2021 Conference
24th European GERPAC Conference
October 6, 7 & 8, 2021 - Hyères - France
In this space, you will find all the congress communications including conferences, round table, videos, short oral communications and poster presentations.
Concurrent workshops
Content-container Interactions
P. Chennell, V. Sautou (Clermont-Ferrand - France)
New Best Practices for Preparation (French regulations)
S. Crauste-Manciet (Bordeaux - France) Ph. Poulet (Lyon - France)
V. Salomon (Saint Denis - France)
T. Storme (Paris - France)
Development of an accreditation program in nonsterile compounded drugs
A-F. Dumas (Valence - France)R. Mazet (Grenoble - France)
How to optimise the robustness and safety of a hospital compounding by monitoring relevant indicators?
M-L. Brandely-Piat (Paris - France)L. Escalup (Paris - France)
P. Odou (Lille - France)
Hot topics in aseptic preparation
I. Kramer (Mainz - Germany)P. Le Brun (Leiden - The Netherland)
F. Sadeghipour (Lausanne - Switzerland)
Quebec ASSTSAS Guide
Moderators
ML. Brandely-Piat, (Paris - France)D. Brossard (Paris - France)
Prevention guide on handling hazardous drugs: highlights from the 2nd edition of the guide
JF. Bussières (Montréal, Québec - Canada)
Round table: future for the pharmaceutical technologies in hospital pharmacy
Future for the pharmaceutical technologies in hospital pharmacy
P. Odou (Lille, France)T. Schnor (Herlev, Denmark)
T. Briot (Lyon, France)
I. Kramer (Mainz, Germany)
P. Le Brun (Leiden, The Netherland)
S. Crauste-Manciet (Bordeaux, France)
Shortage of curares in France during the COVID-19 crisis. What were the findings?
P. Odou (Lille, France)
Use of isolators as part of the future technology in the hospital pharmacies in Denmark ?
T. Schnor (Herlev, Denmark)
Preparations and formulations for phage therapy
T. Briot (Lyon, France)
Robotics for the preparation of ready-to-administer parenterals in hospital pharmacies
I. Krämer (Mainz, Germany)
3D printing of personalised medicines
P. Le Brun (Leiden, The Netherland)
Preparation of Advanced Therapy Medicinal Products
A. Black (Newcastle, UK)
RNA-based vaccines
RNA-based vaccines
F. Lagarce (Angers - France)D. Parsons (Cambridge (MA) - USA)
V. Sautou (Clermont Ferrand - France)
D. Brossard (Paris - France)
Industrial manufacturing
D. Parsons (Cambridge (MA) - USA)
Formulation and stability of mRNA vaccines: the pharmacist’s point of view
F. Lagarce, C. Bris, V. Lebreton (Angers - France)
Hot topics 2021 Hospital Pharmaceutical Technologies
INNOVATIONS IN PHARMACEUTICALS TECHNOLOGIES
Automated Oral Liquid Compounding Technology with Internal Engineering Controls for Hazardous Compounding
J. D’Silva (Ohio - USA)
Solution against MSD
P. Freydier - Romeo by O3P
Dispofill system® (DFS) - Single use isolator
E. Goyer - JCE Biotechnology
Pre-filled syringes made of cyclic olefin copolymers for the hospital environment
N. Niederwieser – Schott
HOT TOPICS FROM FRENCH SUPERVISORY AUTHORITIES
Development by Ile-de-France Regional Health Agency (IDF-RHA) of a self-assessment tool, ChimioPREP, to secure production of sterile chemotherapy (cytotoxic and other anticancer drugs)
F. Lepagnol, M. Talla, M. Kolski, V. Godinot
Quality, Security, Pharmacy, Drug and Biology Department, Ile de France Regional Health Agency (IDF-RHA)
Updating from French National Agency for Medicines and Health products safety
V. Salomon - Directrice - Direction des métiers scientifiques - Agence Nationale de la Sécurité des Médicaments
Automated Oral Liquid Compounding Technology with Internal Engineering Controls for Hazardous Compounding
J. D’Silva (Ohio - USA)
Solution against MSD
P. Freydier - Romeo by O3P
Dispofill system® (DFS) - Single use isolator
E. Goyer - JCE Biotechnology
Pre-filled syringes made of cyclic olefin copolymers for the hospital environment
N. Niederwieser – Schott
HOT TOPICS FROM FRENCH SUPERVISORY AUTHORITIES
Development by Ile-de-France Regional Health Agency (IDF-RHA) of a self-assessment tool, ChimioPREP, to secure production of sterile chemotherapy (cytotoxic and other anticancer drugs)
F. Lepagnol, M. Talla, M. Kolski, V. GodinotQuality, Security, Pharmacy, Drug and Biology Department, Ile de France Regional Health Agency (IDF-RHA)
Updating from French National Agency for Medicines and Health products safety
V. Salomon - Directrice - Direction des métiers scientifiques - Agence Nationale de la Sécurité des Médicaments
Pharmaceutical Technology Master course’s award
Moderators
Dr ML. Brandely-Piat (Paris - France)Pr D. Brossard (Paris - France)
Semi-solid extrusion 3D printing of orodispersible caffeine films based on sodium alginate for neonates
Agnès Roche1, Noelia M Sanchez-Ballester1,2, Adrien Aubert 1, Sylvie Begu 1, Ian Soulairol 1,2 1 ICGM, Univ Montpellier, CNRS, ENSCM, Montpellier, France
2 Department of Pharmacy, Nîmes University Hospital, France
Hospital production of propofol injectable nanoemulsion: proof-of-concept
A. Cèbe1, B. Dessane1,2, A. Venet1, JM Bernadou1, F Xuereb1, 3 , S . Crauste-Manciet1, 21 Pharmaceutical Technology Department, Bordeaux University Hospital, France
2 ARNA Laboratory ChemBioPharm U1212 INSERM - UMR 5320 CNRS, Bordeaux University, France
3 Pharmacokinetics and PK/PD Group, INSERM 1034, University of Bordeaux, France
Development and preformulation of an injectable solution of propofol complexed with cyclodextrin
M. BouchfaaCHU Lille, Institut de pharmacie, F-59000 Lille, France
Univ. Lille, EA 7365 – GRITA – Groupe de Recherches sur les formes Injectables et les Technologies Associées, F-59000 Lille, France
GERPAC award for the best oral communication
GERPAC 2021 video competition
Short oral communications
Moderators
Y. Huon (Liège - Belgium)F. Lagarce (Angers - France)
F. Sadeghipour (Lausanne - Switzerland)
Lean Six-sigma method: application in Chemotherapy Reconstitution Unit (URC)
Perrine Hardy1, Sara Molignier1, Isabelle Princet11 Chemotherapy Reconstitution Unit, CHU Poitiers, 2 rue de la milétrie, France
Kinetics of degradation amoxicillin and clavulanic acid
M. Petit, V. Lebreton , F. Saïag, F. LagarcePharmacy, CHU Angers, France
Identification and risk analysis of a robotized chemotherapy manufacturing process
Bouchfaa Myriam1, 2, Courtin Justin1, Pinturaud Marine1, Vasseur Michèle1, 2, Odou Pascal1, 21- CHU Lille, Institut de pharmacie, F-59000 Lille, France
2- Univ. Lille, EA 7365 – GRITA – Groupe de Recherches sur les formes Injectables et les Technologies Associées, F-59000 Lille, France
Cord Blood Serum Eye Drops: application of the collection circuit and of the qualification of donations
Alessandra Hinic1, Amélie Benin3, Coryne Hildebert3, Marion Jobard2, Marie-Laure Brandely-Piat1, Rui Batista1, 21-Unité de Préparations Stériles Ophtalmologiques et Oncologiques, 2- Unité d’Assurance Qualité, Service de Pharmacie Clinique, 3- Service d’Obstétrique, GH Centre Université de Paris, AP-HP, Hôpital Cochin, 27 rue du faubourg St Jacques, 75014 Paris, France
Optimisation of the use of Picomix® for amiodarone and lactose powders mixing
Alloh Nammou D., Lefebvre E., Kansou E., Royer M., Mustapha L., Marçon F.CHU Amiens-Picardie, Amiens, France
Formulation of a new paediatric phenobarbital oral solution
L. Parrenne1, 3, Z. Ribier3, J. Abisror2, 3, S. Ahil3, C. Figueiredo3, P. Marchadour3, G. Benoit3, J. Bordenave31 Faculty of Pharmacy of Paris, Paris, France
2 Faculty of Pharmacy Paris-Saclay, Châtenay-Malabry, France
3 Pharmacy, Armand Trousseau Hospital, APHP, Paris, France
Intravenous hospital preparations for treatment of Covid19: an inter-laboratory comparison of cisatracurium quantification
Philip Chennell1, Chloé Marchand2, Yvan Grange3, Mouloud Yessaad4, Violaine Delannoy5, Camille Merienne2, Ian Soulairol6.1 Université Clermont Auvergne, CHU Clermont Ferrand, Clermont Auvergne INP, CNRS, ICCF, F-63000 Clermont-Ferrand, France.
2 Hospices Civils de Lyon - Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot
3 French National Agency for Medicines and Health Products Safety, ANSM, Laboratory Controls Division, 34740 Vendargues, France
4 CHU Clermont-Ferrand, Pôle Pharmacie, 63000 Clermont-Ferrand, France.
5 CHU Nîmes, Service Pharmacie, 30900 Nîmes
6 ICGM, Université Montpellier, CNRS, ENSCM, 34000 Montpellier, France
Validation of a visual inspection table with training and accreditation of operators for the control of sterile injectable preparations of curares
Zamani N.1, Albaut V.1, Maillard F.1, Delannoy V.1, Soulairol I1, 2.1 Pharmacie, Centre Hospitalier Universitaire Caremeau, Nîmes France
2 ICGM, Université de Montpellier, CNRS, ENSCM, Montpellier, France
Texture characterization of sodium thiosulfate hydrogels
J. Couturas1, N. Pecout2, J. Jost1, V. Guigonis3, M. Viana2, V. Ratsimbazafy11 Pharmacy Department, CHU Dupuytren, Limoges, France
2 Pharmaceutical Sciences Department, Faculty of Pharmacy, Limoges, France
3 University Hospital, Pediatry, Limoges, France
Simulating errors: a training tool for staff entering a cleanroom
Mathilde LOAËC1, Julie THIEC1, Amandine TAPON1, Virginie COGULET11 Pharmacie, CHRU de Brest, France
Evaluation of a novel rapid chemical contaminationdetection device: BD HD Check®
D. Montméat, M. Jobard, M.-L. Brandely-Piat, R. BatistaService de Pharmacie, GH Centre Université de Paris, Hôpital Cochin, AP-HP, France
Determination of the ideal protection of peristaltic pump while maintening the sterility of the isolateur
Aurélie BENOIT (1), Guillaume BOUGUEON (1, 2), Hélène BOULESTREAU (3), Sylvie CRESTO (3), Aude BERRONEAU (1), Sylvie CRAUSTE-MANCIET (1, 2), (1) Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
(2) ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
(3) Sanitary Department, Bordeaux university hospital (CHU de Bordeaux), France
Evaluation of radiopharmaceuticals sorption to 2 and 3 pieces syringes
C.Dupire 1, 2; P.Chennell3, 4 ; B.Pereira 5 ; V.Sautou 3, 4 ; S.Crauste-Manciet 1, 6 ; C.Morgat 1, 2, 71 - Pharmaceutical technology department, Bordeaux University Hospital, France
2 - Radiopharmacy department, Bordeaux University Hospital, France
3 - Pharmaceutical department, Clermont-Ferrand University Hospital, France
4 - ICCF, Clermont-Ferrand institute of chemistry, UMR 6296 CNRS, University of Clermont-Ferrand, France
5 - Department of Clinical Research and Innovation, Clermont-Ferrand University Hospital, France
6 - ARNA ChemBioPharm U1212 INSERM, UMR 5320 CNRS, University of Bordeaux, France
7 - INCIA, UMR 5287 CNRS, University of Bordeaux, France
COVID-19 essential medication: hospital production of rocuronium bromide 50mg/5mL
B. Dessane1, 2, J. Heloury1, A. Venet1, V. Servant1, JM. Bernadou1, F. Xuereb1, 3, Crauste-Manciet1, 21 Pharmaceutical Technology Department, Bordeaux University Hospital, France
2 ARNA ChemBioPharm U1212 INSERM – UMR 5320 CNRS, Bordeaux University, France
3 Univ. Bordeaux, Biologie des maladies cardiovasculaires, U1034 INSERM, F-33600 Pessac, France
Application of a new medicoeconomic evaluation tool for intravenous cytotoxic preparatoon
M.Dupré1, C.Cros1, A. Acramel1, C.Levenbruck1, A .Hurgon1, L.Escalup11 Unité de production des Anticancéreux, Institut Curie, 26 rue d’Ulm 75005 Paris
Optimization of a secured pharmaceutical control of intravenous chemotherapy. Elaboration of a decision tree model for every new referencement.
A. Tessier (1), L. Hassani (1), S.Ramos (1), H. Sadou Yaye (1), P. Tilleul (1) (2) A. Bellanger (1)(1) Pharmacie à usage intérieur du Centre Hospitalier Pitié-Salpétrière, AP-HP, France (2) Université Paris Descartes - France
Accurate prediction of the chemical stability of the pancuronium and its degradation products in injectable solution.
C. Merienne1, R. Guery1, T. Bourdais1, B. Lapras1, S. Filali1, C. Paillet2, F. Pirot11 Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon
2 Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon
UVC based decontamination of skin flora contaminated materials: a fast and complementary method to oxidant aerolization.
L. Bernollin1, A. Louguet1, B. Lapras1, C. Paillet2, C. Pivot2, S. Filali1, C. Merienne1, F. Pirot11 Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon
2 Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon
Assessment of psychosocial risks in a production unit
Soazic CADORET, Virginie RATTE, Corinne DELAIRE, Frédéric MARÇONCentre Hospitalier Universitaire d’Amiens-Picardie, Amiens, France
Anti-UV external packaging bags: are they really useful?
Jouini C, Claraz P, Benakouche S, Le Liboux J, Sabri A, Storme TPharmacotechnie pédiatrique, Pharmacie à usage intérieur, Hôpital universitaire mère-enfants Robert Debré, APHP.Nord, 48 Bld Sérurier 75019 Paris - France
Cyber-attack in an injectable chemotherapy reconstitution unit: what about the production in absence of prescription software
S.Vandewoestyne1, F.Théron1, F.Lacaud1, C.Gelas1, F.Vidal11 1Pharmacy of the Dax Hospital, France
Design of a self-assessment questionnaire on safe handling practices for hazardous drugs in Quebec
C. Delafoy1, J-F. Bussières1, 2, C. Tanguay11 Unité de Recherche en Pratique Pharmaceutique, Département de pharmacie, Centre hospitalier universitaire Sainte-Justine, Montréal, Québec, Canada;
2 Faculté de pharmacie, Université de Montréal, Montréal, Québec, Canada.
Bioburden determination for sterile process validation in the context of drug shortage during the COVID-19 pandemic
A. Cèbe1, A. Venet1, B. Dessane1, 2, V. Servant1, J. Héloury1, S. Crauste-Manciet1, 21 Pharmaceutical Technology Department, Bordeaux University Hospital, France
2 ARNA Laboratory ChemBioPharm U1212 INSERM - UMR 5320 CNRS, Bordeaux University, France
Qualification of the Noodis® robot for liquid oral medications doses filling and tapering
F. Lagrange1 J Lagrange21 Pierre Lôo and Henry Dunant Hospital Pharmacies, Nièvre Hospitals Group, 51, rue des Hostelleries, BP 137, 58400 La Charité-sur-Loire, France
2 Epitech Paris, France and CSULB, Long Beach, CA
E-Posters - Session A
Analytical and gravimetric qualification of a chemotherapy production robot
Charly Paillat 1, Maïté Sangnier1, Laura Mérieux1, Ilhem Malagouen1, Guillaume Binson1, Isabelle Princet1, Anne-Sophie Haverlan1, Sara Binson1
1 CHU Poitiers, Pharmacy Department, 2 rue de la Milétrie, 86000 Poitiers, France Pre-analytic optimization of API assays in compounded oral suspensions for pediatrics L. Bourgue, L. Gayard et M. Ben Reguiga
Department of Pharmacy - Mayotte Hospital Center - 97600 Mayotte (France) Qualification of a mixer: how to obtain the homogeneity of semi-solid preparations for skin application (SSPSA) JM des Courtils, AG Toulon-Veber, J. Forget, S. Provot
Hôpital Clocheville, CHRU Tours, France
Qualification of a mixer: how to obtain the homogeneity of a mixture of powders? JM des Courtils, AG Toulon-Veber, J. Forget, S. Provot
Hôpital Clocheville, CHRU Tours, France
Development and validation of an assay method for the determination of pyrimethamine in an oral suspension by HPLC-UV S. Muhammad, Z. Ribier, G. Benoit, J. Bordenave
Hôpital Armand Trousseau, Paris, France Rapid, quantitative and qualitative control of oxaliplatin in G5% using a separative HPLC method Guillaume HILY (1), Jean-Marc BERNADOU(1), Maïté SANGNIER(1), Guillaume BOUGUEON(1,2), Fabien XUEREB(1,3), Aude BERRONEAU(1), Sylvie CRAUSTE-MANCIET(1,2)
1 Pharmaceutical Technology Department, Bordeaux University Hospital, France
2 ARNA ChemBioPharm U1212 INSERM – UMR 5320 CNRS, Bordeaux University, France
3 Univ. Bordeaux, INSERM, Biologie des maladies cardiovasculaires, U1034, F-33600 Pessac, France
Accuracy and repeatability, on a given day, of centralized preparation of Covid-19 vaccines in a vaccination centre. DUPART Anne-Laure1, MENNESSON-LANDEMARE Chloé1, RUST Cécile1, FRANCOIS David2, LOPEZ Marlène3, BERANGER Cyrille3, MULLOT Jean-Ulrich2
1 Ecoles Militaires de Santé de Lyon Bron, 331 Avenue Général de Gaulle – 69500 BRON - FRANCE
2 LASEM de Toulon – Base Navale de TOULON - FRANCE
3 HIA Sainte Anne, 2 Boulevard Sainte Anne - 83800 TOULON - FRANCE
Harmonisation of pharmaceutical release practices for injectable chemotherapy preparations after analytical control M. Beaurain1, A. Teixeira1, A. Baudouin1, F. Ranchon1, C. Rioufol1, N. Vantard1
1 : Oncology Clinical Pharmacy Unit, Pharmacy, Lyon South Hospital Group, Hospices Civils de Lyon
Digital video control at the Centralized Unit of Chemotherapy Preparation: total security of the preparation process? L. Josse(1), H. Cadart(1), A.Bianchi(1)
(1) Pharmacy Unit, Centre Hospitalier Intercommunal Nord Ardennes, Charleville Mézières, 45 avenue de Manchester, 08000 Charleville Mézières, France Qualification of a new Cytocontrol® balance prototype under isolator Hugo Palisson1, Alexandre Acramel1,2, Justine Duplan1, Marya Mpandzou-Kongo1, Chloé Levenbruck1, Cyrille Cros1, Audrey Hurgon1, Laurence Escalup1
1 Département de Pharmacie, Institut Curie, Paris, France
2 Université de Paris, CiTCoM, CNRS UMR 8038, INSERM U 1268, Paris, France
Analytical control of 5-fluorouracil dispensers, finally possible? G. Croux1, L. Barty1, S. Perreau, N. Vaillant1, I. Madelaine, H. Sauvageon, N. Jourdan1
1 Pharmacie à usage intérieur, Hôpital St Louis, 1 Avenue Claude Vellefaux, 75010 Paris
1 CHU Poitiers, Pharmacy Department, 2 rue de la Milétrie, 86000 Poitiers, France Pre-analytic optimization of API assays in compounded oral suspensions for pediatrics L. Bourgue, L. Gayard et M. Ben Reguiga
Department of Pharmacy - Mayotte Hospital Center - 97600 Mayotte (France) Qualification of a mixer: how to obtain the homogeneity of semi-solid preparations for skin application (SSPSA) JM des Courtils, AG Toulon-Veber, J. Forget, S. Provot
Hôpital Clocheville, CHRU Tours, France
Qualification of a mixer: how to obtain the homogeneity of a mixture of powders? JM des Courtils, AG Toulon-Veber, J. Forget, S. Provot
Hôpital Clocheville, CHRU Tours, France
Development and validation of an assay method for the determination of pyrimethamine in an oral suspension by HPLC-UV S. Muhammad, Z. Ribier, G. Benoit, J. Bordenave
Hôpital Armand Trousseau, Paris, France Rapid, quantitative and qualitative control of oxaliplatin in G5% using a separative HPLC method Guillaume HILY (1), Jean-Marc BERNADOU(1), Maïté SANGNIER(1), Guillaume BOUGUEON(1,2), Fabien XUEREB(1,3), Aude BERRONEAU(1), Sylvie CRAUSTE-MANCIET(1,2)
1 Pharmaceutical Technology Department, Bordeaux University Hospital, France
2 ARNA ChemBioPharm U1212 INSERM – UMR 5320 CNRS, Bordeaux University, France
3 Univ. Bordeaux, INSERM, Biologie des maladies cardiovasculaires, U1034, F-33600 Pessac, France
Accuracy and repeatability, on a given day, of centralized preparation of Covid-19 vaccines in a vaccination centre. DUPART Anne-Laure1, MENNESSON-LANDEMARE Chloé1, RUST Cécile1, FRANCOIS David2, LOPEZ Marlène3, BERANGER Cyrille3, MULLOT Jean-Ulrich2
1 Ecoles Militaires de Santé de Lyon Bron, 331 Avenue Général de Gaulle – 69500 BRON - FRANCE
2 LASEM de Toulon – Base Navale de TOULON - FRANCE
3 HIA Sainte Anne, 2 Boulevard Sainte Anne - 83800 TOULON - FRANCE
Harmonisation of pharmaceutical release practices for injectable chemotherapy preparations after analytical control M. Beaurain1, A. Teixeira1, A. Baudouin1, F. Ranchon1, C. Rioufol1, N. Vantard1
1 : Oncology Clinical Pharmacy Unit, Pharmacy, Lyon South Hospital Group, Hospices Civils de Lyon
Digital video control at the Centralized Unit of Chemotherapy Preparation: total security of the preparation process? L. Josse(1), H. Cadart(1), A.Bianchi(1)
(1) Pharmacy Unit, Centre Hospitalier Intercommunal Nord Ardennes, Charleville Mézières, 45 avenue de Manchester, 08000 Charleville Mézières, France Qualification of a new Cytocontrol® balance prototype under isolator Hugo Palisson1, Alexandre Acramel1,2, Justine Duplan1, Marya Mpandzou-Kongo1, Chloé Levenbruck1, Cyrille Cros1, Audrey Hurgon1, Laurence Escalup1
1 Département de Pharmacie, Institut Curie, Paris, France
2 Université de Paris, CiTCoM, CNRS UMR 8038, INSERM U 1268, Paris, France
Analytical control of 5-fluorouracil dispensers, finally possible? G. Croux1, L. Barty1, S. Perreau, N. Vaillant1, I. Madelaine, H. Sauvageon, N. Jourdan1
1 Pharmacie à usage intérieur, Hôpital St Louis, 1 Avenue Claude Vellefaux, 75010 Paris
E-Posters - Session B
Feedback on nominative parenteral lipids-vitamins admixtures production using LOGIPREN® software
V. Lebreton, F. Gaume, A. Ifrah, A. Bourges, S. Letourneux, S. Vrignaud
Pharmacie Centrale CHU Angers, 4 rue Larrey, 49933 Angers Cedex 9
Vaccination against COVID-19: feedback on the reconstitution of doses of Comirnaty® vaccine C. Biasolo1, M-A. Gratelle1, C. Bédoucha1, Jean-Pierre Pereira2, R. Dulin1, M. Gayral1, A-C. Marion1
(1) : Pharmacy of the Libourne Hospital Center
(2) : IT services department
Implementation of dose-banding in a pharmaceutical Chemotherapies Preparation Unit: Results after 3 years M.Bobillot1, E.Coget1, C.Gillet1, P.Brouard1, A.Gahbiche1, C.Cousin1
(1) CHU de Nîmes, Unité de Préparation Oncologique, France
Production of Comirnaty® vaccine doses by the pharmacy: how to organize? L. Champmartin, S. Huet, E. Nevado, J. Couturas, B. Crosio, Y. Fromage, K. Itoua-Gassaye, JP. Lebon, E. Montanard, V. Perrier, M. Pradera, O. Dauriac, S. Lopez, H. Carpenet, V. Ratsimbazafy, A. Marie-Daragon, G. Maillan
Pharmacy, University Hospital Center Dupuytren, 2 avenue Martin Luther King, 87000 Limoges National survey on the management of urgent requests for injectable chemotherapy preparations outside of chemotherapy reconstitution units (CRU) working hours L. Champmartin, E. Nevado, S. Huet, G. Maillan
Pharmacy, University Hospital Center Dupuytren, 2 avenue Martin Luther King, 87000 Limoges
Design of assistance tools to manage robotic production with Kiro Oncology® A. Mouradian1, M. Jobard2, M.-L. Brandely-Piat1, R. Batista1,2 1- Unité de Préparations Stériles Ophtalmologiques et Oncologiques, 2- Unité d’Assurance Qualité, Service de Pharmacie clinique, GH Centre Université de Paris, AP-HP, Hôpital Cochin, 27 rue du faubourg St Jacques, 75014 Paris, France
Medical-economic study and practical assessment of standard sleeves-gloves (GMS) versus secure connector ring (BCS) sleeves-gloves B. Berton1, E. Voinet1, M. Pellissier 1, R. Veillet 1, S. Occhipinti 1, E. Goiffon 1, R. Chevrier 1
1 Unité de pharmacie clinique oncologique, Centre de Lutte Contre le Cancer - Jean Perrin, 58 Rue Montalembert, 63011 Clermont-Ferrand Cedex1, FRANCE
Comparative qualitative study between specialties of azacitidine available in France Pacqueu L. 1, Beausir A.1, Nachon P.1, Le Joubioux A.1
1 CH Lens, France Adaptation of hospital aseptic processes to face national shortage of curare C. Navaud1, G. Bouguéon1,2, J-M Bernadou1, B. Dessane1,2, A. Venet1, J. Heloury1, V. Servant1, S. Cresto4, H. Boulestreau4, F. Xuereb.1,3, A. Berroneau1, S. Crauste-Manciet1,2
1- Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
2- ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
3- Pharmacokinetics and PK/PD Group, INSERM 1034, University of Bordeaux, France
4- Hospital Hygiene Service, Bordeaux university hospital (CHU de Bordeaux), France
What organisation is needed to ensure the safe preparation of on-call chemotherapy? Sonia Martelli1, Emilie Seguin1, Antoine Bruneau1 Clara Balouzet2, Anne-Pauline Thivilliers3,
Marion Jobard4, Marie-Laure Brandely-Piat1, Rui Batista1,2,3,4 1-Unité de Préparations Stériles Ophtalmologiques et Oncologiques, 2- Unité de Radiopharmacie, 3- Unité de Nutrition Parentérale Pédiatrique, 4- Unité d’Assurance Qualité, Service de Pharmacie, GH Centre Université de Paris, AP-HP Hôpital Cochin, 27 rue du faubourg St Jacques, 75014 Paris, France
Evaluation of the Romeo® handling aid and its impact on the prevention of musculoskeletal disorders Vaillant M. 1 ; Friou M. 1 ; Lafay M. 1; Escalup L. 1
1 : Pharmacy, Institut Curie site Saint Cloud, 35 rue Dailly, 92210 Saint Cloud, France
Preparation of 5-Fluorouracil elastomeric devices : does Facilimix® make life easier ? Emilie Seguin, Sonia Martelli, Antoine Bruneau, Aline Mouradian, Marie-Laure Brandely-Piat, Rui Batista Unité de préparations Stériles Ophtalmologiques et Oncologiques, Service de Pharmacie, Hôpital Cochin, Groupe Hospitalier Centre Université de Paris, AP-HP, 27 rue du Faubourg St Jacques, 75014 Paris, France
Conducting a change in practice: new procedure for the preparation of portable antibiotic dispensers C.Villié(1); C.Duquenne(1) ; M. Durand(1) ; R.Mazet(1) ; MD. Desruet(1,2) ; P. Bedouch(1,3)
1. Department of Pharmacy, Grenoble University, F-38000, Grenoble France 2. Laboratory of Bioclinic Radiopharmaceutics, Grenoble University, Inserm, CHU Grenoble, France 3. University Grenoble Alpes, CNRS, TIMC-IMAG UMR 5525, ThEMAS, F-38000, Grenoble, France
Pharmacie Centrale CHU Angers, 4 rue Larrey, 49933 Angers Cedex 9
Vaccination against COVID-19: feedback on the reconstitution of doses of Comirnaty® vaccine C. Biasolo1, M-A. Gratelle1, C. Bédoucha1, Jean-Pierre Pereira2, R. Dulin1, M. Gayral1, A-C. Marion1
(1) : Pharmacy of the Libourne Hospital Center
(2) : IT services department
Implementation of dose-banding in a pharmaceutical Chemotherapies Preparation Unit: Results after 3 years M.Bobillot1, E.Coget1, C.Gillet1, P.Brouard1, A.Gahbiche1, C.Cousin1
(1) CHU de Nîmes, Unité de Préparation Oncologique, France
Production of Comirnaty® vaccine doses by the pharmacy: how to organize? L. Champmartin, S. Huet, E. Nevado, J. Couturas, B. Crosio, Y. Fromage, K. Itoua-Gassaye, JP. Lebon, E. Montanard, V. Perrier, M. Pradera, O. Dauriac, S. Lopez, H. Carpenet, V. Ratsimbazafy, A. Marie-Daragon, G. Maillan
Pharmacy, University Hospital Center Dupuytren, 2 avenue Martin Luther King, 87000 Limoges National survey on the management of urgent requests for injectable chemotherapy preparations outside of chemotherapy reconstitution units (CRU) working hours L. Champmartin, E. Nevado, S. Huet, G. Maillan
Pharmacy, University Hospital Center Dupuytren, 2 avenue Martin Luther King, 87000 Limoges
Design of assistance tools to manage robotic production with Kiro Oncology® A. Mouradian1, M. Jobard2, M.-L. Brandely-Piat1, R. Batista1,2 1- Unité de Préparations Stériles Ophtalmologiques et Oncologiques, 2- Unité d’Assurance Qualité, Service de Pharmacie clinique, GH Centre Université de Paris, AP-HP, Hôpital Cochin, 27 rue du faubourg St Jacques, 75014 Paris, France
Medical-economic study and practical assessment of standard sleeves-gloves (GMS) versus secure connector ring (BCS) sleeves-gloves B. Berton1, E. Voinet1, M. Pellissier 1, R. Veillet 1, S. Occhipinti 1, E. Goiffon 1, R. Chevrier 1
1 Unité de pharmacie clinique oncologique, Centre de Lutte Contre le Cancer - Jean Perrin, 58 Rue Montalembert, 63011 Clermont-Ferrand Cedex1, FRANCE
Comparative qualitative study between specialties of azacitidine available in France Pacqueu L. 1, Beausir A.1, Nachon P.1, Le Joubioux A.1
1 CH Lens, France Adaptation of hospital aseptic processes to face national shortage of curare C. Navaud1, G. Bouguéon1,2, J-M Bernadou1, B. Dessane1,2, A. Venet1, J. Heloury1, V. Servant1, S. Cresto4, H. Boulestreau4, F. Xuereb.1,3, A. Berroneau1, S. Crauste-Manciet1,2
1- Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
2- ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
3- Pharmacokinetics and PK/PD Group, INSERM 1034, University of Bordeaux, France
4- Hospital Hygiene Service, Bordeaux university hospital (CHU de Bordeaux), France
What organisation is needed to ensure the safe preparation of on-call chemotherapy? Sonia Martelli1, Emilie Seguin1, Antoine Bruneau1 Clara Balouzet2, Anne-Pauline Thivilliers3,
Marion Jobard4, Marie-Laure Brandely-Piat1, Rui Batista1,2,3,4 1-Unité de Préparations Stériles Ophtalmologiques et Oncologiques, 2- Unité de Radiopharmacie, 3- Unité de Nutrition Parentérale Pédiatrique, 4- Unité d’Assurance Qualité, Service de Pharmacie, GH Centre Université de Paris, AP-HP Hôpital Cochin, 27 rue du faubourg St Jacques, 75014 Paris, France
Evaluation of the Romeo® handling aid and its impact on the prevention of musculoskeletal disorders Vaillant M. 1 ; Friou M. 1 ; Lafay M. 1; Escalup L. 1
1 : Pharmacy, Institut Curie site Saint Cloud, 35 rue Dailly, 92210 Saint Cloud, France
Preparation of 5-Fluorouracil elastomeric devices : does Facilimix® make life easier ? Emilie Seguin, Sonia Martelli, Antoine Bruneau, Aline Mouradian, Marie-Laure Brandely-Piat, Rui Batista Unité de préparations Stériles Ophtalmologiques et Oncologiques, Service de Pharmacie, Hôpital Cochin, Groupe Hospitalier Centre Université de Paris, AP-HP, 27 rue du Faubourg St Jacques, 75014 Paris, France
Conducting a change in practice: new procedure for the preparation of portable antibiotic dispensers C.Villié(1); C.Duquenne(1) ; M. Durand(1) ; R.Mazet(1) ; MD. Desruet(1,2) ; P. Bedouch(1,3)
1. Department of Pharmacy, Grenoble University, F-38000, Grenoble France 2. Laboratory of Bioclinic Radiopharmaceutics, Grenoble University, Inserm, CHU Grenoble, France 3. University Grenoble Alpes, CNRS, TIMC-IMAG UMR 5525, ThEMAS, F-38000, Grenoble, France
E-Posters - Session C
Daratumumab subcutaneous formulation : impact of its stability period on a dispensation and administration process
Mbouyou A.1, Kerr G.1, Lecoutre A.1, Courtin J.1, Pinturaud M.1, Vasseur M.1,2, Odou P.1,2
1 Institut de Pharmacie, CHU de Lille, Lille, France
2 Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA), Centre Hospitalier Universitaire de Lille, Lille, France
FMECA (Failure Modes, Effects and Criticality Analysis) in manufacturing pediatric individualized parenteral nutrition (IPN) bags process: 4 years review of corrective actions. A-G Toulon-Veber, J-M Des Courtils, S. Mitreski, J. Forget, S. Provôt, P. Meunier
Pharmacy - Clocheville Hospital, CHRU of Tours, 49 Bd Béranger, 37044 Tours CEDEX - France
Development and physico-chemical stability study of an oral liquid form of letermovir for pediatric use Sabri A, Bari L, Vasseur V, Le Liboux J, Benakouche S, Bourdon O, Storme T
Pharmacotechnie pédiatrique, Pharmacie à usage intérieur, Hôpital universitaire mère-enfants Robert Debré, APHP.Nord, 48 Bld Sérurier 75019 Paris – France Physicochemical and microbiological stability of Spironolactone oral suspension without potentially harmful excipient Maxime Petit 1, Sonia Mitreski 1, Julie Forget 1, Hassan Allouchi 2, Elodie Baticle 3, Eric Bailly 4, Stéphanie Provot 1, Xavier Pourrat 1
1. Pharmacy, CHRU Tours, France
2. Control Laboratory, CHRU Tours, France
3. Bacteriology and Hospital Hygiene Unit, CHRU Tours
4. Parasitology, Mycology and Tropical Medicine Laboratory, CHRU Tours, France Preliminary study for a microbiological stability study: Microbiological integrity test Clément Hamelin1, Gautier Dozias1, Gaëlle Larhantec1, Virginie Cogulet1
1 Pharmacy, CHU de Brest
Physical stability of 0.02% chlorhexidine digluconate eye drops in 5% glucose or phosphate buffer at refrigerated and room Erwin Lenglet1, Manon Gareau1, Léa Savio1, Mathieu Wasiak1, Yassine Bouattour1,2, Valérie Sautou1,2, Philip Chennell1,2
1 : CHU Clermont-Ferrand, Pôle Pharmacie, 63000 Clermont-Ferrand, France
2 : Université Clermont Auvergne, CHU Clermont-Ferrand, CNRS, SIGMA Clermont-Ferrand, ICCF, 63000 Clermont-Ferrand, France Risk assessment of pharmaceutical preparations control process by FMECA methodology Léa Savio1, Lucile Durroux1, Laurent de Brito1, Yassine Bouattour12, Valérie Sautou2, Philip Chennell2
1 CHU Clermont-Ferrand, Pôle Pharmacie, 63000 Clermont-Ferrand, France.
2 Université Clermont Auvergne, CHU Clermont-Ferrand, CNRS, SIGMA Clermont-Ferrand, ICCF, 63000 Clermont-Ferrand, France.
Impact of temperature on the physico-chemical stability of Azacitidine Zentiva 25 mg/ml suspensions packaged in polypropylene syringes V.Vieillard, W. Saeed, G. Le Guyader, M.Paul
Pharmacy Department, CHU Henri Mondor, 51 Avenue du Maréchal De Lattre de Tassigny 94000 Créteil, France
Design and stability study of oral capsules and suspension of riboflavin for the treatment of metabolic disease P.Gohier1, B. Dessane1,2, J-M. Bernadou1, H. Boulestreau2, F. Xuereb1,4, A. Venet1, S. Crauste-Manciet1,3
1 Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
2 Infection Control Unit, Bordeaux university hospital (CHU de Bordeaux), France
3 ARNA ChemBioPharm U1212 INSERM – UMR 5320 CNRS, Bordeaux University, France
4 Univ. Bordeaux, INSERM, Biologie des maladies cardiovasculaires, U1034, F-33600 Pessac, France
Study of the addition of L-Carnitine in pediatric parenteral nutrition binary mixtures S. Renaud, N. Chouaou, D. Reitter, T. Liautaud, L. Sedrati, S. Coulon; Pharmacie à usage Intérieur du Grand Hôpital de l’Est Francilien, site de Marne-La-Vallée, 2-4 cours de la Gondoire, 77600 Jossigny, France Physicochemical stability of piperacillin/tazobactam in syringe and elastomeric device for continuous administration in critical care and at home Loeuille G.1, Vigneron J. 1,4, D’Huart E. 1,4, Charmillon A. 2, Demore B. 1,3,4
1 Pharmacie, CHRU de Nancy, Allée du Morvan, 54511 Vandœuvre-lès-Nancy, France
2 Equipe transversale d’infectiologie, CHRU de Nancy, Allée du Morvan, 54511 Vandœuvre-lès-Nancy, France
3 Université de Lorraine, EA 4360 APEMAC, Nancy, France.
4 Infostab, Association à but non lucratif, 54180 Heillecourt France
1 Institut de Pharmacie, CHU de Lille, Lille, France
2 Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA), Centre Hospitalier Universitaire de Lille, Lille, France
FMECA (Failure Modes, Effects and Criticality Analysis) in manufacturing pediatric individualized parenteral nutrition (IPN) bags process: 4 years review of corrective actions. A-G Toulon-Veber, J-M Des Courtils, S. Mitreski, J. Forget, S. Provôt, P. Meunier
Pharmacy - Clocheville Hospital, CHRU of Tours, 49 Bd Béranger, 37044 Tours CEDEX - France
Development and physico-chemical stability study of an oral liquid form of letermovir for pediatric use Sabri A, Bari L, Vasseur V, Le Liboux J, Benakouche S, Bourdon O, Storme T
Pharmacotechnie pédiatrique, Pharmacie à usage intérieur, Hôpital universitaire mère-enfants Robert Debré, APHP.Nord, 48 Bld Sérurier 75019 Paris – France Physicochemical and microbiological stability of Spironolactone oral suspension without potentially harmful excipient Maxime Petit 1, Sonia Mitreski 1, Julie Forget 1, Hassan Allouchi 2, Elodie Baticle 3, Eric Bailly 4, Stéphanie Provot 1, Xavier Pourrat 1
1. Pharmacy, CHRU Tours, France
2. Control Laboratory, CHRU Tours, France
3. Bacteriology and Hospital Hygiene Unit, CHRU Tours
4. Parasitology, Mycology and Tropical Medicine Laboratory, CHRU Tours, France Preliminary study for a microbiological stability study: Microbiological integrity test Clément Hamelin1, Gautier Dozias1, Gaëlle Larhantec1, Virginie Cogulet1
1 Pharmacy, CHU de Brest
Physical stability of 0.02% chlorhexidine digluconate eye drops in 5% glucose or phosphate buffer at refrigerated and room Erwin Lenglet1, Manon Gareau1, Léa Savio1, Mathieu Wasiak1, Yassine Bouattour1,2, Valérie Sautou1,2, Philip Chennell1,2
1 : CHU Clermont-Ferrand, Pôle Pharmacie, 63000 Clermont-Ferrand, France
2 : Université Clermont Auvergne, CHU Clermont-Ferrand, CNRS, SIGMA Clermont-Ferrand, ICCF, 63000 Clermont-Ferrand, France Risk assessment of pharmaceutical preparations control process by FMECA methodology Léa Savio1, Lucile Durroux1, Laurent de Brito1, Yassine Bouattour12, Valérie Sautou2, Philip Chennell2
1 CHU Clermont-Ferrand, Pôle Pharmacie, 63000 Clermont-Ferrand, France.
2 Université Clermont Auvergne, CHU Clermont-Ferrand, CNRS, SIGMA Clermont-Ferrand, ICCF, 63000 Clermont-Ferrand, France.
Impact of temperature on the physico-chemical stability of Azacitidine Zentiva 25 mg/ml suspensions packaged in polypropylene syringes V.Vieillard, W. Saeed, G. Le Guyader, M.Paul
Pharmacy Department, CHU Henri Mondor, 51 Avenue du Maréchal De Lattre de Tassigny 94000 Créteil, France
Design and stability study of oral capsules and suspension of riboflavin for the treatment of metabolic disease P.Gohier1, B. Dessane1,2, J-M. Bernadou1, H. Boulestreau2, F. Xuereb1,4, A. Venet1, S. Crauste-Manciet1,3
1 Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
2 Infection Control Unit, Bordeaux university hospital (CHU de Bordeaux), France
3 ARNA ChemBioPharm U1212 INSERM – UMR 5320 CNRS, Bordeaux University, France
4 Univ. Bordeaux, INSERM, Biologie des maladies cardiovasculaires, U1034, F-33600 Pessac, France
Study of the addition of L-Carnitine in pediatric parenteral nutrition binary mixtures S. Renaud, N. Chouaou, D. Reitter, T. Liautaud, L. Sedrati, S. Coulon; Pharmacie à usage Intérieur du Grand Hôpital de l’Est Francilien, site de Marne-La-Vallée, 2-4 cours de la Gondoire, 77600 Jossigny, France Physicochemical stability of piperacillin/tazobactam in syringe and elastomeric device for continuous administration in critical care and at home Loeuille G.1, Vigneron J. 1,4, D’Huart E. 1,4, Charmillon A. 2, Demore B. 1,3,4
1 Pharmacie, CHRU de Nancy, Allée du Morvan, 54511 Vandœuvre-lès-Nancy, France
2 Equipe transversale d’infectiologie, CHRU de Nancy, Allée du Morvan, 54511 Vandœuvre-lès-Nancy, France
3 Université de Lorraine, EA 4360 APEMAC, Nancy, France.
4 Infostab, Association à but non lucratif, 54180 Heillecourt France
E-Posters - Session D
Premature deterioration of a transfer isolator: qualification of a sterilisation time in anticipation of replacing the damaged part.
Stéphanie Tawil1,} Manon Etis1, Françoise Giraudier1, Marion Lefebvre1, Françoise Cabrera1
1 Pôle Pharmaceutique, CH de Roanne, France Surface monitoring in isolators: feedback on a national survey of practices Chloé DELAUNAY1, Laura GIAMBERINI1, Emmanuelle OLIVIER1, Nicolas CORMIER11
1 CHU de Nantes Hôtel-Dieu, Service Pharmacie, 1 Pl. Alexis Ricordeau, 44093 Nantes
Microbiological qualification of an automatic compounding system for the production of chemotherapy Philippine Marque1, Ilhem Malagouen1, Isabelle Princet1, Sara Molignier1, Anne-Sophie Haverlan1
1 Pharmacy, CHU Poitiers, France
Qualification of a robotic system for antiblastic drug compounding: evaluation of the chemical contamination with a fluorescein solution Laura Fabre1, Clément Cappelier1, Ilhem Malagouen1, Isabelle Princet1, Anne-Sophie Haverlan1, Sara Binson1
1 Pharmacie à usage intérieur, CHU de Poitiers
Media fill test: concrete implementation Mélissa Boudia1, Thomas Boccassini1, Sylvie Gombault2, Alice Watfeh2, Serge Fotso3, Zoé Leguay3, Véronique Priou3, Isabelle Hermelin-Jobet3
1 Pharmaceutical resident, 2 Pharmaceutical assistant, 3 Pharmacists, CHR Orléans, France
Implementation of measures to reduce chemical contamination by cytotoxics in a centralised Chemotherapy Reconstitution Unit: are they effective? A. Ifrah, E. Balduini, A. Lebreton, L. Le Quay
Pharmacie, CHU Angers, 4 rue Larrey, 49933 Angers Cedex 9, France
Risk mapping within a cytotoxic preparation unit HAINAUT Marc-Antoine1, FILLATRE Adrien1, ABDAOUI Ahmed1, SAINT-GERMAIN Pierre1, HOUBERT Audrey1 1 Centre hospitalier de Saint-Quentin, 1 Avenue Michel de l’Hospital BP 608, 02321 Saint-Quentin – France Membrane filtration sterility assay: suitability test for amikacin eye drops 50 mg/mL F. Saïag1, V. Lebreton1,2, A. Bourges1, M. Petit1, S. Vrignaud1
1 Pharmacy, University Hospital of Angers, France
2 MINT laboratory, INSERM U1066-CNRS 6021, Angers, France Development and validation of sterility test method by membrane filtration of ceftazidime 5% eye drops Nicolas GUILLARD1, Chloé DELAUNAY1, Emmanuelle OLIVIER1, Nicolas CORMIER1
1 CHU de Nantes Hôtel-Dieu, Service Pharmacie, 1 Pl. Alexis Ricordeau, 44093 Nantes, France
Exposure to cytotoxics: a wide scale measurement campaign in a hospital Marie Robert1, Eva Coulpier1, Elisabeth Lheritier1.
1 Centre Hospitalier de Dieppe, Pharmacie, Avenue Pasteur, 76202 Dieppe. France
Evaluation of surface contamination by cytotoxic drugs (CD) in the centralized cytotoxic reconstitution unit (URCC) Adèle Bruyere1, Camille Sereni1, Fabienne Morey1, Baptiste Mauguen1
1 : Pharmacie, Centre Hospitalier de Bourg-en-Bresse, 900, route de Paris - CS 90401, 01012 BOURG EN BRESSE cedex FRANCE
Risk analysis to support the implementation of Dose Banding circuit in Cancer Centre Khevin Itoua-Gassaye1, Mallory Friou1, Marion Lafay1, Adeline Cordary2, Laurence Escalup1
1 Pharmacy Department,
2 Quality-Risk Management Department, Institut Curie, 35 Rue Dailly, 92210 Saint-Cloud
Establishment of a community of practice on the safe handling of hazardous drugs in Quebec C. Delafoy1, J-F. Bussières1,2, C. Tanguay1
1 Unité de Recherche en Pratique Pharmaceutique, Département de pharmacie, Centre hospitalier universitaire Sainte-Justine, Montréal, Québec, Canada
2 Faculté de pharmacie, Université de Montréal, Montréal, Québec, Canada
1 Pôle Pharmaceutique, CH de Roanne, France Surface monitoring in isolators: feedback on a national survey of practices Chloé DELAUNAY1, Laura GIAMBERINI1, Emmanuelle OLIVIER1, Nicolas CORMIER11
1 CHU de Nantes Hôtel-Dieu, Service Pharmacie, 1 Pl. Alexis Ricordeau, 44093 Nantes
Microbiological qualification of an automatic compounding system for the production of chemotherapy Philippine Marque1, Ilhem Malagouen1, Isabelle Princet1, Sara Molignier1, Anne-Sophie Haverlan1
1 Pharmacy, CHU Poitiers, France
Qualification of a robotic system for antiblastic drug compounding: evaluation of the chemical contamination with a fluorescein solution Laura Fabre1, Clément Cappelier1, Ilhem Malagouen1, Isabelle Princet1, Anne-Sophie Haverlan1, Sara Binson1
1 Pharmacie à usage intérieur, CHU de Poitiers
Media fill test: concrete implementation Mélissa Boudia1, Thomas Boccassini1, Sylvie Gombault2, Alice Watfeh2, Serge Fotso3, Zoé Leguay3, Véronique Priou3, Isabelle Hermelin-Jobet3
1 Pharmaceutical resident, 2 Pharmaceutical assistant, 3 Pharmacists, CHR Orléans, France
Implementation of measures to reduce chemical contamination by cytotoxics in a centralised Chemotherapy Reconstitution Unit: are they effective? A. Ifrah, E. Balduini, A. Lebreton, L. Le Quay
Pharmacie, CHU Angers, 4 rue Larrey, 49933 Angers Cedex 9, France
Risk mapping within a cytotoxic preparation unit HAINAUT Marc-Antoine1, FILLATRE Adrien1, ABDAOUI Ahmed1, SAINT-GERMAIN Pierre1, HOUBERT Audrey1 1 Centre hospitalier de Saint-Quentin, 1 Avenue Michel de l’Hospital BP 608, 02321 Saint-Quentin – France Membrane filtration sterility assay: suitability test for amikacin eye drops 50 mg/mL F. Saïag1, V. Lebreton1,2, A. Bourges1, M. Petit1, S. Vrignaud1
1 Pharmacy, University Hospital of Angers, France
2 MINT laboratory, INSERM U1066-CNRS 6021, Angers, France Development and validation of sterility test method by membrane filtration of ceftazidime 5% eye drops Nicolas GUILLARD1, Chloé DELAUNAY1, Emmanuelle OLIVIER1, Nicolas CORMIER1
1 CHU de Nantes Hôtel-Dieu, Service Pharmacie, 1 Pl. Alexis Ricordeau, 44093 Nantes, France
Exposure to cytotoxics: a wide scale measurement campaign in a hospital Marie Robert1, Eva Coulpier1, Elisabeth Lheritier1.
1 Centre Hospitalier de Dieppe, Pharmacie, Avenue Pasteur, 76202 Dieppe. France
Evaluation of surface contamination by cytotoxic drugs (CD) in the centralized cytotoxic reconstitution unit (URCC) Adèle Bruyere1, Camille Sereni1, Fabienne Morey1, Baptiste Mauguen1
1 : Pharmacie, Centre Hospitalier de Bourg-en-Bresse, 900, route de Paris - CS 90401, 01012 BOURG EN BRESSE cedex FRANCE
Risk analysis to support the implementation of Dose Banding circuit in Cancer Centre Khevin Itoua-Gassaye1, Mallory Friou1, Marion Lafay1, Adeline Cordary2, Laurence Escalup1
1 Pharmacy Department,
2 Quality-Risk Management Department, Institut Curie, 35 Rue Dailly, 92210 Saint-Cloud
Establishment of a community of practice on the safe handling of hazardous drugs in Quebec C. Delafoy1, J-F. Bussières1,2, C. Tanguay1
1 Unité de Recherche en Pratique Pharmaceutique, Département de pharmacie, Centre hospitalier universitaire Sainte-Justine, Montréal, Québec, Canada
2 Faculté de pharmacie, Université de Montréal, Montréal, Québec, Canada
E-Posters - Session E
Modérators
Dr Y. Huon, Liège
Dr P. Rohrbach, CH Verdun Comparative study of the different Closed System Transfer Devices available in France for the preparation of injectable immunotherapies. Albaut V.1, Brobst M.1, Colliat F.2, Castel D.1
1 Pharmacie, Centre Hospitalier Alès Cévennes, Alès, France
2 Pharmacie, Hôpitaux du bassin Thau, Sète, France
Sterilization of infusion bags : is removing the secondary packaging safe? AF Dumas1, R Pechaud1, M Rannou1, I Dufrene1, H Hida1
1 Service Pharmacie, Centre Hospitalier de Valence
The Errors Tray: a simulation tool for evaluating professional practices in a chemotherapy production unit Tristan Rubin1, Clément Cappelier1, Florine Chollet1, Sonia Mitreski1, Victor Massot1, Chloé Plichon1, Virginie Andre1, Xavier Pourrat2
1 Oncological Clinical Biopharmacy Unit, CHRU Tours, France
2 Trousseau Pharmacy, CHRU Tours, France
Validation of a new medical device devoted for autologous serum eye drops sterile preparation J. Heloury1, B. Dessane1,2, O. Vergnaud1, A. Venet1, V. Servant1, S. Crauste-Manciet1,2
1 Pharmaceutical Technology Department, Bordeaux University Hospital, France
2 ARNA ChemBioPharm U1212 INSERM – UMR 5320 CNRS, Bordeaux University, France
Supply, pharmaceutical grading and biopharmaceutical consideration of amyloglucosidase (AMG) solution in congenital sucrase-isomaltase deficiency (CSID) treatment R. Lambert1, A. Lachaux3, A. Louguet1, C. Dupuis1, B. Lapras1, C. Paillet2, C. Pivot2, S. Filali1, C. Merienne1, F. Pirot1
1 Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon
2 Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon
3 Service de gastroentérologie, hépatologie et nutrition pédiatrique, Hôpital Femme Mère Enfant - Hospices Civils de Lyon et Université Claude Bernard Lyon 1, Lyon, France
Setting up a fun training course on the preparation of anticancer drugs within a Regional Hospital Group Aurélie Etangsale1, Laetitia Albertini2, Maud Bascoulergue1, Francis Fauvelle2 Bernadette Coret-Houbart1
1 Pharmacy service, Robert Ballanger Hospital Center, 93602 Aulnay-sous-Bois, FRANCE
2 Pharmacy service, Le Raincy-Montfermeil Hospital Center, 93370 Montfermeil, FRANCE
Physicochemical and biopharmaceutical approach to a topical formulation of dabrafenib for the local treatment of langerhansian histiocytosis E. Fischer1, K. Tardivel1, M. Mazuel1, A. Louguet1, A. Dubromel3, C. Theillac4, S. Dalle4, N. Vantard5, C. Paillet2, C. Pivot2, B. Lapras1, C. Merienne1, S.Filali1, F. Pirot1
1 Hospices Civils de Lyon - Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot
2 Hospices Civils de Lyon - Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot
3 Hospices Civils de Lyon - Pharmacie et Stérilisations Centrales, Centre de Documentation et d’Information Pharmaceutiques
4 Hospices Civils de Lyon - Centre Hospitalier Lyon Sud, Service de dermatologie
5 Hospices Civils de Lyon - Centre Hospitalier Lyon Sud, Unité de Pharmacie Clinique Oncologique
Magistral preparation of fumagillin for the treatment of Enterocytozoon bieneusi microsporidiosis: between active pharmaceutical ingredient shortage and major therapeutic need. S. Filali1, C. Dupuis1, A. Louguet1, M. Rabodonirina2, N. Laverdure3, Ph. Poirier4, A. Von Kanel1, B. Lapras1, C. Pivot1, C. Paillet1, C. Merienne1, F. Pirot1
1 Preparation and Control of Medicines Unit, FRIPHARM platform, Pharmacy, Edouard Herriot Hospital - Hospices Civils de Lyon.
2 Parasitology and Medical Mycology Department, Croix-Rousse Hospital - Hospices Civils de Lyon.
3 Pediatric gastroenterology, hepatology and nutrition department, Femme Mère Enfant Hospital - Hospices Civils de Lyon.
4 Parasitology and mycology department, Clermont-Ferrand University Hospital - Gabriel Montpied Hospital.
Antimicrobial preservation efficacy of glucose and maltitol syrups with and without preservatives for paediatric formulations Thomas CARPENTIER, Eve MAILLARD, Mathilde ROYER, Lina MUSTAPHA, Frédéric MARÇON
Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France
Optimization of the preparation and control of melatonin capsules M. Stoops1, R. Mazet1, M Durand1, M-D. Desruet1,2, P. Bedouch1,3
1. Department of Pharmacy, Grenoble Alpes University Hospital, France
2. Radiopharmacy Bioclinic Laboratory, Grenoble Alpes University, France
3. ThEMAS, TIMC-IMAG UMR CNRS 5525, Grenoble Alpes University, France
Development of a camera-assisted educational tool for the training and evaluation of operators in a cytotoxic production unit. Herlin.A1 ; Claraz.P1; Meghnagi.R1; Bourdon.O1; Storme.T1
1 Pharmacy department, Hôpital Robert Debré, 48 boulevard Sérurier 75019 Paris Implementation of DOTATOC-Gallium 68 (68Ga) radiolabelling Montanard E.1, Lopez S. 1, Carpenet-Guery H.1
1 Department of Nuclear Medecine - Dupuytren Hospital, 2 Avenue Martin Luther King, 87000 Limoges - France
Dr P. Rohrbach, CH Verdun Comparative study of the different Closed System Transfer Devices available in France for the preparation of injectable immunotherapies. Albaut V.1, Brobst M.1, Colliat F.2, Castel D.1
1 Pharmacie, Centre Hospitalier Alès Cévennes, Alès, France
2 Pharmacie, Hôpitaux du bassin Thau, Sète, France
Sterilization of infusion bags : is removing the secondary packaging safe? AF Dumas1, R Pechaud1, M Rannou1, I Dufrene1, H Hida1
1 Service Pharmacie, Centre Hospitalier de Valence
The Errors Tray: a simulation tool for evaluating professional practices in a chemotherapy production unit Tristan Rubin1, Clément Cappelier1, Florine Chollet1, Sonia Mitreski1, Victor Massot1, Chloé Plichon1, Virginie Andre1, Xavier Pourrat2
1 Oncological Clinical Biopharmacy Unit, CHRU Tours, France
2 Trousseau Pharmacy, CHRU Tours, France
Validation of a new medical device devoted for autologous serum eye drops sterile preparation J. Heloury1, B. Dessane1,2, O. Vergnaud1, A. Venet1, V. Servant1, S. Crauste-Manciet1,2
1 Pharmaceutical Technology Department, Bordeaux University Hospital, France
2 ARNA ChemBioPharm U1212 INSERM – UMR 5320 CNRS, Bordeaux University, France
Supply, pharmaceutical grading and biopharmaceutical consideration of amyloglucosidase (AMG) solution in congenital sucrase-isomaltase deficiency (CSID) treatment R. Lambert1, A. Lachaux3, A. Louguet1, C. Dupuis1, B. Lapras1, C. Paillet2, C. Pivot2, S. Filali1, C. Merienne1, F. Pirot1
1 Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon
2 Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon
3 Service de gastroentérologie, hépatologie et nutrition pédiatrique, Hôpital Femme Mère Enfant - Hospices Civils de Lyon et Université Claude Bernard Lyon 1, Lyon, France
Setting up a fun training course on the preparation of anticancer drugs within a Regional Hospital Group Aurélie Etangsale1, Laetitia Albertini2, Maud Bascoulergue1, Francis Fauvelle2 Bernadette Coret-Houbart1
1 Pharmacy service, Robert Ballanger Hospital Center, 93602 Aulnay-sous-Bois, FRANCE
2 Pharmacy service, Le Raincy-Montfermeil Hospital Center, 93370 Montfermeil, FRANCE
Physicochemical and biopharmaceutical approach to a topical formulation of dabrafenib for the local treatment of langerhansian histiocytosis E. Fischer1, K. Tardivel1, M. Mazuel1, A. Louguet1, A. Dubromel3, C. Theillac4, S. Dalle4, N. Vantard5, C. Paillet2, C. Pivot2, B. Lapras1, C. Merienne1, S.Filali1, F. Pirot1
1 Hospices Civils de Lyon - Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot
2 Hospices Civils de Lyon - Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot
3 Hospices Civils de Lyon - Pharmacie et Stérilisations Centrales, Centre de Documentation et d’Information Pharmaceutiques
4 Hospices Civils de Lyon - Centre Hospitalier Lyon Sud, Service de dermatologie
5 Hospices Civils de Lyon - Centre Hospitalier Lyon Sud, Unité de Pharmacie Clinique Oncologique
Magistral preparation of fumagillin for the treatment of Enterocytozoon bieneusi microsporidiosis: between active pharmaceutical ingredient shortage and major therapeutic need. S. Filali1, C. Dupuis1, A. Louguet1, M. Rabodonirina2, N. Laverdure3, Ph. Poirier4, A. Von Kanel1, B. Lapras1, C. Pivot1, C. Paillet1, C. Merienne1, F. Pirot1
1 Preparation and Control of Medicines Unit, FRIPHARM platform, Pharmacy, Edouard Herriot Hospital - Hospices Civils de Lyon.
2 Parasitology and Medical Mycology Department, Croix-Rousse Hospital - Hospices Civils de Lyon.
3 Pediatric gastroenterology, hepatology and nutrition department, Femme Mère Enfant Hospital - Hospices Civils de Lyon.
4 Parasitology and mycology department, Clermont-Ferrand University Hospital - Gabriel Montpied Hospital.
Antimicrobial preservation efficacy of glucose and maltitol syrups with and without preservatives for paediatric formulations Thomas CARPENTIER, Eve MAILLARD, Mathilde ROYER, Lina MUSTAPHA, Frédéric MARÇON
Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France
Optimization of the preparation and control of melatonin capsules M. Stoops1, R. Mazet1, M Durand1, M-D. Desruet1,2, P. Bedouch1,3
1. Department of Pharmacy, Grenoble Alpes University Hospital, France
2. Radiopharmacy Bioclinic Laboratory, Grenoble Alpes University, France
3. ThEMAS, TIMC-IMAG UMR CNRS 5525, Grenoble Alpes University, France
Development of a camera-assisted educational tool for the training and evaluation of operators in a cytotoxic production unit. Herlin.A1 ; Claraz.P1; Meghnagi.R1; Bourdon.O1; Storme.T1
1 Pharmacy department, Hôpital Robert Debré, 48 boulevard Sérurier 75019 Paris Implementation of DOTATOC-Gallium 68 (68Ga) radiolabelling Montanard E.1, Lopez S. 1, Carpenet-Guery H.1
1 Department of Nuclear Medecine - Dupuytren Hospital, 2 Avenue Martin Luther King, 87000 Limoges - France
