Necker-Enfants Malades - 149 rue de Sèvres, 75015 Paris, France Determination of the microbiological stability of intrathecal chemotherapy G. Binson¹, L. Danguy des Déserts¹, A. Bousseau², A.-C. De Boisgrollier¹, I. Princet¹ 1 Pharmacie – Unité de Reconstitution des Cytotoxiques - CHU de la Milétrie - Poitiers, France
2 Unité d’Hygiène hospitalière - CHU de la Milétrie - Poitiers, France
Preventing workers contamination during solid oral doses repackaging : Why and How? A. Sgarioto¹, H. Ginestet¹, S. Armand-Branger² 1 Pharmacie à Usage Intérieur - HIA du Val de Grâce, Paris
2 Pharmacie à Usage Intérieur - CESAME, Sainte Gemmes sur Loire
Preparation of frozen stool suspensions for fecal microbiota transplantation M. Jobard, C. Madaoui, O. Fabre, M.L. Brandely, R. Batista, F. Chast Service de Pharmacie, GH Hôpitaux Universitaires Paris Centre,
site Hôtel-Dieu, 1 place du Parvis Notre Dame, 75004 Paris, France
Contribution of the pharmaceutical expertise to the extemporaneous shaping of special catheters for intracerebral injections (ICI) during neurosurgical procedures: application to three clinical trials of gene therapy (GT) in the setting of serious metabolic diseases R. Loeuillet¹, A. Amin¹, C. Violain¹, S. Teixeira¹, V. Afonso¹, N. Thromas¹, M. Tardieu³, M. Zerah², P. Aubourg², C. Sevin², T. Baugnon³, R. Crystal⁴, K. Belahreche1, V. Zaugg¹, C. Broissand¹, P. Bourget¹ 1 Service de Pharmacie Clinique, HU Necker-Enfants Malades, Paris, France
2 Service de Neurologie Pédiatrique - Centre de Référence des Leucodystrophies, Hôpital Bicêtre, Paris, France
3 Service Anesthésie-Réanimation-SAMU-SMUR, HU Necker-Enfants Malades, Paris, France
4 Weill Cornell University, Department of Genetic Medicine, New-York, NY, USA
Integrity testing for sterile preparation syringes A. Pilon¹, A.C Gairard Dory¹, L. Belotti², J. Bourbon¹, B. Gourieux¹ 1 Service de pharmacie-stérilisation
2 Laboratoire d’hygiène
Hôpitaux Universitaires de Strasbourg - France
Evaluation of physical constraints related to the use of medical devices during the cytotoxic compounding C. Roch¹, N. Martelli¹, J. Vernois², D. Pradeau³, E. Caudron^1,4 1 Service Pharmacie, Hôpital européen Georges Pompidou, AP-HP, France
2 Unité Qualité et Essais Hospitaliers, AGEPS, AP-HP, France
3 Laboratoire de Physico-chimie, AGEPS, AP-HP, France
4 Laboratoire de chimie analytique Lyp(Sys)2, Université Paris Sud, France Differences in disinfection protocols of raw material vials intended to the production of parenteral nutrition mixtures C. Humbert, C. Cros, F. Nadji, J. Bordenave, G. Benoit Hôpital Armand Trousseau, 26, avenue du Docteur Arnold-Netter, 75012 Paris, France
Operational qualification of an automated compounding device of parenteral nutrition : Medimix® IMF M. Garcès, R. Vazquez, MN. Guerrault-Moro, A. Durand Pharmacie - Pharmacotechnie, Centre Hospitalier Intercommunal de Poissy Saint-Germain-en-Laye,
Saint-Germain-en-Laye, France
Validation of the BacT/Alert® method for microbiological control of pediatric parenteral nutrition (PPN) mixtures C. Le Roy¹, E. Bermudez¹, N. Carre¹, C. Chanat¹, C. Castelain¹, H. Poutet², M.L. Brunet¹, F. Chastv 1 Pharmacy department
2 Bacteriology department
Hôpitaux Universitaires Paris Centre Cochin Broca Hôtel-Dieu,
27 rue du Faubourg-Saint-Jacques, 75014 Paris, France Contamination of calcium gluconate solutions by aluminum: which consequences for parenteral nutrition in neonatology? B. Raspaud, A. Venet, A. Jourand, S. Mesli, J. Grellet, D. Breilh, S. Crauste-Manciet CHU de Bordeaux, Matrice Pharmacotechnie,
Pôle des produits de Santé, Bordeaux, France A single fluorescein-combined media fill test for validation of good practices concerning both radiopharmaceutical preparations asepsis and radioprotection A-S. Chantry, C.F. d’Andon, A. Gouillet, Ph. Garrigue, B. Guillet Radiopharmacie AP-HM,
Hôpital Nord, Marseille Stability assessment of Teicoplanin infusions in 0.9% sodium chloride in various infusion devices J. Holden Quality Control North West, Stepping Hill Hospital, Stockport, UK
Viability of selected microorganisms in non-cytotoxic aseptic preparations I. Sarakbi, I. Krämer Department of Pharmacy, University Medical Center Mainz,
Johannes Gutenberg-University,
Langenbeckstraße 1, 55131 Mainz, Germany
How and why did we set up a Controlled Atmosphere Area of errors ? V. Klaczynski, A. Beausir, C. Fournier Centre Hospitalier de Lens, France Impact of operators and pharmaceutical operations on air quality of controlled atmosphere areas S. Filali, B. Darricau, C. Bretagnolle, E. Diouf, D. Salmon, M.L. Tall, C. Pivot, F. Pirot Pharmacie, Hôpital Édouard Herriot,
Lyon, France Stability study of a 10 mg/ml concentrated solution of doxorubicin M. Boutet¹, T. Briot^1,2, S. Vrignaud¹, F. Lagarce^1,2 1 CHU Angers, service pharmacie, Angers, France
2 L’université Nantes Angers Le Mans, INSERM U1066, Micro et nanomédecines biomimétiques,
Angers, France Cytotoxic contamination level follow-up during the implementation of an automated compounding system N. Creus¹, C. Lopez Cabezas¹, M. Oliveras², G. Cajaraville³, N. Telleria⁴ 1 Hospital Clinic, Barcelona
2 Hospital Vall d’Hebron, Barcelona
3 Onkologikoa, San Sebastian
4 KIRO Robotics S.L. Spain
Study of environmental contamination in the pharmacy and oncology departments of the Institut Curie T. Rusu, J. Fouque, F. Cartier, S. Thevenet, L. Escalup Pharmacie Institut Curie,
Paris, France
Isolator: Does a break of containment leads always to a break of sterility ? E. Sigward, X. Breton, C. Mannechin, P. Faure, N. Jourdan Unité de préparation des anticancéreux
Service Pharmacie CHU Saint-Louis, Paris Stability of 25 mg/mL 5-azacitidine suspensions kept in fridge after freezing C. Balouzet, C. Chanat, M. Jobard, M-L. Brandely-Piat, F. Chast Service de Pharmacie, GH Hôpitaux Universitaires Paris Centre
Site Hôtel Dieu, 1 place du Parvis Notre-Dame
75004 Paris, France Evaluation of a new quality-control system for cytotoxics based on UV-visible spectrophotometry (DrugLog®) F. Feutry^1,2, A. Exquis^2,3, L. Falaschi², N. Guichard^2,3, P. Odou¹, P. Bonnabry^2,3, S. Fleury² 1 UDSL, EA GRITA, Univ Lille, 3 rue du Professeur Laguesse, F-59000, Lille, France
2 Pharmacy, Geneva University Hospitals, 4 Rue Gabrielle-Perret-Gentil CH-1211 Geneva 14, Switzerland
3 Section of pharmaceutical sciences, University of Geneva, University of Lausanne, Geneva, Switzerland New approach for rapid, non-invasive and non-destructive quantification by near infrared spectroscopy (NIRS): Application to amoxicillin infusion L. Lê^1,2, L. Eveleigh³, P. Prognon^1,2, E. Caudron^1,2 1 Université Paris Sud, Groupe de Chimie Analytique Paris Sud, Lip(Sys)², Chatenay Malabry, France
2 Hôpital Européen Georges Pompidou (AP-HP), Service de Pharmacie, Paris, France
3 AgroParisTech, INRA, Laboratoire de Chimie Analytique, Paris, France Identification of 1ml and 3ml syringes by video camera to control drug compounding M. Henriquet, E. Fougereau, F. Benizri Institut Paoli Calmettes,
Marseille, France
Pilot project of RFID tags suitable for tracking cancer chemotherapy preparations M. Lafay-Bourquin, C. Giard, J. Rambaud, I. Ferry, L. Escalup Institut Curie - Hôpital René Huguenin, service Pharmacie, 35 rue Dailly
92210 Saint-Cloud, France

Workshops

Workshop 1 : Isolator validation for hospital pharmacy preparation Modérateurs : F. Sadeghipour¹, P. Hild², D. Meyer³ 1 Pharmacien, Chef de service CHUV, Lausanne
2 PH Pharmacien, Chef de Service Roanne
3 Expert micro-environnements - DMcompliance Workshop 3: Education tool for hospital technicians used in an injectable cytotoxic preparation service Modérateurs : C. Nowak¹, L. Danguy des Déserts², D. Lucas¹, P. Rohrbach³ 1 CH Angoulême
2 CH de Poitiers
3 CH de Verdun Workshop 4: New UK standards for aseptic preparation of paediatric parenteral nutrition and comparison with European standards Modérateurs : A. Beaney¹, R. Bateman² 1 North-East England, UK
2 East and South East England, UK Workshop 5: ADKA-Guidelines: Interactive discussion of the revised version of the ADKA-Guideline ‘Drug manufacturing and quality control’ and the draft guideline ‘Oncolytic viruses’ (German language) Irene Krämer Department of Pharmacy, University Medical Center,
Johannes Gutenberg-University, Langenbeckstraße 1,
55131 Mainz, Germany

posters

Photos

In plenary session Workshops The relaxation area