2023 Conference
26th European GERPAC Conference
October 4, 5 & 6, 2023 - Hyères - France
In this space, you will find all the congress communications including conferences, round table, short oral communications and poster presentations.
Opening of the conference
Concurrent workshops
How to write and publish scientific work?
F. Lagarce (Angers - France)F. Marçon (Amiens - France)
Creating a Compounding Unit
I. Roland (Liège - Belgium)MN Guerrault (Paris - France)
L. Escalup (Paris - France)
Outsourcing of chemotherapy preparations: practical exercises
ML Brandely-Piat (Paris - France)JM Canonge (Toulouse - France)
Automation of production in hospital pharmacy
I. Kramer (Mainz - Germany)S. Crauste-Manciet (Angers - France)
F. Sadeghipour (Lausanne - Switzerland)
Analytical method validation for the quality control and stability study of hospital preparations: why and how ?
P Chennell (Clermont-Ferrand - France)E D’Huart (Nancy - France)
C Merienne (Lyon - France)
Printing 3D of drugs
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Access is restricted to GERPAC members and to those registered for the distance learning format of this 2023 edition.
Moderators
I Soulairol (Nîmes - France) - S Crauste-Manciet (Angers - France)
State of the art 3D printring of drugs
I Soulairol (Nîmes - France)
Implementation of 3D printing in a cancer centre.
M. Annereau, L. Denis, A. Dowek, A. Rieutord - Villejuif (France)
Bioequivalence of 3D-printed tablets produced at the point-of-care
I Lafeber (Leiden -The Netherland)
3D printing in pediatrics: feed back from Nîmes University Hospital
I Soulairol (Nîmes - France)
Innovation - Research
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Access is restricted to GERPAC members and to those registered for the distance learning format of this 2023 edition.
Moderators
D. Brossard (Paris - France) - F Marçon (Amiens - France)
Pylote technology: innovation to control the risk of microbial contamination from preparation to use of finished products
M Guittard (Dremil-Lafage)
Extracellular vesicles as non viral drug carriers
J. Dancourt 1, B. Sheryl 1, E. Piovesana 2, G.Lavieu 11. Université Paris Cité, INSERM U1316, UMR 7057/CNRS, Paris, France
2. Current address: Laboratory for Aging Disorders, Laboratory for Translational Research, EOC Bellinzona (Bios+), Switzerland.
Presentation of works & publications
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Open access validation tool for dosage methods: ValidR
F Marçon (Amiens - France)
Training objectives for personnel involved in capsule preparation
F Marçon on behalf of the “Groupe formulation du GERPAC” (Amiens, France)
Practical Pharmaceutics 2nd edition "An international guideline for the preparation, care and use of medicinal products"
P Le Brun (Leiden -The Netherland)
EU Guidance for safe management of hazardous medicinal products at work.
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Access is restricted to GERPAC members and to those registered for the distance learning format of this 2023 edition.
EU Guidance for safe management of hazardous medicinal products at work.
P Sessink (Exposure Control Sweden)
Critical situations: business continuity planning
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Moderators
F Sadeghipour (Lausanne - Switzerland) - D Lannoy (Lille - France)
Activity continuity plan for Aseptic preparations
F Sadeghipour (Lausanne)
Simulation tool to prepare cyber attack in oncology preparation unit
ML Brandely-Piat (Paris - France)
Environnemental controls of controlled areas and risk management
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Access is restricted to GERPAC members and to those registered for the distance learning format of this 2022 edition.
Moderators
S Crauste-Manciet (Angers - France) - P Chennell (Clermont - Ferrand - France)
French Good Compounding Practices (BPP): Environnemental monitoring of cleanrooms in hospital pharmacies
T Storme (Paris - France)
Contamination Control Strategy – what use for improved control and benchmarking of hospital compounding?
J Hargreaves (Pontrieux - France)
Hot topics
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Access is restricted to GERPAC members and to those registered for the distance learning format of this 2023 edition.
Moderators
S Crauste-Manciet (Angers - France)- P Chennell (Clermont - Ferrand - France)
Design of an innovative laboratory dedicated to the analysis of conventional anticancer agents : CytoxLab
S Fleury Souverain, V. Vallet, P. Bonnabry (Genève - Switzerland)
Publication from French National Agency for health and medico social performance (ANAP):
W Baudras - H Eychenié
Collaborative design of a self-assessment tool for the advanced therapy medicinal product circuit
W Baudras - ANAP
Robotic compounding system for sterile preparations
H Eychenié - ANAP
Pharmaceutical Technology Master course’s award
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Access is restricted to GERPAC members and to those registered for the distance learning format of this 2023 edition.
Monitoring of squalenoyl gemcitabine nanomedicines in single living breast cancer cells by Raman imaging
B Fulbert1, A Al Assaad1, D Desmaele2, E Fossier1, L Van Gulick 1, F Slimano1, S Dukic1, S Mura2, H Morjani1, A Beljebbar11 – Université de Reims Champagne Ardenne, BioSpecT EA 7506, UFR de Pharmacie, 51096 Reims, France
2 – Université Paris-Saclay, UMR CNRS8612, Institut Galien Paris-Saclay, Faculté de sciences pharmaceutiques, Châtenay-Malabry, France
Identification of degradation products and molecular mechanism using experimental and theoritical approchaes: application to oral solution formulation; case of ONC201 in diffuse intrinsic pontine glioma
M Vignes1,2, M Annereau1,2, F X Legrand3, F-V Rioblanc2, R Bodin2, A Rieutord2, L Denis2, P-H Secretan5 and B Do1,41 – Paris-Saclay University, 91400, Orsay, France
2 – Clinical Pharmacy Department, Gustave Roussy Cancer Campus, 114 rue Edouard Vaillant, 94800 Villejuif, France
3 – Paris-Saclay University, CNRS, Institut Galien Paris-Saclay, 91400, Orsay, France
4 – Department of Pharmacy, Henri Mondor Hospital, AP-HP, Créteil, France
5 – Paris-Saclay University, Matériaux et santé, 91400, Orsay, France
Development and characterization of an hydrocortisone based oral dispersible thin film for paediatric treatment
C Boisseillier (AP-HP - Paris - France)
GERPAC award 2023 for the best oral communication
Short oral communications
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Access is restricted to GERPAC members and to those registered for the distance learning format of this 2023 edition.
Moderators
F Lagarce (Angers - France) - L Bouchoud (Genève - Switzerland) - Y Huon (Liège - Belgium)
Public production of therapeutic bacteriophages
B. Lapras1,4,5, C. Kolenda2,4, M. Medina2,4, M. Bonhomme2,4, C. Marchand1,4, C. Merienne1,4, T. Briot3,4, G. Leboucher3,4, F. Laurent2,4, F. Pirot1,4,51 FRIPHARM®, Pharmacie à usage intérieur, Groupement Hospitalier Centre - Hospices Civils de Lyon (HCL), France
2 Laboratoire de bactériologie, Centre national de référence des staphylocoques – HCL, France
3 Pharmacie à usage intérieur, Groupement Hospitalier Nord – HCL, France
4 Consortium PHAG-ONE – PHAGinLyon, France
5 UMR 5305: Laboratoire de Biologie Tissulaire et d’Ingénierie Thérapeutique, Institut de Biologie et Chimie des Protéines, CNRS/Université Claude Bernard Lyon 1, France
Securing the CAR-T-cells (Chimeric Antigenic Receptor – T) supply chain management: Welcome to cognitive aids !
E. Stassaert, R. Desquines, J. Duquesne, N. Gastaut, H. Baaziz, C. Campodonico, S. Ruitort, R. CollompCHU de Nice, Hôpital Archet, 160 Chemin St Antoine de Ginestière, 06200 Nice, France
Impact Analysis of Securing the Chemotherapy Circuit through Computerization and RFID Technology
K. Lefevre, A. Andrieu, A. Lassalle-Diguet, E. RaingeardPharmacotechnie, CHD Vendée, La Roche-sur-Yon, France
DRUGCAM®, a video analysis system: Its impact on risk management in cytotoxic drug production units
A. Andrieu, A. Lassalle-Diguet, E. Raingeard, M. Palamini
Pharmacotechnie, CHD Vendée, La Roche-sur-Yon, France
Secondary packaging of cytotoxics: which elimination process should be adopted?
C. Dréano1, M. Delamotte1, M. Blanchard1, S. Ferec2, E. Touzé1, A. Lebreton11 CHU d’Angers, Pharmacie, 4 rue Larrey, 49933 Angers Cedex 9, France
2 CHU d’Angers, Laboratoire de pharmacologie-toxicologie, 4 rue Larrey, 49933 Angers Cedex 9, France
Man vs machine : how the pharmacist must adapt to improve the robot performance ? The example of subcutaneous (SC) daratumumab
C. Auriault, E. Clapeau, C. Fronteau, M. Bourget, B. Mathat, E. Olivier, N. CormierPharmacie, CHU Nantes, France
Hospital formulation of scopolamine transdermal device for the treatment of agonic rales
E. Gonnard-Déséchaud1, E. Sournac1, L. Usseglio1, C. Marchand1, C. Paillet1, A. Citterio-Quentin2, C. Merienne1, F. Pirot1, 31 Hospices Civils de Lyon (HCL) - Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot
2 HCL - Service de Biochimie et Biologie Moléculaire UM Pharmaco-Toxicologie, Groupement Hospitalier SUD
3 Université Claude Bernard Lyon-1, Faculté de Pharmacie de Lyon, Laboratoire de Biologie tissulaire et Ingénierie Thérapeutique UMR 5305
Potassium sorbate: the ideal pediatric preservative?
S. Jegaden, J. Bordenave, G. BenoitService Pharmacie, Hôpital Armand Trousseau (AP-HP), Paris 75012, France
Impact of manufacturing process on the stability of an anesthetic topical gel
A. Thouvenin1, E. Jaccoulet1, C. De la Reberdière,1 R. Rasamison1, J. Bordenave2, V. Boudy11 Département Recherche et Développement Pharmaceutique, AGEPS, AP-HP, Paris, France
2 Service de Pharmacie, Hôpital Universitaire Armand Trousseau, AP-HP, Paris, France
Quality review of compounded oral solution of spironolactone at 5mg/ml in InOrpha®
R. Desquines, Z. Ramjaun, C. JuradoServices Préparatoire et laboratoire de contrôle. Pôle Pharmacie. Centre Hospitalier Universitaire de Toulouse, France
Risks and prevention associated with handling cytotoxics: setting up and running a continuing professional development training course
A. Delavau, C. Nowak, I. BaudinCentre Hospitalier d’Angoulême, France
Development of a new pediatric formulation of hydrophilic suppositories of pentobarbital and comparison with lipophilic formulations
A. Freisz1, I. Dhifallah3, C. Gaudet1, M. Jouannet1, P. Chennell1,2, E. Beyssac3, G. Garrait3, Y. Bouattour1,2, V. Sautou1,21 CHU Clermont-Ferrand, Pôle Pharmacie, F-63003 Clermont-Ferrand, France
2 Université Clermont Auvergne, CHU Clermont Ferrand, Clermont Auvergne INP, CNRS, ICCF, F-63000 Clermont-Ferrand, France
3 Université Clermont-Auvergne, UFR Pharmacie, MEDIS, Clermont-Ferrand F-63001, France
Radiochemical purity calculation: analysis of the variability of manual integration on result rendering, towards a harmonization of practices
R. Bodin1, C. Smadja1, A. Dowek2, C. Balouzet1, A. Hausser1, C. Hu1, E. Barre3, P. Leclerc4, S. Marie5, V. De Beco6, B. Sabatier11 Service Pharmacie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France
2 Université Paris-Saclay, Lipides : systèmes analytiques et biologiques 91400, Orsay, France
3 Service Pharmacie, Hôpital Saint Louis, AP-HP, Paris, France
4 Service Pharmacie, Hôpital Beaujon, AP-HP, Paris, France
5 Service Pharmacie, Hôpital Kremlin Bicêtre, AP-HP, Paris, France
6 Service Pharmacie, Hôpital Avicenne, AP-HP, Paris, France
Control of parenteral nutrition preparations in ternary mixture : contribution of infrared spectroscopy for the discrimination of three lipid mixtures
M. Berge1, R. Eid2, M. Souce2, E. Guerreiro3, E. Caudron1,2, L. Le1,21 Pharmacy service, Hôpital européen George Pompidou, APHP, Paris, France
2 Lip(Sys)2 analytical chemistry, Pharmacy faculty, University Paris Saclay, Orsay, France
3 Pharmacy service, Hôpital Robert Debré, APHP, Paris, France
Preparation errors detection using gravimetric control on finished product, despite compliant analytical control or in absence of analytical control possibilities
E. Seguin, C. Galon, C. Fernandez, M.-T. Baylatry, A.-C. JolyGroupe Hospitalier AP-HP. Sorbonne Université - Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France
Methods for visual inspection of preparations for parenteral use: between investment, reliability and training in hospital pharmacy
M. Forat1, A. Jambon1, S. Filali2, C. Morel2, C. Merienne1, C. Marchand2, F. Pirot1,2,31 Plateforme Fripharm, Service Pharmaceutique, Groupe Hospitalier Centre Edouard Herriot, Hospices Civils de Lyon, 5, Place d′Arsonval, F-69437 Lyon cedex 03, France
2 Service Biomédical, Groupe Hospitalier Centre Edouard Herriot, Hospices Civils de Lyon, 5, Place d′Arsonval, F-69437 Lyon cedex 03, France
3 Laboratoire de Pharmacie Galénique Industrielle, UMR 5305, ISPB-Faculté de Pharmacie, Université Claude Bernard Lyon 1, 8, avenue Rockefeller, F-69373 Lyon cedex 08, France
Development and validation capillary electrophoresis method for the determination of spironolactone in a new 5 mg/mL oral formulation
M. Sow, R. Vazquez, M.-N. Guerrault-Moro, A.-C. LagravePharmacy, Poissy-St Germain intercommunal hospital, Poissy, France
Evaluation of the surface chemical contamination of gemcitabine bags: ready-to-use versus hospital compounded bags
P. Chennell1, J. Claves2, M. Yessaad2, Y. Bouattour1, V. Sautou11 Université Clermont Auvergne, CHU Clermont Ferrand, Clermont Auvergne INP, CNRS, ICCF, F-63000 Clermont-Ferrand, France
2 CHU Clermont-Ferrand, Pôle Pharmacie, F-63003 Clermont-Ferrand, France
Physicochemical stability of nanoparticle albumin-bound paclitaxel (Pazenir®) infusion dispersion in original glass vials and EVA infusion bags
H. Linxweiler, J. Thiesen, I. KrämerDepartment of Pharmacy, University Medical Centre of Johannes Gutenberg-University, Langenbeckstraße 1, 55131 Mainz, Germany
Microbiological stability study of Atropine 0.01% eye drops in LDPE packaging to produce hospital preparations
L. Rabouam1,3, A. Bousseau2, F. Vallée1,3, J. Delrieu1, M. Chevais1,3, A.-C. Epinette1, M.-L. Ducassou11 Pharmacie à usage intérieur, Centre Hospitalier Universitaire de Poitiers, 2 rue de la Milétrie 86000 Poitiers, France
2 Laboratoire Hygiène CHU Poitiers, France
3 Faculté de médecine et pharmacie de Poitiers, France
Effect of extended -80°C storage on physical integrity of fecal microbiota capsules: a prospective study
C. Stampfli 1, M. Kroemer 1, M. Audry 1, A. Mitouassiwou-Samba 2, F. Aparicio 2, A. Ballif 2, T. Galperine 2,3, B. Guery 2,3, L. Carrez 1, F. Sadeghipour 1,4,51 Service of Pharmacy, Lausanne University Hospital, 1011 Lausanne (Switzerland),
2 Service of Infectious Disease, Fecal Microbiota Transplantation Center, Lausanne University Hospital and University of Lausanne, 1011 Lausanne (Switzerland),
3 French Group of Fecal Microbiota Transplantation (GFTF), Paris (France),
4 Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne (Switzerland)
5 Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva and University of Lausanne (Switzerland)
Overview of the microbiological contamination of eye dropper inserts and caps: influence on the content sterility and the risk of ocular infection
L. Roquefeuil, M. Jobard, T. Dumain, K. Diop-Aka-Ehouman, ML. Brandely-Piat, R. BatistaUnité de Préparations Stériles Ophtalmologiques et Oncologiques, GHU AP-HP Centre-Université de Paris Cité - Site Cochin, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
Ultraviolet C decontamination: analysis of its impact on surface contamination in controlled atmosphere area
P. Auroux, G. Leboucher, T. BriotPharmacie, Groupement Hospitalier Nord - Hospices Civils de Lyon - France
"Escape game" in the Cytotoxic Preparation Unit (UPC): will you manage to dispense chemotherapy bags on time?
J. Moreno, C. Marseloo, M. Cavelier, C. Orsini, R. Varin, A. CoquardPharmacy Department, C.H.U de Rouen, 1 rue de Germont, 76000 Rouen, France
E-Posters - Session A: Dosage - Stability - Microbiology
Sterility testing for lipid mixtures using the BACT/ALERT® system
E. Calimouttoupoulle, M. Dumas, D. Reitter, F. Faibis, N. Boukezia, S. Coulon
Grand Hôpital de l’Est Francilien, site Marne-La-Vallée, France Dosage of calcium (Ca) and magnesium (Mg) by microwave plasma atomic emission spectrometry (MP-AES) in the control of individualized parenteral nutrition (IPN): routine implementation N. Fournier, A. Loison, C. Skorka, F. Verryser
Centre Hospitalier de Valenciennes, France Implementation of a terminal analytical control in cytotoxic reconstitution unit (CRU) J. Gautier, A. Trainaud, C. Collart Dutilleul, P. Le Guevello
Centre Hospitalier Pierre Le Damany, Lannion, France Development and validation of an assay method for Tramadol and Nefopam in solution to study the stability of experimental drugs A. Durand, F. Maillard, V. Delannoy, I. Soulairol
Centre Hospitalier Universitaire de Nîmes, France Assessment of the microbiological impact of an isolator failure on the working environment L. Otte, E. Gava, C. Hanze, C. Gronsfeld, I. Roland
Centre Hospitalier Universitaire de Liège, Belgique Physicochemical stability of sufentanil citrate in RythmicTM administration set reservoirs or in a polyolefin infusion bag diluted in 0.9% sodium chloride or in 5% dextrose at 1 and 10 µg/mL stored at 20-25°C protected from light R. Doncheva, E. D’Huart, J. Vigneron, B. Demore
Centre Hospitalier Universitaire de Nancy, Vandœuvre-lès-Nancy, France Optimization of microbiological sampling in a centralized anticancer drugs preparation unit M. Decuyper, P. Maboudou, S. Tombelle, B. Dectot, F. Danicourt
Centre Hospitalier de Dunkerque, France Stability study of alternative formulation to sirolimus 0.1% cream in a context of raw material breakage A. Gillette, A. Bourges, S. Vrignaud, V. Lebreton
Centre Hospitalier Universitaire d’Angers, France Stability study of Letermovir in solution in 0.9% NaCl polypropylene bags F. Rioblanc, P. Claraz, C. Jadoul, A. Sabri, J. Roupret-Serzec, T. Storme
APHP, Hôpital Robert-Debré, Paris, France Development and validation of a method for the analytical control of letermovir by high performance liquid chromatography coupled with UV-visible (HPLC-UV) within a chemotherapy preparation unit (UPC) S. Villeneuve, C. Baguet, R. Meghnagi, N. Jourdan, F. Le Cheviller, AB. Bouvrain, N. Vaillant, I. Madelaine, M. Brault
APHP, Hôpital Saint-Louis, Paris, France Qualification of an indicative stability method for the detection of impurities in Histidine at a concentration of 117,20 mg / 3mL AP-HP S. Hatim, G. Boccadifuoco, F. Rosa, V. Boudy, S. Dufaÿ
APHP, AGEPS, France Immunotherapies & stability: a costly race against time M. Aouaouche, J. Rose, J. Le Grand, L. Nicolas
APHP, Hôpital Bichat - Claude Bernard, Paris, France
Grand Hôpital de l’Est Francilien, site Marne-La-Vallée, France Dosage of calcium (Ca) and magnesium (Mg) by microwave plasma atomic emission spectrometry (MP-AES) in the control of individualized parenteral nutrition (IPN): routine implementation N. Fournier, A. Loison, C. Skorka, F. Verryser
Centre Hospitalier de Valenciennes, France Implementation of a terminal analytical control in cytotoxic reconstitution unit (CRU) J. Gautier, A. Trainaud, C. Collart Dutilleul, P. Le Guevello
Centre Hospitalier Pierre Le Damany, Lannion, France Development and validation of an assay method for Tramadol and Nefopam in solution to study the stability of experimental drugs A. Durand, F. Maillard, V. Delannoy, I. Soulairol
Centre Hospitalier Universitaire de Nîmes, France Assessment of the microbiological impact of an isolator failure on the working environment L. Otte, E. Gava, C. Hanze, C. Gronsfeld, I. Roland
Centre Hospitalier Universitaire de Liège, Belgique Physicochemical stability of sufentanil citrate in RythmicTM administration set reservoirs or in a polyolefin infusion bag diluted in 0.9% sodium chloride or in 5% dextrose at 1 and 10 µg/mL stored at 20-25°C protected from light R. Doncheva, E. D’Huart, J. Vigneron, B. Demore
Centre Hospitalier Universitaire de Nancy, Vandœuvre-lès-Nancy, France Optimization of microbiological sampling in a centralized anticancer drugs preparation unit M. Decuyper, P. Maboudou, S. Tombelle, B. Dectot, F. Danicourt
Centre Hospitalier de Dunkerque, France Stability study of alternative formulation to sirolimus 0.1% cream in a context of raw material breakage A. Gillette, A. Bourges, S. Vrignaud, V. Lebreton
Centre Hospitalier Universitaire d’Angers, France Stability study of Letermovir in solution in 0.9% NaCl polypropylene bags F. Rioblanc, P. Claraz, C. Jadoul, A. Sabri, J. Roupret-Serzec, T. Storme
APHP, Hôpital Robert-Debré, Paris, France Development and validation of a method for the analytical control of letermovir by high performance liquid chromatography coupled with UV-visible (HPLC-UV) within a chemotherapy preparation unit (UPC) S. Villeneuve, C. Baguet, R. Meghnagi, N. Jourdan, F. Le Cheviller, AB. Bouvrain, N. Vaillant, I. Madelaine, M. Brault
APHP, Hôpital Saint-Louis, Paris, France Qualification of an indicative stability method for the detection of impurities in Histidine at a concentration of 117,20 mg / 3mL AP-HP S. Hatim, G. Boccadifuoco, F. Rosa, V. Boudy, S. Dufaÿ
APHP, AGEPS, France Immunotherapies & stability: a costly race against time M. Aouaouche, J. Rose, J. Le Grand, L. Nicolas
APHP, Hôpital Bichat - Claude Bernard, Paris, France
E-Posters - Session B: Control - Contamination - Practice audit - Training
Control of a pediatric clonidine solution at 10 µg/mL by capillary electrophoresis
L. Trocherie, R. Vasquez, M.-N. Guerrault-Moro, A.-C. Lagrave
Centre Hospitalier Intercommunal Poissy-St Germain, France Preliminary evaluation of the detectability potential of visible particles: comparison between a candling table in accordance with the European Pharmacopoeia and a polarized light table J. Claves, S. Pais, P. Chennell, V. Sautou
Centre Hospitalier Universitaire de Clermont-Ferrand, France Evaluation of the chemical contamination by antineoplastic drugs in a Chemotherapy Reconstitution Unit (URC) in a French hospital M. Masson, J. Heloury, N. Kerneur, E. Peguet, E. Jobard
Hôpital Yves Le Foll, Saint-Brieuc, France Quality control of 5-fluorouracil infusers through packaging M. Nehlil, M. Annereau, T. Busson, A. Rieutord, H. Aboudagga, A. Dowek
Institut Gustave Roussy, Villejuif, France Study of particle contamination in activity areas dedicated to the automated preparation of doses to administer (APDA) I. Bari, E .Gayet, J.-N. Maurer
Centre Hospitalier de Verdun Saint-Mihiel, Verdun, France Residual volume in semi-rigid bags used to prepare anticancer drugs: myth or reality? Evaluation and impact in practice A. Hasoun Najar, L. Josse, S. Martin, G. Leau, O. Gallon
Centre Hospitalier Intercommunal Nord Ardennes, Charleville-Mézières, France Implementation of a training course on risk management for handling cytotoxics in collaboration with a Qualiopi-certified simulation center A. Delavau, E. Bernikier, C. Nowak, L. Danguy Des Déserts, I. Baudin
Centre Hospitalier d’Angoulême, France Parenteral nutrition production: audit of practices targeting the risk of microbiological contamination F. Gaume, A. Ifrah, S. Valy, S. Vrignaud
Centre Hospitalier Universitaire d’Angers, France Feedback from 2 years of reinforced visual control to secure the chemotherapy compunding M. Berge, C. Mequinion, J. Saidi, D. Giraud, J. Touchard, E. Caudron, L. Le
APHP, Hôpital Européen Georges Pompidou, Paris, France Study of the passage of hydrogen peroxide through eye-drops bottles intended for sterility testing during their decontamination in an isolator L. Roquefeuil, M. Jobard, V. Labeau, T. Dumain, M-L. Brandely-Piat, R. Batista
APHP, Hôpital Cochin, Paris, France
Centre Hospitalier Intercommunal Poissy-St Germain, France Preliminary evaluation of the detectability potential of visible particles: comparison between a candling table in accordance with the European Pharmacopoeia and a polarized light table J. Claves, S. Pais, P. Chennell, V. Sautou
Centre Hospitalier Universitaire de Clermont-Ferrand, France Evaluation of the chemical contamination by antineoplastic drugs in a Chemotherapy Reconstitution Unit (URC) in a French hospital M. Masson, J. Heloury, N. Kerneur, E. Peguet, E. Jobard
Hôpital Yves Le Foll, Saint-Brieuc, France Quality control of 5-fluorouracil infusers through packaging M. Nehlil, M. Annereau, T. Busson, A. Rieutord, H. Aboudagga, A. Dowek
Institut Gustave Roussy, Villejuif, France Study of particle contamination in activity areas dedicated to the automated preparation of doses to administer (APDA) I. Bari, E .Gayet, J.-N. Maurer
Centre Hospitalier de Verdun Saint-Mihiel, Verdun, France Residual volume in semi-rigid bags used to prepare anticancer drugs: myth or reality? Evaluation and impact in practice A. Hasoun Najar, L. Josse, S. Martin, G. Leau, O. Gallon
Centre Hospitalier Intercommunal Nord Ardennes, Charleville-Mézières, France Implementation of a training course on risk management for handling cytotoxics in collaboration with a Qualiopi-certified simulation center A. Delavau, E. Bernikier, C. Nowak, L. Danguy Des Déserts, I. Baudin
Centre Hospitalier d’Angoulême, France Parenteral nutrition production: audit of practices targeting the risk of microbiological contamination F. Gaume, A. Ifrah, S. Valy, S. Vrignaud
Centre Hospitalier Universitaire d’Angers, France Feedback from 2 years of reinforced visual control to secure the chemotherapy compunding M. Berge, C. Mequinion, J. Saidi, D. Giraud, J. Touchard, E. Caudron, L. Le
APHP, Hôpital Européen Georges Pompidou, Paris, France Study of the passage of hydrogen peroxide through eye-drops bottles intended for sterility testing during their decontamination in an isolator L. Roquefeuil, M. Jobard, V. Labeau, T. Dumain, M-L. Brandely-Piat, R. Batista
APHP, Hôpital Cochin, Paris, France
E-Posters - Session C: Formulation - Risk management
ChimioPREP®: a too to secure a centralized pharmacy unit for cytotoxic drugs
M. Casper, L. Bourgue, P. Nerrant, S. Rabeuf, M. Ben Reguiga
Centre Hospitalier de Mayotte, France Evaluation of the difficulties associated with the administration of pediatric drugs delivered to outpatient A. Caldas, M. Royer, F. Marçon
Centre Hospitalier Universitaire d’Amiens, France Computer blackout (CBO) in a chemotherapy preparation unit (CT): how to cope? J. Bodet, G. Lafci, M. Abele, A. Villain, I. Sakji, G. Marliot
Centre Oscar Lambret, Lille, France Formulation of an oral suspension of pyrimethamine for pediatric use S. Muhammad, S. Ahil, C. Figueiredo, M. Diakite, P. Marchadour, G. Benoit, J. Bordenave
APHP, Hôpital Armand Trousseau, Paris, France Resumption of the downgraded circuit during a chemotherapy prescription software breakdown from A to Z C. Chabanol, M-L. Ducassou, M. Bay, J. Delrieu
Centre Hospitalier Universitaire de Poitiers, France Administration of DARATUMUMAB by subcutaneous way (SD): what solution to reduce the pain associated with the administration of the drug? C. Hay, J. Villain, I. Dagrenat, M. Boisgontier
Centre Hospitalier de Compiègne Noyon, France
Equipment failure in a Controlled Atmosphere Zone (CAZ) : maintaining sterile drug preparations manufacturing A. Ghorbel, A.-C. Epinette, J. Delrieu
Centre Hospitalier Universitaire de Poitiers, France
Emergency treatment of NRBC victims by needle-free percutaneous administration of antidotes: AGATE Project (Atropine Gun AntidoTE) M. Forat, M. Venet, C. Marchand, J. Bousson, C. Merienne, A. Le-Bagousse, C. Paillet, F. Pirot
Hospices Civils de Lyon, France Optimization and stability study of compounded oral suspension of spironolactone at 5mg/ml for infants R. Desquines, Z. Ramjaun, C. Jurado
Centre Hospitalier Universitaire de Toulouse, France Assessment of exposure to hydrogen peroxide in a parenteral nutrition unit: occupational risks involved? L. Baldachino, D. Remaud, Z. Ribier
APHP, Hôpital Armand Trousseau, Paris, France
Y-site injection compatibility of parenteral medicines with balanced salt solutions Z. Mittmann, J. Thiesen, I. Krämer
University Medical Center, Mainz, Germany Total breakdown in a production unit: how to face the emergency? M. Fontaine, L. Eyquem, B. Laluque
Centre Hospitalier de Bourges, France Pediatric galenic adaptation, when compassionate use is not enough: the case of Clindamycin M. Jacquet, R. Mazet, J. Arata-Bardet, M. Durand, S. Chanoine, M.-D. Brunet, P. Bedouch
Centre Hospitalier Universitaire Grenoble-Alpes, France
Centre Hospitalier de Mayotte, France Evaluation of the difficulties associated with the administration of pediatric drugs delivered to outpatient A. Caldas, M. Royer, F. Marçon
Centre Hospitalier Universitaire d’Amiens, France Computer blackout (CBO) in a chemotherapy preparation unit (CT): how to cope? J. Bodet, G. Lafci, M. Abele, A. Villain, I. Sakji, G. Marliot
Centre Oscar Lambret, Lille, France Formulation of an oral suspension of pyrimethamine for pediatric use S. Muhammad, S. Ahil, C. Figueiredo, M. Diakite, P. Marchadour, G. Benoit, J. Bordenave
APHP, Hôpital Armand Trousseau, Paris, France Resumption of the downgraded circuit during a chemotherapy prescription software breakdown from A to Z C. Chabanol, M-L. Ducassou, M. Bay, J. Delrieu
Centre Hospitalier Universitaire de Poitiers, France Administration of DARATUMUMAB by subcutaneous way (SD): what solution to reduce the pain associated with the administration of the drug? C. Hay, J. Villain, I. Dagrenat, M. Boisgontier
Centre Hospitalier de Compiègne Noyon, France
Equipment failure in a Controlled Atmosphere Zone (CAZ) : maintaining sterile drug preparations manufacturing A. Ghorbel, A.-C. Epinette, J. Delrieu
Centre Hospitalier Universitaire de Poitiers, France
Emergency treatment of NRBC victims by needle-free percutaneous administration of antidotes: AGATE Project (Atropine Gun AntidoTE) M. Forat, M. Venet, C. Marchand, J. Bousson, C. Merienne, A. Le-Bagousse, C. Paillet, F. Pirot
Hospices Civils de Lyon, France Optimization and stability study of compounded oral suspension of spironolactone at 5mg/ml for infants R. Desquines, Z. Ramjaun, C. Jurado
Centre Hospitalier Universitaire de Toulouse, France Assessment of exposure to hydrogen peroxide in a parenteral nutrition unit: occupational risks involved? L. Baldachino, D. Remaud, Z. Ribier
APHP, Hôpital Armand Trousseau, Paris, France
Y-site injection compatibility of parenteral medicines with balanced salt solutions Z. Mittmann, J. Thiesen, I. Krämer
University Medical Center, Mainz, Germany Total breakdown in a production unit: how to face the emergency? M. Fontaine, L. Eyquem, B. Laluque
Centre Hospitalier de Bourges, France Pediatric galenic adaptation, when compassionate use is not enough: the case of Clindamycin M. Jacquet, R. Mazet, J. Arata-Bardet, M. Durand, S. Chanoine, M.-D. Brunet, P. Bedouch
Centre Hospitalier Universitaire Grenoble-Alpes, France
E-Posters - Session D: Production
Standardization of the manufacturing process of excipient aliquots to COVID-19 vaccines
P. Thomann, L. Carrez, A. Pierrot, C. Stampfli, F. Sadeghipour
Centre Hospitalier Universitaire Vaudois, Lausanne, Suisse Emergency preparation of sodium sulfadiazinate injection: case report C. Levaux, C. Meex, S. Servais, I. Roland
Centre Hospitalier Universitaire de Liège, Belgique Preparing eye drops from injectable specialties: using a peristaltic pump, from reconstitution to distribution L. Guiheneuc, M. Bourget, E. Olivier, N. Cormier
Centre Hospitalier Universitaire de Nantes Hôtel-Dieu, Nantes, France Feasibility study and preparation of polyethylene glycol (PEG) syringes for allergological skin tests related to COVID vaccination B. Mathat, M. Bourget, H. El Hanache, E. Olivier, N. Cormier
Centre Hospitalier Universitaire de Nantes Hôtel-Dieu, France Real-Life Test of a Secure Device for the Preparation and Administration of Anticancer Drugs: Chemolock® (ICU Medical) S. Perreau, ML. Brandely-Piat, R. Batista
APHP, Hôpital Cochin, Paris, France Tevadaptor® closed-system novel design: flow separation, homogenization and ergonomic assessments on the new ChemfortTM transfer device E. Cohen, K. Sejean, E. Dang, C. Lepage-Seydoux, B. Bonan
Hôpital Foch, Suresnes, France Musculoskeletal disorders: personnel monitoring and use of Romeo® handling aid M. Mellou, J. Robert, J. Sorrieul, C. Devys
Institut de Cancérologie de l’Ouest site Paul Papin, Angers, France Considering robotic production of injectable anti-cancer drugs? Think ahead! T. Martin, E. Grassi, A. Mitha, H. Aboudagga, C. Bertrand, P. Coliat, COPIL APOTECA FRANCE
Institut de Cancérologie Strasbourg Europe, Strasbourg, Centre Eugène Marquis, Rennes, Gustave Roussy, Villejuif, Communauté Apoteca France Optimization of the sterile compounding preparation process: example of a filling compounder and its qualification M. de Lacroix de Lavalette, A-L. Leroy, P-N. Boivin, M-A. Lester
Centre Hospitalier Universitaire de Rennes, France
The anticipated compounding of injectable anticancer drugs without physician’s prescription: a process study T. Melun, E. Marilly, P. Doucey, S. Kalfon, A. Mace, S. Menguy, F. Forges, X. Simoens
Centre Hospitalier Universitaire de Saint-Etienne, France
Providing a closed-system transfer and administration device for chemoembolisation ensure safe use? A. Bregliano, M. Jugai
Maison de Santé Protestante de Bagatelle, Talence, France Best step to freeze faecal microbiota transplants: native faeces, faecal suspension or pharmaceutical forms ? R. Sintes, G. Navelli, S. Delage, S. Truong, M.-T. Baylatry, C. Fernandez, H. Sokol, A.C. Joly
APHP, Hôpital Saint Antoine, Paris, France Implementation of an anticipated reconstitution circuit, and reconstitutions modalities of cyclophosphamide vials using a PharmashakerV3® T. Neocleous, M. Sangnier, A. Berroneau, G. Bouguéon, J-M. Bernadou
Centre Hospitalier Universitaire de Bordeaux, France Robot assisted compounding users club: the 2025 roadmap A. Mitha, C. Bertrand, P. Coliat, I. Sakli, D. Prebay, S. Cassatella, M. Bastianelli, H. Aboudagga, A. Rieutord
Institut Gustave Roussy Villejuif, Centre Eugène Marquis Rennes, Institut de Cancérologie Strasbourg Europe, Centre Oscar Lambret, Lille, France, Loccioni, Rosora, Italie
Centre Hospitalier Universitaire Vaudois, Lausanne, Suisse Emergency preparation of sodium sulfadiazinate injection: case report C. Levaux, C. Meex, S. Servais, I. Roland
Centre Hospitalier Universitaire de Liège, Belgique Preparing eye drops from injectable specialties: using a peristaltic pump, from reconstitution to distribution L. Guiheneuc, M. Bourget, E. Olivier, N. Cormier
Centre Hospitalier Universitaire de Nantes Hôtel-Dieu, Nantes, France Feasibility study and preparation of polyethylene glycol (PEG) syringes for allergological skin tests related to COVID vaccination B. Mathat, M. Bourget, H. El Hanache, E. Olivier, N. Cormier
Centre Hospitalier Universitaire de Nantes Hôtel-Dieu, France Real-Life Test of a Secure Device for the Preparation and Administration of Anticancer Drugs: Chemolock® (ICU Medical) S. Perreau, ML. Brandely-Piat, R. Batista
APHP, Hôpital Cochin, Paris, France Tevadaptor® closed-system novel design: flow separation, homogenization and ergonomic assessments on the new ChemfortTM transfer device E. Cohen, K. Sejean, E. Dang, C. Lepage-Seydoux, B. Bonan
Hôpital Foch, Suresnes, France Musculoskeletal disorders: personnel monitoring and use of Romeo® handling aid M. Mellou, J. Robert, J. Sorrieul, C. Devys
Institut de Cancérologie de l’Ouest site Paul Papin, Angers, France Considering robotic production of injectable anti-cancer drugs? Think ahead! T. Martin, E. Grassi, A. Mitha, H. Aboudagga, C. Bertrand, P. Coliat, COPIL APOTECA FRANCE
Institut de Cancérologie Strasbourg Europe, Strasbourg, Centre Eugène Marquis, Rennes, Gustave Roussy, Villejuif, Communauté Apoteca France Optimization of the sterile compounding preparation process: example of a filling compounder and its qualification M. de Lacroix de Lavalette, A-L. Leroy, P-N. Boivin, M-A. Lester
Centre Hospitalier Universitaire de Rennes, France
The anticipated compounding of injectable anticancer drugs without physician’s prescription: a process study T. Melun, E. Marilly, P. Doucey, S. Kalfon, A. Mace, S. Menguy, F. Forges, X. Simoens
Centre Hospitalier Universitaire de Saint-Etienne, France
Providing a closed-system transfer and administration device for chemoembolisation ensure safe use? A. Bregliano, M. Jugai
Maison de Santé Protestante de Bagatelle, Talence, France Best step to freeze faecal microbiota transplants: native faeces, faecal suspension or pharmaceutical forms ? R. Sintes, G. Navelli, S. Delage, S. Truong, M.-T. Baylatry, C. Fernandez, H. Sokol, A.C. Joly
APHP, Hôpital Saint Antoine, Paris, France Implementation of an anticipated reconstitution circuit, and reconstitutions modalities of cyclophosphamide vials using a PharmashakerV3® T. Neocleous, M. Sangnier, A. Berroneau, G. Bouguéon, J-M. Bernadou
Centre Hospitalier Universitaire de Bordeaux, France Robot assisted compounding users club: the 2025 roadmap A. Mitha, C. Bertrand, P. Coliat, I. Sakli, D. Prebay, S. Cassatella, M. Bastianelli, H. Aboudagga, A. Rieutord
Institut Gustave Roussy Villejuif, Centre Eugène Marquis Rennes, Institut de Cancérologie Strasbourg Europe, Centre Oscar Lambret, Lille, France, Loccioni, Rosora, Italie
E-Posters - Session E: Production - Organisation - Quality Assurance - Sustainable Development
Isolator Renewal: Don’t forget anything!
C. Jutard, C. Carbasse, E. Coget, M. Rigoni, A. Roche, M.-L. Ducassou, C. Cousin, P. Brouard
Centre Hospitalier Universitaire de Nîmes, France Creation and implementation of a preparation billing tool at Henri Mondor Hospital B. Chapelle, M. Renault-Mahieux, V. Vieillard, M. Paul, M. Carvalh
APHP, Hôpital Henri Mondor, Créteil, France Implementation of an outsourcing activity for radiopharmaceutical preparation B. Treguier, C. Schmitt, C. Provost, M. Steffann, S. Blondeel, J. Fouque, O. Madar
Institut Curie, Saint Cloud, France Ecological and economic impact of a misbelief in a CPU I. Challier, M. Le Goff, N. Bakour, C. Orsini, A. Coquard
Centre Hospitalier Universitaire de Rouen, France Audit of pharmacotechnic pharmacists’s professional practices : from the validation of the prepation to the release of anticancerous drugs preparations P. Carlier, R. Devaux, C. Tan, A. Danckaert, D. De-Bertoult, D. Dautel, H. Huyghe, L. Real
Centre Hospitalier d’Arras, France Change control: Impact analysis for the setting up of chemotherapy banded doses L. Stinat, A. Lassalle-Diguet, A. Andrieu, E. Raingeard
Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France Cytotoxics reconstitution units in the ecological era: Assessment of dematerialization on carbon footprint M. Rigoni, E. Coget, C. Carbasse, A. Roche, M. Ducassou, P. Brouard, C. Cousin
Centre Hospitalier Universitaire de Nîmes, France Utilization of “ready-to-use” (RTU) gemcitabine and irinotecan bags: anticipating change M. Robert, R. Meghnagi, O. Giuly, D. Sankhare, I. Madelaine, N. Jourdan
APHP, Hôpital Saint-Louis, Paris, France Validation of a manufacturing process within a temporary controlled atmosphere area G. Lafci, A. Villain, E. Poutrain, M. Abele, I. Sakji, G. Marliot
Centre Oscar Lambret, Lille, France Synergy of the Lean Management’s approach and computerization: Implementation on manufacturing circuit of individualized parenteral nutrition mixtures N. Gastaut, J. Duquesne, V. Gianella, S. Ruitort, R. Collomp
Centre Hospitalier Universitaire de Nice, France Synergy of the Lean Management’s approach and computerization : Implementation on manufacturing circuit of individualized parenteral nutrition mixtures N. Gastaut, J. Duquesne, V. Gianella, S. Ruitort, R. Collomp
Centre Hospitalier Universitaire de Nice, France Exploration of hypersensitivity to injectable chemotherapies: a 14-year retrospective monocentric study of the impact of this activity in our Centralized Cytotoxic Preparation Unit G. Lafci, A. Lecoutre, J. Courtin, F. Dezoteux, D. Pelletier De Chambure, D. Lannoy, M. Vasseur, P. Odou
Centre Hospitalier Universitaire de Lille, France Qualification of containers for cold storage of cytotoxic vials remains in the isolator of a centralized cytotoxic preparation unit P. Blanc, Y. Balaa, T. Daniel, E. Clou, F. Bordet, M.L. Maestroni
Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France
Centre Hospitalier Universitaire de Nîmes, France Creation and implementation of a preparation billing tool at Henri Mondor Hospital B. Chapelle, M. Renault-Mahieux, V. Vieillard, M. Paul, M. Carvalh
APHP, Hôpital Henri Mondor, Créteil, France Implementation of an outsourcing activity for radiopharmaceutical preparation B. Treguier, C. Schmitt, C. Provost, M. Steffann, S. Blondeel, J. Fouque, O. Madar
Institut Curie, Saint Cloud, France Ecological and economic impact of a misbelief in a CPU I. Challier, M. Le Goff, N. Bakour, C. Orsini, A. Coquard
Centre Hospitalier Universitaire de Rouen, France Audit of pharmacotechnic pharmacists’s professional practices : from the validation of the prepation to the release of anticancerous drugs preparations P. Carlier, R. Devaux, C. Tan, A. Danckaert, D. De-Bertoult, D. Dautel, H. Huyghe, L. Real
Centre Hospitalier d’Arras, France Change control: Impact analysis for the setting up of chemotherapy banded doses L. Stinat, A. Lassalle-Diguet, A. Andrieu, E. Raingeard
Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France Cytotoxics reconstitution units in the ecological era: Assessment of dematerialization on carbon footprint M. Rigoni, E. Coget, C. Carbasse, A. Roche, M. Ducassou, P. Brouard, C. Cousin
Centre Hospitalier Universitaire de Nîmes, France Utilization of “ready-to-use” (RTU) gemcitabine and irinotecan bags: anticipating change M. Robert, R. Meghnagi, O. Giuly, D. Sankhare, I. Madelaine, N. Jourdan
APHP, Hôpital Saint-Louis, Paris, France Validation of a manufacturing process within a temporary controlled atmosphere area G. Lafci, A. Villain, E. Poutrain, M. Abele, I. Sakji, G. Marliot
Centre Oscar Lambret, Lille, France Synergy of the Lean Management’s approach and computerization: Implementation on manufacturing circuit of individualized parenteral nutrition mixtures N. Gastaut, J. Duquesne, V. Gianella, S. Ruitort, R. Collomp
Centre Hospitalier Universitaire de Nice, France Synergy of the Lean Management’s approach and computerization : Implementation on manufacturing circuit of individualized parenteral nutrition mixtures N. Gastaut, J. Duquesne, V. Gianella, S. Ruitort, R. Collomp
Centre Hospitalier Universitaire de Nice, France Exploration of hypersensitivity to injectable chemotherapies: a 14-year retrospective monocentric study of the impact of this activity in our Centralized Cytotoxic Preparation Unit G. Lafci, A. Lecoutre, J. Courtin, F. Dezoteux, D. Pelletier De Chambure, D. Lannoy, M. Vasseur, P. Odou
Centre Hospitalier Universitaire de Lille, France Qualification of containers for cold storage of cytotoxic vials remains in the isolator of a centralized cytotoxic preparation unit P. Blanc, Y. Balaa, T. Daniel, E. Clou, F. Bordet, M.L. Maestroni
Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France
