2011 Conference
14th GERPAC Conference
9th European GERPAC
Sterile drugs preparation in hospital pharmacies
9th European GERPAC
Sterile drugs preparation in hospital pharmacies
October 5, 6 & 7 - Hyères - France
Procedure evaluation for aseptic compouding
Evaluation of disinfecting procedures for aseptic transfer in hospital pharmacy
J.C. Smith
All Wales Quality Assurance Pharmacist,
St Mary’s Pharmaceutical Unit Cardiff & Vale
Cardiff & Vale University Health Board, Cardiff, UK Biological indicators for sterilisation in an isolator M. Meyer Internal validation manager,
Getinge Life Sciences,
Vendôme, France Aseptic filling tests in hospital pharmacy: advantages and limits O. Chancel Head of pharmaceutical support,
MERIAL, Lyon, France
St Mary’s Pharmaceutical Unit Cardiff & Vale
Cardiff & Vale University Health Board, Cardiff, UK Biological indicators for sterilisation in an isolator M. Meyer Internal validation manager,
Getinge Life Sciences,
Vendôme, France Aseptic filling tests in hospital pharmacy: advantages and limits O. Chancel Head of pharmaceutical support,
MERIAL, Lyon, France
Contamination risks highlights
Cytotoxic Drugs in Drinking Water
J. Fawell, E.H. Goslan
WHO Guidelines Committee and Cranfield University
Managing cross-contamination for highly potent sterile drugs
M. Laugier
Development and project director,
CREAPHARM, Riom, France Microbiological Risks Quantified During IV Drug Delivery System Preparation E. Tidswell Senior Director, Research Sterility
AssuranceTechnology Resources
Baxter Healthcare Corporation, USA
CREAPHARM, Riom, France Microbiological Risks Quantified During IV Drug Delivery System Preparation E. Tidswell Senior Director, Research Sterility
AssuranceTechnology Resources
Baxter Healthcare Corporation, USA
Filling process in aseptic compounding
Aseptic filling: Methods
F. Sadeghipour
Pharmacie des Hôpitaux Universitaires de Genève (HUG),
Genève, Suisse Pumps for the aseptic preparation of cytotoxic chemotherapy syringes I. Roland1, Michel Deprez1, Bénédikte Hébert2, Yvan Huon1 1 Pharmacie CHU Liège, Liège, Belgique
2 Pharmacie Centre Hospitalier Laennec, Creil, France Robot for aseptic compounding of cytotoxics A. Hurgon, A. Chassin, C Giard, L. Escalup Institut Curie, service Pharmacie,
Paris Microbiological cleanliness assessment of cytotoxic compounding robot A. Ogunsanlu Pharmacy Executive Lead: Quality Assurance/Quality Control ,
Imperial College Healthcare NHS Trust, UK The technician’s point of view on the use of robots for the preparation of cytotoxics F. Pichon, R. Oubaïda, L. Derai, V. Chancelade, S. Dieng, A. Ahalli, E. Barbagelata and the entire team of technicians
Curie Institute, service Pharmacie,
26 rue d’Ulm 75248 Paris cedex 05
Genève, Suisse Pumps for the aseptic preparation of cytotoxic chemotherapy syringes I. Roland1, Michel Deprez1, Bénédikte Hébert2, Yvan Huon1 1 Pharmacie CHU Liège, Liège, Belgique
2 Pharmacie Centre Hospitalier Laennec, Creil, France Robot for aseptic compounding of cytotoxics A. Hurgon, A. Chassin, C Giard, L. Escalup Institut Curie, service Pharmacie,
Paris Microbiological cleanliness assessment of cytotoxic compounding robot A. Ogunsanlu Pharmacy Executive Lead: Quality Assurance/Quality Control ,
Imperial College Healthcare NHS Trust, UK The technician’s point of view on the use of robots for the preparation of cytotoxics F. Pichon, R. Oubaïda, L. Derai, V. Chancelade, S. Dieng, A. Ahalli, E. Barbagelata and the entire team of technicians
Curie Institute, service Pharmacie,
26 rue d’Ulm 75248 Paris cedex 05
Hyperthermic In traperitoneal Chemo therapy (HIPEC)
How to protect those involved in performing open abdomen hyperthermic intraoperative intraperitoneal chemotherapy against exposure to antimitotics?
P. Rat, O. Facy, M. Poussier, N. Cheynel, G. Di Giacomo, P. Ortega Deballon
Service de Chirurgie digestive et cancérologique,
CHU Dijon, France Surface Contamination by Cis/Oxaliplatin during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) R. Schierl Institute for Occupational, Social and Environmental Medicine,
Munich University, Munich, Germany
(Director Prof. D. Nowak, M.D.) Biological monitoring of personnel during HIPEC procedure: Evaluation of platinum in blood and urine H. Anundi1, S. Näslund-Andéason 2, H.Matheme 3. 1 Department of Occupational and Environmental Medicine,
2 Department of Main Operating Theatres,
3 Department of Surgery,
Uppsala University Hospital, Sweden
CHU Dijon, France Surface Contamination by Cis/Oxaliplatin during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) R. Schierl Institute for Occupational, Social and Environmental Medicine,
Munich University, Munich, Germany
(Director Prof. D. Nowak, M.D.) Biological monitoring of personnel during HIPEC procedure: Evaluation of platinum in blood and urine H. Anundi1, S. Näslund-Andéason 2, H.Matheme 3. 1 Department of Occupational and Environmental Medicine,
2 Department of Main Operating Theatres,
3 Department of Surgery,
Uppsala University Hospital, Sweden
Short oral scientific communications
Advantages of using a peristaltic pump for dose banding of cytotoxic drugs
A.G. Caffin, R. Vazquez, M.N. Guerrault-Moro, D. Brossard, S. Crauste-Manciet
Centre Hospitalier Poissy-Saint Germain en Laye,
Service Pharmacie, Saint Germain en Laye, France Evaluation of the advantages to be derived from automating injectable hospital preparations of paediatric synges and analgesia bags F. Gass-Jegu, M. Rigo Adrover, A.C. Gairard-Dory Service de Pharmacie-Stérilisation,
Nouvel Hôpital Civil,
1 Place de la Porte de l’Hôpital, 67000 Strasbourg
Validation of the stage for homogenisation of chemotherapy bags by introducing analytical spot checking A. Fuss, V. Graff Pharmacie, Clinique Ste Anne,
Strasbourg, France Analysis of different cytotoxic chemotherapy control methods in 30 french hospitals J. Descout, C. Grignon, S. Coulon, A. Dauphin Service de pharmacie, unité centralisée de préparation des cytotoxiques,
groupe hospitalier Cochin-Saint Vincent de Paul,
27 rue Faubourg Saint-Jacques, 75679 Paris, France Application of Raman Spectroscopy to the analysis of complex Therapeutic Objects: Analytical Quality Control and Release Testing of portable infusion devices with a polyisoprene membrane charged with 5FU A. Amin, Ph. Bourget, F. Vidal, L. Falaschi, R. Clément Service de Pharmacie Clinique, GH Necker - Enfants Malades,
AP-HP, 149 rue de Sèvres,
F-75015, Paris, France
Sterility test for ophtalmic preparations on R2A solid state medium M. Saliège1, E. Thibert1, F. Chapelle2, V. Sautou1, O. Traoré2, J. Chopineau1 1 Service Pharmacie, CHU Clermont-Ferrand
2 Laboratoire Hygiène Hospitalière, CHU Clermont-Ferrand Evaluation of the lead-time for availability of chemotherapies in four hospital centres N. Cormier1, M. Adam2, S. Roche3, S. Hannou4 1 Service Pharmacie Hôpital Européen Georges Pompidou,
2 Service Pharmacie Centre Hospitalo-universitaire de Rouen,
3 Service Pharmacie Centre Hospitalier d’Aix-en-Provence,
4 Service Pharmacie Hôpitaux Universitaires de Strasbourg.
Environmental inspections of radiopharmacy premises and equipment: prevailing conditions in France A.C. de Boisgrollier1 ; S. Edet2 ; M. Zarid-Chakik3 1 : Unité de radiopharmacie, Centre Henri Becquerel, Rouen
2 : Unité de radiopharmacie, Hôpital St Louis, Paris
3 : Unité de radiopharmacie, Hôpital Européen Georges Pompidou, Paris Surveillance of microbiological contamination in a CAZ devoted to the reconstitution of cytotoxics N. Bouzina, M. Desbourdes, M. Montana, F. Peyron, M. Bues-Charbit Oncopharma Nord- hôpital nord, chemin des bourrely,
13015 marseille, tel 04 91 96 89 89
Evaluation of chemical contamination when preparing chemotherapy treatments within a CCRU S. Taurin, G. Kerjean, A. Brouard, A. Levron Service Pharmacie, Centre Hospitalier Bretagne Sud Provision of a tool to train in the use of Multispec A.Camut, V.Noirez, A.Khalifé Pharmacie Hôpital Bon Secours, Metz Survey of cytotoxic contamination within a reconstitution unit S. Nussbaumer1,2,3, M. Mattiuzzo1, L. Geiser3, F. Sadeghipour1, S. Fleury-Souverain1, P. Bonnabry1,2 1 Pharmacie des Hôpitaux Universitaire de Genève (HUG),
2 Section des sciences pharmaceutiques, Université de Genève, Université de Lausanne,
3 Swiss Centre for Applied Human Toxicology, Genève, Suisse Cytostatic surface contamination in an automated robotic system (CytoCareTM) in comparison to the manual compounding process B. Gandré, I. Krämer Apotheke der Universitätsmedizin der Johannes Gutenberg-Universität Mainz,
Langenbeckstrasse 1, 55131 Mainz, Germany Simulating the risks of cross-contaminations relating to handling errors K. Boubet, A.Jebahi, R. Vazquez, M.N. Guerrault-Moro, D. Brossard, S. Crauste-Manciet Centre Hospitalier Poissy-Saint Germain en Laye, Service Pharmacie, Saint Germain en Laye, France Monitoring surface chemical contaminations in the chemotherapy control laboratory L. Lê1, E. Caudron1, H. Sadou Yaye2, D. Pradeau2, P. Prognon1, L. Havard1 1 Pharmacie, Hôpital Européen Georges Pompidou (AP-HP), France
2 Laboratoire de Développement Analytique, Agence Générale des Equipements et Produits de Santé (AP-HP), France Evaluation of the effectiveness of surface decontamination agents on ten antineoplasic agents T. Queruau Lamerie1,2, S. Nussbaumer3, P. Odou1,2, J.F. Goossens2, S. Souverain-Fleury3, P. Bonnabry3 1 Institut de Pharmacie, CHRU, Lille, France
2 GRIIOT, EA 4481 Université Lille Nord de France UDSL, Lille, France
3 Pharmacie des Hôpitaux Universitaires de Genève et Section des sciences pharmaceutiques, Genève, Suisse Making the circuit for cytotoxics safe, an unconvincing track record for the pharmaceutical laboratories M. Faucon, C. Combis, V. Vialle, V. Dehondt, E. Janvier, F. Monard Pharmacie Centre Hospitalier de Calais, 11 quai du commerce
62100 Calais, France Experience in surgical practice using Savene (dexrazoxane) to treat anthracycline extravasations F. Duvivier CHPLT, Verviers, Belgique Working out a decision-making scorecard to match staffing levels to the nature of cytotoxics to be prepared A. Secq, C. Van-Tuyckom, F. Danicourt, J.P. Résibois Service Pharmacie. Centre hospitalier de Dunkerque,
130 avenue Louis Herbeaux
59385 Dunkerque, France Acquisition of a management software package, working up and control of extemporaneous and hospital preparations: specifications and analysis of proposals J. Marcel1, L. Trigory2, F. Gass-Jegu3, M. Bourges4, C. Le Tiec1, S. Ménétré2, A. Coquard4, A.C. Gairard-Dory3 1 Service de pharmacie, CHU de Bicêtre, 78 rue du Général Leclerc, 94275 Kremlin-Bicêtre
2 Pôle Pharmacie-Stérilisation, CHU Nancy Brabois Enfants, Allée du Morvan, 54511 Vandoeuvre les Nancy,
3 Service de Pharmacie-Stérilisation, Nouvel Hôpital Civil, 1 Place de la Porte de l’Hôpital, 67000 Strasbourg
4 Service de Pharmacie, CHU Charles NICOLLE, 1 rue de Germont, 76000 Rouen Cytarabin and different concentrations: how to take big risks in paediatrics! M. Coussemacq, G. Baussant, J. Aubert, A. Wibaux, V. Moinard, C. Delette Service Pharmacie, Centre Hospitalier de Roubaix, France
Service Pharmacie, Saint Germain en Laye, France Evaluation of the advantages to be derived from automating injectable hospital preparations of paediatric synges and analgesia bags F. Gass-Jegu, M. Rigo Adrover, A.C. Gairard-Dory Service de Pharmacie-Stérilisation,
Nouvel Hôpital Civil,
1 Place de la Porte de l’Hôpital, 67000 Strasbourg
Validation of the stage for homogenisation of chemotherapy bags by introducing analytical spot checking A. Fuss, V. Graff Pharmacie, Clinique Ste Anne,
Strasbourg, France Analysis of different cytotoxic chemotherapy control methods in 30 french hospitals J. Descout, C. Grignon, S. Coulon, A. Dauphin Service de pharmacie, unité centralisée de préparation des cytotoxiques,
groupe hospitalier Cochin-Saint Vincent de Paul,
27 rue Faubourg Saint-Jacques, 75679 Paris, France Application of Raman Spectroscopy to the analysis of complex Therapeutic Objects: Analytical Quality Control and Release Testing of portable infusion devices with a polyisoprene membrane charged with 5FU A. Amin, Ph. Bourget, F. Vidal, L. Falaschi, R. Clément Service de Pharmacie Clinique, GH Necker - Enfants Malades,
AP-HP, 149 rue de Sèvres,
F-75015, Paris, France
Sterility test for ophtalmic preparations on R2A solid state medium M. Saliège1, E. Thibert1, F. Chapelle2, V. Sautou1, O. Traoré2, J. Chopineau1 1 Service Pharmacie, CHU Clermont-Ferrand
2 Laboratoire Hygiène Hospitalière, CHU Clermont-Ferrand Evaluation of the lead-time for availability of chemotherapies in four hospital centres N. Cormier1, M. Adam2, S. Roche3, S. Hannou4 1 Service Pharmacie Hôpital Européen Georges Pompidou,
2 Service Pharmacie Centre Hospitalo-universitaire de Rouen,
3 Service Pharmacie Centre Hospitalier d’Aix-en-Provence,
4 Service Pharmacie Hôpitaux Universitaires de Strasbourg.
Environmental inspections of radiopharmacy premises and equipment: prevailing conditions in France A.C. de Boisgrollier1 ; S. Edet2 ; M. Zarid-Chakik3 1 : Unité de radiopharmacie, Centre Henri Becquerel, Rouen
2 : Unité de radiopharmacie, Hôpital St Louis, Paris
3 : Unité de radiopharmacie, Hôpital Européen Georges Pompidou, Paris Surveillance of microbiological contamination in a CAZ devoted to the reconstitution of cytotoxics N. Bouzina, M. Desbourdes, M. Montana, F. Peyron, M. Bues-Charbit Oncopharma Nord- hôpital nord, chemin des bourrely,
13015 marseille, tel 04 91 96 89 89
Evaluation of chemical contamination when preparing chemotherapy treatments within a CCRU S. Taurin, G. Kerjean, A. Brouard, A. Levron Service Pharmacie, Centre Hospitalier Bretagne Sud Provision of a tool to train in the use of Multispec A.Camut, V.Noirez, A.Khalifé Pharmacie Hôpital Bon Secours, Metz Survey of cytotoxic contamination within a reconstitution unit S. Nussbaumer1,2,3, M. Mattiuzzo1, L. Geiser3, F. Sadeghipour1, S. Fleury-Souverain1, P. Bonnabry1,2 1 Pharmacie des Hôpitaux Universitaire de Genève (HUG),
2 Section des sciences pharmaceutiques, Université de Genève, Université de Lausanne,
3 Swiss Centre for Applied Human Toxicology, Genève, Suisse Cytostatic surface contamination in an automated robotic system (CytoCareTM) in comparison to the manual compounding process B. Gandré, I. Krämer Apotheke der Universitätsmedizin der Johannes Gutenberg-Universität Mainz,
Langenbeckstrasse 1, 55131 Mainz, Germany Simulating the risks of cross-contaminations relating to handling errors K. Boubet, A.Jebahi, R. Vazquez, M.N. Guerrault-Moro, D. Brossard, S. Crauste-Manciet Centre Hospitalier Poissy-Saint Germain en Laye, Service Pharmacie, Saint Germain en Laye, France Monitoring surface chemical contaminations in the chemotherapy control laboratory L. Lê1, E. Caudron1, H. Sadou Yaye2, D. Pradeau2, P. Prognon1, L. Havard1 1 Pharmacie, Hôpital Européen Georges Pompidou (AP-HP), France
2 Laboratoire de Développement Analytique, Agence Générale des Equipements et Produits de Santé (AP-HP), France Evaluation of the effectiveness of surface decontamination agents on ten antineoplasic agents T. Queruau Lamerie1,2, S. Nussbaumer3, P. Odou1,2, J.F. Goossens2, S. Souverain-Fleury3, P. Bonnabry3 1 Institut de Pharmacie, CHRU, Lille, France
2 GRIIOT, EA 4481 Université Lille Nord de France UDSL, Lille, France
3 Pharmacie des Hôpitaux Universitaires de Genève et Section des sciences pharmaceutiques, Genève, Suisse Making the circuit for cytotoxics safe, an unconvincing track record for the pharmaceutical laboratories M. Faucon, C. Combis, V. Vialle, V. Dehondt, E. Janvier, F. Monard Pharmacie Centre Hospitalier de Calais, 11 quai du commerce
62100 Calais, France Experience in surgical practice using Savene (dexrazoxane) to treat anthracycline extravasations F. Duvivier CHPLT, Verviers, Belgique Working out a decision-making scorecard to match staffing levels to the nature of cytotoxics to be prepared A. Secq, C. Van-Tuyckom, F. Danicourt, J.P. Résibois Service Pharmacie. Centre hospitalier de Dunkerque,
130 avenue Louis Herbeaux
59385 Dunkerque, France Acquisition of a management software package, working up and control of extemporaneous and hospital preparations: specifications and analysis of proposals J. Marcel1, L. Trigory2, F. Gass-Jegu3, M. Bourges4, C. Le Tiec1, S. Ménétré2, A. Coquard4, A.C. Gairard-Dory3 1 Service de pharmacie, CHU de Bicêtre, 78 rue du Général Leclerc, 94275 Kremlin-Bicêtre
2 Pôle Pharmacie-Stérilisation, CHU Nancy Brabois Enfants, Allée du Morvan, 54511 Vandoeuvre les Nancy,
3 Service de Pharmacie-Stérilisation, Nouvel Hôpital Civil, 1 Place de la Porte de l’Hôpital, 67000 Strasbourg
4 Service de Pharmacie, CHU Charles NICOLLE, 1 rue de Germont, 76000 Rouen Cytarabin and different concentrations: how to take big risks in paediatrics! M. Coussemacq, G. Baussant, J. Aubert, A. Wibaux, V. Moinard, C. Delette Service Pharmacie, Centre Hospitalier de Roubaix, France
Workshops
Workshop 1 : Sterile Preparations for clinical trials
Moderators: P. Bonnabry, F. Lagarce, V. Daniel
Workshop 2 : ISO 9001 Certification
Moderators: V. Chedru, D. Dautel, D. Noël
Workshop 3 : Facilities and environment design for sterile preparation
Moderators : G. Podilsky, D. Lammerant