2019 Conference

22th European GERPAC Conference
October 2, 3 & 4, 2019 - Hyères - France

In this space, you will find all the congress communications including abstracts of presentations, conferences, short oral communications and poster presentations.

Access to all communications requires that you are up to date with your annual GERPAC membership.

Parallel workshops

Round table

Results "microbiological stability” consensus

Contamination: where do we stand?

Hot news from GERPAC

Moderators F. Lagarce, University Hospital Angers
D. Brossard, Paris
MASTERS COMMUNICATIONS BORDEAUX - ANGERS Formulation and stability study of low-dose midazolam capsules for clinical trial P.N. Boivin1, A.C. Bonnaure1, M.A. Lester1
1 Pharmacy department, Rennes University Hospital, Rennes, France
Rapid microbiological sterility test for cytotoxic batch control: is drug complexation effective for restoring microbiological growth? Sangnier Maïté1, Bouguéon Guillaume1,2, Dubois Véronique3,4, Crauste-Manciet Sylvie1,2
(1) Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
(2) ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
(3) Fundamental Microbiology and Pathogenicity Laboratory UMR-CNRS 5234 – University of Bordeaux, France
(4) Microbiology department, Bordeaux university hospital (CHU de Bordeaux), France
MASTERS COMMUNICATION LILLE Stability of frozen 1% voriconazole eye-drops in both glass and innovative containers Marine Roche1,2, MSc, PharmD ; Damien Lannoy1,2, Ph.D., PharmD ; Florence Bourdon1, Ph.D., PharmD ; Cécile Danel2, Ph.D. ; Pierre Labalette3, Ph.D., MD ; Christophe Berneron1, PharmD ; Nicolas Simon1,2, Ph.D. PharmD ; Pascal Odou1,2, Ph.D., PharmD.
1 CHU Lille, Institut de Pharmacie, F-59000 Lille, France
2 Univ. Lille, EA 7365—GRITA—Groupe de Recherche sur les formes Injectables et les Technologies Associées, F-59000 Lille, France
3 CHU Lille, Service d’ophtalmologie, F-5900 Lille, France

Hot Topics 2019

Short oral presentations

Moderators Y. Huon, Liège, Belgium
F. Sadeghipour, University Hospital of Lausanne, Switzerland
F. Lagarce, University Hospital Angers, France
Lean Six-sigma: implementation in pharmaceutical technology unit hospital Sara MOLIGNIER1, Salim SENHAJI1, Voahirana RATSIMBAZAFY3,4, Lucie BOUCHOUD1, Pascal BONNABRY1,2
1 Pharmacie, Hôpitaux Universitaires de Genève, Suisse
2 Section des sciences pharmaceutiques, Université de Genève, Université de Lausanne, Genève, Suisse
3 Pharmacie, Centre Hospitalier Dupuytren, Limoges, France
4 UMR 1094, Université de Limoges, France
Development of a composite score to decide which hospital service should benefit from the patient-specific automatic unit dose distribution system L. Danos1, L. Real1, O. Canon1, I. Patte1 1 Arras’s General Hospital, Boulevard Besnier, 62000 Arras, France The “Radiopharmacy of errors”: a serious game to strengthen quality. T. Martin , S. Espitallier, E. Castelli, M. Rugiero, D. Alberato, C. Maurel, N. Sapin, I. Benard-Thiery
Radiopharmacy department, Centre Antoine Lacassagne, Nice, France
A radiopharmaceutical-based method to investigate container-content interactions Dupire.C 1,2; Crauste-Manciet.S 1,3, Miguel.J 1,2, Bordenave.L 2, Fernandez.P 2,4, Debordeaux.F 1,2, Morgat.C 1,2,4
1 - Pharmaceutical technology department, Bordeaux University Hospital, France
2 - Nuclear medicine department, Bordeaux University Hospital, France
3 - ARNA ChemBioPharm U1212 INSERM - UMR 5320 CNRS, University of Bordeaux, France
4 - INCIA, UMR5287, University of Bordeaux, France
Performance qualification of laminar flow hot-cell for aseptic vial filling during radiopharmaceutical production M. Brault1,2, C. San1,2, N. Vignal1,3, I. Madelaine2, A. Chane-Kene2, E. Barré2, B. Hosten1,2
1 Université de Paris, INSERM UMR-S 1144, Unité Claude Kellershohn, Institut de Recherche Saint-Louis, F-75010 Paris, France.
2 Service Pharmacie, AP-HP, Hôpital Saint-Louis, F-75010 Paris, France.
3 Service de Médecine Nucléaire, AP-HP, Hôpital Lariboisière, F-75010 Paris, France.
Establishment of optimized methodology by GC/MS for hazard evaluation of content-containing interaction during pharmaceutical development TOUSSAINT Balthazar1,2, TOLOSANA Bastien1, LUTON Anaïs1, ROSA Frédéric1, LEGRAND Pauline1,3, BOUDY Vincent1,3, GOULAY-DUFAŸ Sophie1 1 : Département de Recherche et Développement Pharmaceutique, Agence Générale des Equipements et Produits de Santé, 7 rue du Fer à moulin, 75005 Paris, France
2 : Institut Galien Paris-Sud, CNRS, Univ. Paris-Sud, Univ. Paris-Saclay, 92290 Chatenay-Malabry, France
3 : Unité de Technologie Chimique et Biologique pour la santé, UMR8258 Inserm, U1022, Université Paris Descartes, Faculté de Pharmacie, 4 avenue de l’Observatoire, Paris, France
Does the use of a closed system transfer device (DTSC) for administration with elastomeric pumps allow a safe disconnection? E. Peyrilles1, H. Levert1, P. Sessink2, I. Madeleine Chambrin1, N. Jourdan Desrayaud1
1 Pharmacy, Saint-Louis Hospital, AP-HP, France.
2 Exposure Control Sweden AB, Backsippevägen 2, 475 37 Bohus-Björkö, Suède.
Comparative study of healthcare workers exposure to cytotoxic between a French and a Tunisian Hospital K. Zribi1, A. Rajkumar², H. Aboudagga², E. Zribi1, M. Frikha3, F. Safta1, L. Le2,4, E. Caudron2,4
1 Faculté de pharmacie de Monastir – Université de Monastir – Tunisie
2 Service pharmacie – Hôpital Européen Georges Pompidou Paris
3 Service d’oncologie – CHU Habib Bourguiba Sfax – Tunisie
4 Lip(sys)² chimie analytique pharmaceutique – Université Paris Saclay Châtenay-Malabry
Tool development for assessing antineoplastic drugs surface contamination in healthcare services and other workplaces Atgé B1,2,3, Dhersin A1,2, Da Silva Caçao O1,2 Martinez B1, Ducint D1, Verdun-Esquer C2,4, Baldi I2,4, Molimard M1, Villa A5, Canal-Raffin M1,2,4
1 Laboratoire de Pharmacologie Clinique et de Toxicologie, CHU Bordeaux, France
2 INSERM U1219, équipe EPICENE, Université de Bordeaux, France
3 AHI33, Service de Santé au Travail, Bordeaux, France
4 Service de Santé Travail Environnement, CHU de Bordeaux, France
5 Consultation de Pathologie Professionnelle, Hôpital la Timone (AP-HM), Marseille, France
Robotization of antineoplastic drugs preparation: towards a risk reduction for staff of Pharmacotechny Unit. Canal-Raffin M1,2,3, Léger C2, Atgé B4, Mouilleron C1,3, Larrieu C1,3, Da Silva Caçao O1, Molimard M1, Villa A5, Crauste Manciet S6,7, Verdun-Esquer C3,4
1 Laboratoire de Pharmacologie Clinique et de Toxicologie, CHU de Bordeaux, France
2 Service de Santé Travail Environnement, CHU de Bordeaux, France
3 INSERM U1219, équipe EPICENE, Université de Bordeaux, France
4 AHI33, Service de Santé au Travail, Bordeaux, France
5 Consultation de Pathologie Professionnelle, Hôpital la Timone (AP-HM), Marseille, France
6 U1212 Inserm-UMR 5320 CNRS, ARNA Laboratoire ChemBioPharm, Université de Bordeaux, France
7 Département de Pharmacotechnie, CHU Bordeaux, France
Efficiency of 4 solutions in removing 23 conventional antineoplasic drugs from stainless steel surface Nicolas SIMON1,2, Nicolas GUICHARD1, Pascal ODOU2, Bertrand DECAUDIN2, Pascal BONNABRY1, Sandrine FLEURY-SOUVERAIN1
1 Pharmacy, Geneva University Hospitals and School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.
2 Univ. Lille, CHU Lille, EA 7365 – GRITA – Groupe de Recherche sur les Formes Injectables et les Technologies Associées, Lille, France.
Fastidious chemical decontamination after cyclophosphamide vial breaking in a compounding unit O. Petit1, J. Boucher1, M. Vasseur1,2, J. Courtin1, M. Pinturaud1, D. Allorge3, B. Decaudin1,2, N. Simon1,2, P. Odou1,2
1- CHU Lille, Institut de pharmacie, F-59000 Lille, France
2- Univ. Lille, EA 7365 – GRITA – Groupe de Recherches sur les formes Injectables et les Technologies Associées, F-59000 Lille, France
3- CHU Lille, Pôle de Biologie-Pathologie-Génétique, Unité Fonctionnelle de Toxicologie, F-59000 Lille, France
Physical emulsion stability of mixtures of propofol and remifentanil hydrochloride Niklas Nilsson1,2, Katerina Nezvalova-Henriksen1, Ingunn Tho2
1 Oslo Hospital Pharmacy, Oslo, Norway
2 Department of Pharmacy, University of Oslo, P.O.Box 1068 Blindern, 0316 Oslo Norway
Email: Niklas.nilsson@farmasi.uio.no or Niklas.nilsson@sykehusapotekene.no
Vacuum packaging impact on cold-sensitive drugs: example of 5-Fluorouracil A. Cèbe1, G. Bouguéon1,2, M. Sangnier1, A.Khan1, J-M. Bernadou1, P.Dufourcq3, S. Crauste-Manciet1,2
1 Pharmaceutical Technology Department, Bordeaux University Hospital, France
2 ARNA Laboratory ChemBioPharm U1212 INSERM - UMR 5320 CNRS, Bordeaux University, France
3 Biology of Cardiovascular Diseases, Inserm U1034, Pessac, France
Minimising the Risks Associated with the Procurement and Supply of Unlicensed Medicines Dara Murphy, Hannah Miller - Bradford Teaching Hospitals Foundation Trust, Bradford, United Kingdom Exploration of a new tool for antineoplastic agents dosage Antoine Dowek1,2, Laetitia Lê1,3, Tom Rohmer3, Hynd Remita4, Francois-Xavier Legrand5, Marc Lavielle3 et Eric Caudron1,2
1
Service de Pharmacie, Hôpital européen Georges Pompidou, Assistance Publique-Hôpitaux de Pais, 20 rue Leblanc, 75015 Paris
2 Lip(Sys)2 Chimie Analytique Pharmaceutique, UFR de Pharmacie, 5 rue Jean Baptiste Clément, 92290 Châtenay-Malabry, Université Paris-Sud, Université Paris-Saclay
3 Inria Saclay Ile-de-France, CMAP, école polytechnique Route de Saclay 91128 Palaiseau, France
4 Laboratoire de Chimie Physique, CNRS-UMR 8000, Université Paris-Sud, Université Paris-Saclay, Bâtiment 349, 91405 Orsay, France
5 Institut Galien Paris-Sud, Univ. Paris-Sud, CNRS, Université Paris-Saclay, 92290 Châtenay-Malabry, France
Formulation of an oral liquid solution of Carbimazole and validation of a stability indicator assay method. E. Pinet1, C. Roessle1, V. Vasseur1, S. Benakouche1, O. Bourdon1,3,4, T. Storme1,2
1 : Pharmacy Service, Robert Debré Hospital – APHP, Paris, France; 2 : Pharmacology Laboratory Hôpital Robert Debré – APHP, Paris, France; 3 : Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, Paris, France; 4 : Health Education and Practice Laboratory, EA 3412, Paris 13 University, Sorbonne Paris Cité, Bobigny, France
Optimisation of preparation process of 0,2 mg hydrochlorothiazide capsules using a design of experiments S Calland1, Y Bouattour1, L Szkudlara1, M Wasiak1, M Jouannet1, V Sautou1,2
(1) CHU Clermont-Ferrand, Pôle Pharmacie, F-63003 Clermont-Ferrand, France
(2) Université Clermont Auvergne, Institut de Chimie de Clermont- Ferrand. UMR CNRS 6296, F-63000 Clermont-Ferrand, France
Evaluation of a training video support on how to prepare and control a cytotoxic frug during pharmacy resident night-shift Marine Sitbon1, Hail Aboudagga1, Aymeric Chastel1, Laetitia Lê1,2, Eric Caudron1,2
1 : Pharmacy department, Hôpital européen Georges Pompidou (AP-HP), Paris, France
2 : Lip(Sys)2 Pharmaceutical analytical chemistry, UFR de pharmacie, Université Paris Sud, Châtenay-Malabry, France
Pilot Study Assessing the Safety and Ease of Use of a Closed System to Administer Single Agent Infusional Chemotherapy Within an Oncology Day Unit Ann Hogan (Accountable Pharmacist) Lee Merry (Matron Cancer Services) Samantha Brenton (Lead Nurse Cancer
Services) Ruth Allison,(Ward Sister Oncology Day Unit) Torbay and South Devon NHS Foundation Trust

E-posters - Session A

Visual compatibility of Vyxeos® during Y-site administration with selected drugs G. Sicard1, M. Donnette1, N. Martin2, S. Gensollen2, R. Fanciullino1,2 1 SMARTc, CRCM, UMR Inserm 1068, CNRS UMR 7258, Aix Marseille Université U105, Faculté de Pharmacie, Marseille
2 Pharmacie, Hôpital de la Conception, Marseille
Assessment of pharmaceutical control release of chemotherapy preparations using errors simulation program Julien LE CHANJOUR1 ; Aasfa KHAN1; Thomas DELJEHIER1; Aude BERRONEAU1; Sylvie CRAUSTE-MANCIET1,2
(1) Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France.
(2) ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
Optimization of sampling of injectable anticancer drug preparations and improvement of analytical control in a Centralized Preparation Unit Thibaut Gelé,1, Mahamadou Tandia1, Vanessa Thibault1, Laurence Bonhomme-Faivre1, Vincent Castagné1
1 AP-HP, Hôpitaux universitaires Paris-Sud, Hôpital Paul Brousse, Pharmacie à Usage Intérieur, Villejuif, France
Anticancer drug preparations: conformity of volume taken what size syringue? M.Tissot1, A.Bendjama1, AL.Clairet1, M.Mairey1, H.Mockly-Postal1, S.Perrin-Bonnot1, C.Fagnoni-Legat1 et M.Kroemer1
1 : Pôle Pharmacie, CHU Jean Minjoz, 3 bd Fleming, 25030 Besançon
Method Development and validation for assessment of sulfadoxine and pyrimethamine by HPLC-UV E. Marilly, A. Martelin, E. Seidel, D. Salmon, S. Filali, C. Merienne, C. Pivot, F. Pirot.
Service Pharmaceutique – Groupement Hospitalier Edouard Herriot – Hospices Civils de Lyon - France
In-process gravimetric control validation of antineoplasic preparations by the accuracy profile and total error calculation analysis A. Bonavita1, H. Doillet1, C. Jaskowiec1, B. Palas1, S. Poullain1
1 Pharmacie, Centre Hospitalier Intercommunal de Créteil, 40 avenue de Verdun, 94000 Créteil, France
Development and validation of a clomifene citrate quantification method for the stability study of an investigational medical product Agnaoui Samy [1] , Marilly Elisa [1], Marchand Chloé [1], Salmon Damien [1][2], Dhelens Carole [1], Filali Samira [1][2], Merienne Camille [1], Pirot Fabrice [1][2], Pivot Christine [1]
[1] Pharmacie, Hôpital Edouard-Herriot, Lyon, France.
[2] Laboratoire de Pharmacie Galénique Industrielle, ISPB, Lyon, France.
[*] Contact details: name.surname@chu-lyon.fr except for damien.salmon01@chu-lyon.fr
Is syringe sampling performance related to its volume? P. PLANA1, K. LEGER1, M. FONTENEAU1, Y CRETU1, S. PERRIAT1, JM. CANONGE1, F. PUISSET1
1 chemotherapy compounding unit, Oncopôle, UHC Toulouse, France
In-process gravimetric control coupled with vial recognition and dematerialization of chemotherapy production: an option to promote the autonomy of operators and the safety of chemotherapy preparations A. Acramel 1, C. Cros1, FA. Chastang1, J. Fouque2, N. Harlez1, A. Hurgon1, L. Escalup1
1 Departement of Pharmacy, Curie Institute, Paris, France
2 Departement of Radio-pharmacology, Institut Curie, Paris and Saint-Cloud, France
Microwave Plasma Atomic Emission Spectrometry: A New Method for Measuring ions in paediatric parenteral nutrition bags. Wileczek A.1, Egot J.1, Georgel C.1, Bulcourt S.1, Dautel D.1
1 Unité Centralisée de Préparation Stérile, Pharmacie, Centre Hospitalier de Valenciennes (Avenue Desandrouin 59300 Valenciennes)
Parenteral nutrition mixtures controls by inductively coupled plasma optical emission spectrometer: influence of proteins on electrolyte assay S.Vandewoestyne, V.Lebreton, E.Olivier, P.Thomaré
UF Pharmacotechnie, Pharmacie Hôtel Dieu, C.H.U Nantes, Nantes, France.

E-Posters - Session B

Risk analysis of the chemotherapy circuit produced in standard doses N. Cornillet1, R. Vazquez1, M-N. Guerrault1, A-C. Lagrave1
1 Pharmacie, Centre Hospitalier Intercommunal de Poissy/Saint-Germain-en-Laye, 10 rue du champ Gaillard 78300 Poissy
Risk management in parenteral nutrition: risk mapping associated with the preparation process S. Vandewoestyne ; Z. Ramjaun ; M. Tafani
UF Pharmacotechnie, CHU Toulouse, Toulouse, France.
Error simulation in a Centralized Cytotoxic Unit, a playful exercise! Coulpier E., Figueras N., Parrein P., Lheritier E.
Centre Hospitalier de Dieppe, France
Securing extemporaneous oral liquid preparations at CHU Grenoble Alpes C. Ruiz (1), R. Mazet (1-2), J. Leenhardt(1), S. Chanoine(1-2), M-D. Desruet (1), P. Bedouch (1-2)
(1) Département pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, France
(2) Université Grenoble Alpes, Faculté de sciences pharmaceutiques, Grenoble, France
Better manging risks ? Carrying out risk mapping in a pharmacy production unit Manon Etis1, Mathieu Wasiak1, Yassine Bouattour1, Maily Devillers1, Mireille Jouannet1, Valérie Sautou1,2
1 : CHU Clermont-Ferrand, Pôle Pharmacie, F-63003 Clermont-Ferrand, France
2 : Université Clermont Auvergne, Institut de Chimie de Clermont- Ferrand. UMR CNRS 6296, F-63000 Clermont-Ferrand, France
Mistakes benchtop simulation: case in a quality control laboratory Cécile Boughanem, Monique Mikaelian, Mélisande Bernard, Véronique Planas
Quality control departement, PE of AP-HP, AGEPS, France
Risk analysis of the chemotherapy production process: what changes after the deployment of the Drugcam® control tool? V. LAURENT, E. RAINGEARD, A. LASSALLE, L. GALLAY, F.RIAUD, Y. POIRIER
CHD Vendée, Bd Stéphane Moreau, 85925 La Roche sur Yon
Global Risk Analysis applied to outsourcing Sterile Injectable Drugs Julia Rousseau, Kaouther Zribi, Camille Cotteret, Salvatore Cisternino, Joël Schlatter
Service de pharmacie, hôpital Necker-Enfants Malades - 149 rue de Sèvres, 75015 Paris, France
Study of tasks interruptions during the production of chemotherapies Rouault M.1, Sabri A.1, Dumet A.F.1, Gonde H.1, Hervouet C.1, Proux A.sup>2, Doucet J.2, Coquard A.1
1 Pharmacie, CHU de Rouen, Rouen,
2 Médecine Interne Polyvalente, Petit Quevilly
Simulation in pharmaceutical technology education: role of the aseptic filling test in pharmacy technician authorisation VILLAIN.A ; FEUTRY.F; TOULLIC.C; NAVEAU.M; VILLAIN.J; STROBBE.G; SAKJI.I; MARLIOT.G
Pharmacy, Oscar Lambret Center, 59000 Lille
Parenteral nutrition process (from medical prescription to nurse administration) without (re) transcription M. DUMAS, S. COULON, N. CHOUAOU, E. TSHIPATA, J. AUDEMAR, D. REITTER, G. NICOLAOS
Grand Hôpital de l’Est Francilien, France
Use a FMECA (failure modes, effects, and criticality analysis) multidisciplinary on the paediatric parenteral nutrition process M. Royer1, M. Dufosse1, J. Lefebvre1, M. Libessart1, J-M. Dubaele1, E. Vincent2, F. Moreau2, P. Tourneux2, F. Marçon1 1 : Hospital Pharmacy, CHU Amiens, France
2 : Neonatal and Paediatric Intensive Care Unit, CHU Amiens, France

E-Posters - Session C

Qualification of a volumetric automated compounding device to optimize the production of parenteral nutrition bags. Bour F1 & Colom M1, Juliat D1,Cerf P1, Vetele F1, Quessada T1
1 : Pharmacy, East group Hospital, Hospices Civils de Lyon, Bron, France
Which organization to optimize VIDAZA® production ? P. Nizet, A. Lebreton, M. Chappe, L. Le Quay, F. Lagarce
Pharmacy, production unit, CHU d’Angers (France)
Study of Patisiran reconstitution practices: Enforcement of the Summary of Product Characteristics (SPC) in professionals practices P.Laffont1, E. Coget1, E. Floutard1, M-H Sportouch1
1 Pharmacy unit, Beziers hospital center, 2 rue Valentin Haüy, 34525 Béziers, France
Research of the most efficient model for automated dose dispensing (ADD) to be administered in a medicine unitbe P Frery1, E Gayet1, JN Maurer1, JP Collinot1
1 Pharmacie, Centre hospitalier Verdun Saint Mihiel, rue d’Anthouard, 55107 VERDUN cedex
How efficiently can Tilmanocept® syringes be prepared? T. Martin, S. Espitallier, E. Castelli, M. Rugiero, D. Alberato, C. Maurel, N. Sapin, I. Benard-Thiery
Radiopharmacy department, Centre Antoine Lacassagne, Nice
Benefit of operational quality in hospital preparation production performance within a new technical platform Bourtal Imane[1], Martelin Anthony[1], Marilly Elisa[1], Lafont Malo[1], Fulco Baptiste[1], Filali Samira[1][2], Salmon Damien[1][2], Merienne Camille[1], Pivot Christine[1], Pirot Fabrice[1][2]
[1] Pharmacy, Edouard-Herriot Hospital, Lyon, France.
[2] Laboratory of Industrial Galenic Pharmacy, ISPB, Lyon, France.
[*] Coordinates: firstname.lastname@chu-lyon.fr except for damien.salmon01@chu-lyon.fr
Feasibility study for a preparation of ceftazidime 20 mg/mL for intravitreal injection A.Sourisseau1, S.Vandewoestyne1, E.Olivier1, M. Papin1, C.Herrencknecht2, N.Cormier1
1 UF Pharmacotechnie, Pharmacie Hôtel Dieu CHU Nantes, France
2 UFR Sciences Pharmaceutiques et Biologiques Nantes, France
Formulation and Control of a Pediatric Oral Hospital Preparation of 0.1% Ferrous Fumarate Chloé Marchand[1], Elisa Marilly[1], Louise Bossy[1], Anthony Martelin[1], Samira Filali[1] [2], Damien Salmon[1] [2], Camille Merienne[1], Christine Pivot[1] , Fabrice Pirot[1] [2]
[1] Pharmacie, Hôpital Edouard-Herriot, Lyon, France.
[2] Laboratoire de Pharmacie Galénique Industrielle, ISPB, Lyon, France
[*] Coordonnées: prénom.nom@chu-lyon.fr à l’exception de damien.salmon01@chu-lyon.fr
Renovating isolators without activity production interruption, a challenge which generates risks Marine Sitbon1, Laetitia Lê1,2, Hail Aboudagga1, Pascale Ponthou1, Aymeric Chastel1, Nathalie Valin1, Eric Caudron1,2
1 : Pharmacy department, Hôpital européen Georges Pompidou (AP-HP), Paris, France
2 : Lip(Sys)2 Pharmaceutical analytical chemistry, UFR de pharmacie, Université Paris Sud, Châtenay-Malabry, France

E-Posters - Session D

National survey on preparations for outpatients E.Reallon1, M.Wasiak1, P.Chenell1,2, M.Jouannet1, V.Sautou1,2
1 : CHU Clermont-Ferrand, Pôle Pharmacie, F-63003 Clermont-Ferrand, France
2 : Université Clermont Auvergne, Institut de Chimie de Clermont- Ferrand. UMR CNRS 6296, F-63000 Clermont-Ferrand, France
Long-term stability of an infusion containing ketamine, morphine and lorazepam in syringe at 5±3°C M.-L. Colsoul 1,4, J.-D. Hecq2,4, L. Defrene1, N. Goderniaux1,4, , M. Closset1,4, L. Soumoy2,4, B. Bihin3,4, J. Jamart4, L. Galanti1,4 1 Medical Laboratory, CHU UCL Namur, 1 avenue Therasse, 5530 Yvoir, Belgium
2 Department of Pharmacy, CHU UCL Namur, 1 avenue Therasse, 5530 Yvoir, Belgium
3 Scientific Support Unit, CHU UCL Namur, 1 avenue Therasse, 5530 Yvoir, Belgium
4 Drug Stability Research Group, CHU UCL Namur, 1 avenue Therasse, 5530 Yvoir, Belgium
Evaluation of a Safe Infusion Device on reducing occupational exposure of nurses to antineoplastic drugs: a comparative prospective study. Fabien Forges , Bastien Raymond, Marion Hugues, Agnes Macé, Sandrine Menguy, Xavier Simoens.
Institut de Cancérologie Lucien Neuwirth, St Etienne, France.
Microbiological contamination (MC) within the Parenteral Nutrition (PN) isolator : multicentric survey on microbiological control practices. Bopp W.1; Dauriac O.1; Maillan G.1
(1) Pharmacy Unit, University Hospital Center, Limoges, France
Assessment of efficacy of post-infusion tubing rinsing in reducing cytotoxic contamination Pauline Claraz 1, Isabelle Riff 1, Charlotte Vert 1, Isabelle Hennebelle 2, Sophie Perriat 1, Yann Cretu 1, Jean Marie Canonge 1, Florent Puisset 1
1 : pharmacy department, Oncopole Toulouse France.
2 : risk management unit, Oncopole Toulouse France
Stability study of a ternary parenteral nutrition admixture after addition of human insulin Henry H 1,2, Lannoy D 1,2, Simon N 1,2, Bourezg Z 3, Décaudin B 1,2, Odou P 1,2
1. Univ. Lille, EA 7365 - GRITA - Groupe de Recherche sur les formes Injectables et les Technologies Associées, F-59000 Lille, France
2. CHU Lille, Institut de Pharmacie, F-59000 Lille,France
3. Clinical Nutrition, Baxter R&D Europe, Boulevard d’Angleterre 2-4, B-1420 Braine-l’Alleud, Belgique
Chemical stability of amoxicillin in non-electrically driven portable infusion pump ANAPA® Arnaud JORDY, Guillaume BINSON, Pauline LAZARO, Antoine DUPUIS
CHU Poitiers, Pharmacie. 2, rue de la milétrie 86000 POITIERS - FRANCE
Study of the sensitivity of culture media after bio decontamination for use in an isolator B. Palas1, H. Doisneau2, H. Balkhi1, H. Doillet1, C. Jaskowiec1, N. Fauchet2, S. Poullain1
1 Pharmacy Department, Centre Hospitalier Intercommunal de Créteil, France
2 Department of Bacteriology and Hygiene, Centre Hospitalier Intercommunal de Créteil, France
Bacteriophages: sharing pharmaceutical experience around a clinical case A. Ladaique, A. Tible-Sicard, V. Vieillard, P. Desgranges, W. Saeed, M. Paul and M. Verlinde-Carvalho
Hôpital Henri Mondor - Créteil
Antineoplastic drugs surface contamination inside a healthcare service Atgé B1,2,3, Léger C2, Da Silva Caçao O1, Verdun-Esquer C2,4, Molimard M1, Villa A5, Canal-Raffin M1,2,4
1 Laboratoire de Pharmacologie Clinique et de Toxicologie, CHU Bordeaux, France
2 Service de Santé Travail Environnement, CHU de Bordeaux, France
3 AHI33, Service de Santé au Travail, Bordeaux, France
4 INSERM U1219, équipe EPICENE, Université de Bordeaux, France
5 Consultation de pathologie professionnelle, Hôpital la Timone (Aphm), Marseille, France
Did our fabrication process impact on azacitidine stability? A. Khan1, J-M Bernadou1, F. Xuereb1,3, A. Berroneau1, S. Crauste-Manciet1,2 (1) Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
(2) ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
(3) Department of Pharmacokinetics, Groupe PK/PD, INSERM U1034 - Bordeaux University Hospital, France

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