2012 Conference

October 3-5 - La Grande Motte - France

Preparations : past and future

Selection criteria of injectables prepared in the hospital Pascal Bonnabry Pharmacy, Geneva University Hospitals (HUG),
Section of pharmaceutical sciences, University of Geneva, University of Lausanne,
Geneva, Switzerland Specials in the UK – A model for Europe ? J.C. Smith All Wales Quality Assurance Pharmacist,
St Mary’s Pharmaceutical Unit Cardiff & Vale
Cardiff & Vale University Health Board, Cardiff, UK Taylor-made preparations by pharmaceutical industry B. Horrocks Director of QA for Compounding in EU
Baxter – UK

Reviews on chemical contamination risks

Chemical contamination with cytotoxics: sources of contaminations (vials & final products) S. Crauste-Manciet Paris Descartes University; Faculty of Pharmacy; INSERM U1022; CNRS UMR8151;
Chimie ParisTech; Sorbonne Paris Cité; Chemical, Genetic and Imaging Pharmacology Laboratory, F-75006 Paris, France
CHI Poissy Saint Germain-en-Laye, Pharmacy department, 20 rue Armagis. 78105 Saint Germain-en-Laye, France Surface contamination in hospitals P. JM. Sessink Exposure Control Sweden AB Biological Monitoring R. Schierl Institute for Occupational, Social and Environmental Medicine,
Munich University, Munich, Germany
(Director Prof. D. Nowak, M.D.) The Experience in Quebec: Four Years after the Publication of a Prevention Guide Jean-François Bussières, Delphine Merger, Cynthia Tanguay Sainte-Justine UHC, University of MontrealCanada

Future for facilities and controlled areas

Hydrogen peroxide vapour (HPV) decontamination technology with Bioquell’s patented ‘dual loop’ system for small (isolators, chambers) and large volumes (cleanrooms) Alain Pineau Bioquell SAS Physical data of the DPTE® system with assurance of microbial quality D. Meyer GETINGE
Importance of ergonomics in the design of the isolators for the hospital sterile preparations S. Carpmail EXTRACT TECHNOLOGY
MultiWay System®, the Solution Offering optimal Conditions for the Secure Transfer and Removal of Toxic & Potentially Infectious and Related Medical waste E. Gohier JCE BIOTECHNOLOGY How technologies and transfers can support chemotherapies preparation units C. Lambert Lourd’Innov SAS (France)

Short oral scientific communications

Audit of the practices of handling anticancer agents F. Moissette¹, A.C. Gairard-Dory¹, K. Fonmartin¹, F. Hassanieh¹, S. Ndaw², B. Gourieux¹ 1. Hôpitaux Universitaires de Strasbourg, France,
2.Institut National de Recherche et de Sécurité, France Hospital risk management: Application of FMECA method (failure modes, effects and criticality analysis) on cancer chemotherapy process Amélie HUGON, Fabienne POIROT-LUTRIN, Marie Line MOTTIER, Philippe LOURMAN Ghislaine DERVIEUX, Jacqueline BERLIOZ Service Pharmacie, Centre Hospitalier de la Région d’Annecy
1 avenue de l’hôpital METZ-TESSY BP 90074
74374 PRINGY CEDEX Risk management strategy of Cytotoxic drugs and monoclonal antibodies therapy preparation M. Ponseele¹, N. Nicolas¹, C. Clémence¹, M. Mougeot² 1 Pharmacie Hôpital Bel Isle - HPM, Metz
2 Service Qualité et Gestion des Risques - HPM, Metz Chemical contamination control in the step of routing cancer preparations Laetitia Minh Mai Lê¹, Sophie He¹, Hassane Sadou-Yayé², Romain Desmaris², Patrice Prognon¹, Eric Caudron¹ 1 Hôpital Européen Georges Pompidou (AP-HP), Service de Pharmacie, Paris, France
2 Institut Gustave Roussy, Service de Pharmacie, Villejuif, France Chemical decontamination validation of an isolator using for cytotoxic drugs preparation in view of activity transfer to sterile non cytotoxic drugs preparation LMM Lê^2,3, E Caudron^2,3, D Pradeau⁴ , Y Bézie¹, M Jardin¹ 1 Groupe Hospitalier Paris Saint Joseph, Pharmacy Department, Paris, France
2 Georges Pompidou European hospital (AP-HP), Pharmacy Department, Paris, France
3 Université Paris-Sud, Analytical Chemistry Laboratory EA 4041, Châtenay-Malabry, France
4 General Agency of Health Products and Equipment (AP-HP), Laboratory of Analytical Development, Paris, France Drug preparation with CytoCare: monitoring product contamination, environmental contamination and exposure of pharmacy technicians P. Sessink¹, G. Leclercq², D. Wouters² 1 Exposure Control Sweden AB
2 Cliniques Universitaires Saint-Luc Brussels Improvement of the security of batch-preparation of anticancer drugs : implementation of authorities queries P. Bardo, M. Gauthier, L. Bisseux, D. Sankhare, L. Benassaia, C. Roux, V. Breteau, P. Faure, I. Madelaine, N. Jourdan Pharmacie, Hôpital Saint-Louis, AP-HP, Paris Stability of etoposide solutions in disposable infusion devices type Intermate® Alison Klasen^{1, 3}, Romain Kessari², Lionel Mercier^{2, 3}, Cyril Valade², Romain Desmaris², Angelo Paci^{2, 3} 1 Département de Biologie et Pathologie médicales. IGR, 114, rue Edouard Vaillant - 94805
VILLEJUIF Cedex, France.
2 Département de Pharmacie Clinique. IGR, 114, rue Edouard Vaillant - 94805 VILLEJUIF Cedex, France.
3 Service Interdépartemental de Pharmacologie et d’Analyse du Médicament. IGR, 114, rue Edouard Vaillant - 94805 VILLEJUIF Cedex, France. Long term microbial stability study for implementation of batch production for cytotoxic drugs in hospital pharmacy. A. Matheron, M. Cheron, R. Vazquez, M.N. Guerrault-Moro, D. Brossard, S. Crauste-Manciet CHI Poissy - St Germain en Laye
20 rue Armagis, 78105 St Germain en Laye – France. Physical assessment of the integrity of the overwrapping as a part of the validation of operators for long term microbiological stability of sterile preparations A. Matheron, R. Duro, R. Vazquez, M.N. Guerrault-Moro, D. Brossard, S. Crauste-Manciet Centre Hospitalier Poissy - St Germain en Laye
20 rue Armagis, 78105 St Germain en Laye - France. Stability study of fortified antibiotic eye drops with a spectrophotometric dosage Mélanie Gérard, Chloé Dubroca, Jérémy Lecardeux, Marie Poirier, Arnaud Venetr, Audrey Jourand, Jean Grellet Unité de préparation stérile pharmacie,
CHU de Bordeaux Pellegrin,
place amélie Raba Léon,
33076 Bordeaux Cedex, France. Stability of a 5 mg/ml imipenem-cilastatin eyes drop Mathilde Grande, Sophie Potin, Marie-Laure Brandely, Laurence Labat, Rui Batista, François Chast Service de pharmacie
Hôpitaux Universitaires Paris Centre, AP-HP,
1 place du Parvis Notre-Dame, 75004 Paris Improving quality of care and patients safety: Ready for use doses of drugs prepared by the pharmacy M. Sassier¹, M. Morisse ¹, L. Ait Bouchrim ², V. Chédru-Legros ¹ 1 Pharmacist, University hospital, 14000 Caen
2 Internal pharmacist, University hospital, 14000 Caen Establishment of an anticipated chemotherapy preparations system in gastrointestinal oncology unit P. Pavie, M. Adam-Fontaine, M. Lottin, A. Leroux, A. Coquard, B. Dieu Pharmacie du centre hospitalier universitaire de Rouen
1 rue de Germont
76000 Rouen France Feasibility of cytotoxic preparation in advance at the hospital center of Le Mans Mathieu Léger, Lobna Jemour, Hélène Perrier, Anne-Marie Vidal, Anne-Marie Caminondo, Catherine Naveau-Ploux Centre Hospitalier Le Mans,
France. Impact of the anticipated preparations on the organisation of the daily activity in a team preparing anti-cancer drugs E. Yali, S. Violette, C. Caty-Villa, G. Herbin, G. Brunet, E. Kiep, C. Pobel Pharmacie, Centre Hospitalier de Saintonge,
17100 Saintes, France Preparation of 5 FU infusers: from anarchy to dose banding Stéphanie Martignoni^{1, 2}, Dr. Grégory Podilsky¹, Dr. Béatrice Gay³, Prof. André Pannatier^1,2 1 Service de Pharmacie CHUV Lausanne, Suisse,
2 Ecole Pharmacie Genève-Lausanne, Université de Genève
3 Centre Coordonné d’Oncologie CHUV Lausanne, Suisse Evaluation of stock solution manufacturing process campaign of 5-Fluorouracil broadcaster J. Fouque, G. Belhabib, B. Verrière, H. Aboudagga, P. Prognon, L. Havard Service Pharmacie Hôpital Européen Georges Pompidou,
France. 20 rue Leblanc
75908 PARIS Cedex 15 Permeability assessment of hydrogen peroxide through home elastomeric infusion pump devices after gas sterilisation in isolator D. Reitter, R. Duro, R. Vazquez, M.N Guerrault-Moro, D. Brossard, S. Crauste-Manciet Centre Hospitalier Poissy - St Germain en Laye
20 rue Armagis
78105 St Germain en Laye – France Subcontracting the manufacture of chemotherapies for a distant hospital Cédric Blatrie, Christian Schaeli Pharmacie des Hôpitaux de l’Est Lémanique
Vevey, Suisse A regional harmonization of chemotherapy, antiemetic and hydration protocols P. Savary¹, J. Delage¹, M. Adam², B. Chéru³, L. Bastit³, M. Daouphars³, J. Doucet¹, E. Rémy¹ 1 OMéDIT Haute-Normandie, CHU de Rouen, 1 rue de Germont, 76031 ROUEN CEDEX, FRANCE
2 Pôle Pharmacie, CHU de Rouen, 1 rue de Germont, 76031 ROUEN CEDEX, FRANCE
3 Réseau Onco-Normand, 2 avenue de la liberté, 76300 SOTTEVILLE-LES-ROUEN, FRANCE Operators training and qualification in french and swiss healthcare establishments: where are we? P. Pavie, G. Podilsky, J-C. Devaud, A.Pannatier Pharmacie du centre hospitalier universitaire Vaudois (CHUV),
Rue de Bugnon 46, 1011 Lausanne
Assessment and validation of the operators working in cytotoxics preparation unit M. Fourtage, V. Graff, F. Couturier Pharmacie, Clinique Ste Anne,
Strasbourg, France
Experience feedback on the use of portable detectors of peroxide of hydrogen (H₂O₂) in a unit of preparation centralized of cytotoxics M. Pinturaud, C. Legros, M. Vasseur, R. Baccouch, B. Décaudin, P. Odou Institut de pharmacie du Centre Hospitalier Régional et Universitaire de Lille, Lille (France) Operational qualification of the automat DIANA under laminar flow hood in hospital pharmacy Gwenaelle MATON¹, Elodie SIMON¹, Hélène BEAUSSART¹, Damien LANNOY^1,2, Pr Pascal ODOU^1,2 1- Préparatoire, Institut de Pharmacie - CHRU LILLE, France
2- Laboratoire de Biopharmacie, Pharmacie Galénique et Hospitalière, EA 4481 GRIIOT, Faculté des Sciences
Pharmaceutiques et Biologiques, LILLE, France. Analysis and management of non-conformities in a quality laboratory for chemotherapeutics control Sophie He¹, Laetitia Minh Mai Lê^{1, 2}, Laurent Havard¹, Patrice Prognon^{1, 2}, Eric Caudron^{1, 2} 1 Hôpital Européen Georges Pompidou, AP-HP, Paris, France
2 Université Paris-Sud EA4041, Châtenay-Malabry, France Interest of non-conformities ands complaints follow-up un a centralised intraveinous additive service C. Georgel, C. Dumont, D. Noel, D. Dautel, P. Coupé Centralised Intraveinous Additive Service, Pharmacy,
Jean Bernard Hospital,
59300 Valenciennes, France Video-recognition of Erbitux®, Cisplatine and Navelbine® vials: Validation of the vial identification process under real conditions of use B. Dalifard, M. Dermu, B. Le Franc, E. Griesemann, J-P. Cante Groupe Hospitalier La Rochelle Ré Aunis

Workshops

Photos

In plenary session Workshops The relaxation area