2017 Conference

Conference Opening

Breatout sessions

Theme 1 : Training in hospital pharmaceutical technology, recent trends and future prospects

Theme 2 : Preparation and controls in hospital aseptic units, recent trends and future prospects

Theme 3: Chemical contamination studies, recent trends and future prospects

Theme 4: Stability and interaction studies, recent trends and future prospects

Oral scientific communications

Oral Communications Awards

Short oral communications

Standardization of pediatric parenteral nutrition (PPN): from formulation to implementation M. Sangnier 1, M. Teytaud1, B. Raspaud1, A. Jourand1, S. Crauste-Manciet1,2 1 Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
2 ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
Are there traces of BHT and Antioxidant 425 in hospital compounded drug products ? C. Fauchère1,2, M. Berger1, F. Sadeghipour1,2 1 Lausanne University Hospitals (CHUV), 46 Bugnon Street, 1011 Lausanne, Switzerland
2 School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland
Container-content interactions: ophthalmic drugs and multi dose flasks Y. Le Basle 1, Ph. Chennell2, V. Sautou2 1 CHU Clermont-Ferrand, Pôle Pharmacie, F-63000 Clermont-Ferrand, France
2 Université Clermont Auvergne, CHU Clermont-Ferrand, CNRS, Sigma Clermont, ICCF, F-63000 Clermont-Ferrand, France
Routine detection method for permeation risk assessment of isolator sterilizing agent C. Biasolo 1, B. Dessane1, V. Servant1, S. Crauste-Manciet1,2 1 Pharmaceutical Technology Department - University Hospital of Bordeaux (CHU de Bordeaux)
2 ARNA Laboratory, team ChemBioPharm, U1212 INSERM - UMR 5320 CNRS - Bordeaux University
New sterilizer: preliminary study of hydrogen peroxide (H2O2) diffusion through different medical devices P. Sagourin , C. Humbert, R. Vazquez, M.-N. Guerrault-Moro, A. Durand Pharmacy, Centre Hospitalier Intercommunal de Poissy Saint-Germain, France SimUPAC 360°: the first French digital cytotoxic preparation unit developed in virtual tour for staff training S. Rodier1,2, M. Moine3, F. Beau1, J.C. Nicoulaud3, M. Colombe2,4, V. Noyer5, N. Jourdan3, F. Divanon1, A. Bobay-Madic2,5 1 CLCC François Baclesse, service pharmacie, 14000 Caen, France
2 Association pour le Digital et l’Information en Pharmacie (ADIPh)
3 Hôpital Saint-Louis, APHP, 75010 Paris, France
4 EPSM de Caen, service pharmacie, 14000 Caen, France
5 Centre Hospitalier Robert Bisson, service pharmacie, 14100 Lisieux, France
Improving Quality Management Capacity with Process Mapping G.Tyrrell Clinical Lead Pharmacist Surgery and Aseptic Services, Royal Glamorgan Hospital, UK Implementation of an Automated Production System in Assistance Publique Hopitaux de Marseille Anticancer Drugs Production Units : a feasibility study J. Grimaux , A. Guedon, L. Gauthier Villano, P. Bertault Peres, B. Pourroy Service Pharmacie, CHU TIMONE, 264 rue Saint Pierre, 13 005 Marseille Cedex 5, France
Formulation of a 0.1 mg/mL viscous solution of budesonide for the treatment of eosinophilic esophagitis in children C. Ey , C. Hosselet, B. Villon, J-M. Dubaele, F. Marçon CHU d’Amiens, France Validation of a quick dosage method by UV-Raman spectroscopy for the content control of preparations with complex formulation G. Binson , V. Pigeon, B. Troussier, A. Bremaud, J. Ricou, A. Dupuis Pharmacie - CHU de Poitiers - 2 rue de la milétrie, 86021 Poitiers An Alternative Approach to Transfer, Pre Sterilised Multi Wrapped Products. The Welsh Experience L-J. Keating Quality Control, Pharmacy Department, Royal Gwent Hospital Newport UK Reliability assessment of gravimetric "in process" control of an IV compounding robot Th. Deljehier 1, G. Bouguéon1,2, A. Berroneau1, S. Crauste-Manciet1,2 1 Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
2 ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
Evaluation of the chemical contamination related to the manual cytotoxic production in an isolator and a new robotic drug preparation system (Kiro Oncology®) M. Ayadi , M. Jobard, C. Cros, M-L. Brandely-Piat, R. Batista Service de Pharmacie Clinique, Groupe des Hôpitaux Universitaires Paris Centre, site Hôtel-Dieu, 1 place du Parvis Notre Dame, 75004 Paris, France Impact of process on chemical environmental contamination of a cytotoxic production unit C. Roessle1, T. Chouquet1, A. Acramel1, B. Dectot2, N. Jourdan3, L. Goldwirt1, H. Sauvageon1,2 1 Laboratoire de pharmacologie-biologie, Hôpital Saint-Louis, AP-HP, France
2 Laboratoire de contrôle, Hôpital Saint-Louis, AP-HP, France
3 UPAC, Hôpital Saint-Louis, APHP, France
Evaluation of particulate contamination in an isolator in accordance with the 2016 version of ISO 14644 at the various stages of manufacture of a cancer medication bag P. Hild1, D. Meyer2 1 CH de Roanne
2 DM Compliance
Updated guidelines for the preparation of medical products in healthcare establishment and pharmacy P. Vaconsin, C. Vilain, A. Le, V. Salomon Agence Nationale de Sécurité du Médicament et des produits de santé, 93200 Saint-Denis, France Ready-to-use syringes of melphalan: a race against time A. Feka1,2, L. Berger1, C. Fauchère1,2, G. Podilsky1, F. Sadeghipour1,2 1 Lausanne University Hospital (CHUV), 46 Bugnon Street, 1011 Lausanne, Switzerland
2 School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland
Physical, chemical and microbiological stability study of 0.1 mg.mL-1 atropine eye drops P-O. Farenq , M. Jobard, C. Cros, A. Rahal, C. Bezia, M-L. Brandely-Piat, R. Batista Pharmacy department, GH Hôpitaux Universitaires Paris Centre, site Hôtel-Dieu, 1 place du Parvis Notre Dame, 75004 Paris, France Study of chemical stability and bacteriological contamination of standardized pediatric parenteral nutrition P. Etienne 1, P-A. Faye2,3, S. Molignier1, O. Dauriac1, G. Maillan1 1 Parenteral nutrition department, Pharmacy, CHU Dupuytren, Limoges, France
2 Biochemistry and Molecular Genetic Department, CHU Dupuytren, Limoges, France
3 EA6309 Myelinic Maintenance and Peripheral Neuropathies, Faculty of Medicine and Pharmacy, Limoges, France
Development of colored hydroalcoholic solutions of chlorhexidine for surgical field antisepsis: preparation process, antimicrobial and coloring efficiencies and stability study S. Filali , L.M. Tall, E. Diouf, D. Salmon, C. Pivot, F. Pirot Pharmacie, Hôpital Édouard Herriot, Lyon, France

Posters

Evaluation of the interest of automatisation in the management of cytotoxic production S. Perriat , H. Argueil, A. Martel, A. Fontan, C. Morel, Y. Cretu, F. Puisset, J-M. Canonge Institut Universitaire du Cancer de Toulouse - Oncopôle - 1 avenue Irène Joliot Curie 31100 Toulouse - France
Review of manual and automated compounding of intravenous drugs : an update in 2017 J-D. Hecq , C. Decoster, N. Leonard, C. Pirlot, L. Soumoy CHU UCL Namur, site Godinne, 1, avenue Therasse , 5530 Yvoir, Belgium
Implementation of a robot for the preparation of intravenous drugs in a pharmacy service L. Soumoy, C. Decoster, N. Leonard, C. Pirlot, J-D. Hecq CHU UCL Namur, site Godinne, 1, avenue Therasse , 5530 Yvoir, Belgium
Evaluation of the performance and ergonomics of the 4-way MediMix four-way pump L. Hachon , M. Moine, A. Martinet, M. Battistella, C. Mannechin,
N. Robert, D. Sankhare, J. Nicoulaud, I. Madelaine, N. Jourdan-Desrayaud
Pharmacy - Anticancer agents’ preparation unit, Saint-Louis Hospital, Greater Paris University Hospitals, Paris
Implementation of the DIANA® automaton for the preparation of dose banded chemotherapy in an isolator E. Goiffon , J. Bayle, R. Chevrier UPCO Centre Jean Perrin, Clermont-Ferrand, France
Automation of dose banded chemotherapy preparation : satisfaction survey on two automats E. Goiffon , J. Bayle, R. Chevrier UPCO Centre Jean Perrin, Clermont-Ferrand, France
DRUGCAM®’s performance in real-life production by simulation M. Laplace , B. Dalifard, B. Le Franc, M-A. Cadeac Service Pharmacie, Groupe Hospitalier de La Rochelle - Ré-Aunis, Rue du Docteur Schweitzer, 17000 La Rochelle Validation of the microbiological control of the parenteral nutrition bags by membrane filtration with the Equinox® pump by Millipore (steritest) and by direct seeding C. Louet 1, V. Blandeau1, M-E. Juvin2, S. Guernier1, F. Loton1, V. Lebreton1, E. Olivier1 1 Service de Pharmacotechnie, CHU Nantes Hôtel-Dieu, 1 Place Alexis Ricordeau, 44093 Nantes
2 Service de Bactériologie - Hygiène Hospitalière, CHU Nantes Hôtel-Dieu, 1 Place Alexis Ricordeau, 44093 Nantes
Comparison of two methods for microbiological control of isolator for reconstitution unit of cytotoxic drugs E. Lopez1, S. Toubal2, F. Clément2, B. Cortes1, L. Cadot1, D. Castel1 1 CH Ales-Cévennes, 811 Av. du Docteur Jean Goubert, 30100 Alès, France
2 CHU Montpellier, 371 Av. du Doyen Gaston Giraud, 34000 Montpellier, France
Survey of microbiological sampling practices in anticancer drugs preparation equipement M. Garcès , C. Devaux, F. Yav, N. Le Guyader Groupe Hospitalier Diaconesses-Croix Saint-Simon, 75020 Paris, France Microbiological monitoring of clean areas in healthcare establishments : trend analysis according to USP <1116> C. Nassar 1, A. Venet1, S. Crauste-Manciet1,2 1 Pharmaceutical Technology Department - University Hospital of Bordeaux (CHU de Bordeaux)
2 ARNA Laboratory, team ChemBioPharm, U1212 INSERM - UMR 5320 CNRS - Bordeaux University
Development of UV-Raman spectrometric analytical control applied to eyedrops hospital preparations E. Matusik , F. Smagghe, V. Gautier, S. Tombelle, T. Queruau Lamerie, F. Danicourt Pharmacie du Centre hospitalier de Dunkerque, 130 Avenue Louis Herbeaux, 59240 Dunkerque, France - elodie.matusik@gmail.com
Interest of UV-Raman spectrometry for the analytical control of solid hospital preparations : development for spironolactone capsules E. Matusik , F. Smagghe, V. Gautier, S. Tombelle, T. Queruau Lamerie, F. Danicourt Pharmacie du Centre hospitalier de Dunkerque, 130 Avenue Louis Herbeaux, 59240 Dunkerque, France - elodie.matusik@gmail.com Optimization of the qualitative parameters used for batch release of injectable anticancer drugs L.Tribaudeau 1, B. Raspaud1, A. Jourand1, S. Crauste-Manciet1,2 1 Pharmaceutical Technology Department, Bordeaux university hospital (CHU de Bordeaux), France
2 ARNA Laboratory-ChemBioPharm U1212 INSERM - UMR5320, CNRS - University of Bordeaux, France
Gravimetric control: accuracy, stability and performances in routine mode A. Rousselle 1, E. Bogart2, V. Dubreucq1, A. Villain1, S. Delbey1, I. Sakji1, F. Feutry1 1 Pharmacy, Oscar Lambret Center, 3th street Frédéric Combemale, 59000 Lille - France
2 Biostatistic, Oscar Lambret Center, 3th street Frédéric Combemale, 59000 Lille - France
A concept of biocontainment for GMP cell production applied in a public hospital L. Mustapha 1,2, J-M. Dubaele2, L. Waselle1, L. Tissot1, F. Sadeghipour3, J-F. Brunet1 1 Cell production center, Lausanne University Hospital, Chemin des Croisettes 22, 1066 Epalinges, Suisse
2 Pharmacie Centrale, Centre Hospitalier Universitaire, avenue Rene Laennec, 80054 Amiens, France
3 Service of Pharmacy, Lausanne University Hospital, Rue du Bugnon 46, 1000 Lausanne, Suisse
Manipulation of monoclonal antibodies: what impact on the health of manipulators and what organization to adopt? F. Smagghe , E. Matusik, V. Gauthier, S. Tombelle, F. Danicourt Centre Hospitalier de Dunkerque, 130 Avenue Louis Herbeaux, 59240 Dunkerque
Security FMECA as method to assess the exposure risk of healthcare worker to residual cytotoxic drug contaminations on workplace surfaces L. Lê1,2, D. Martinez1, P. Prognon1,2, E. Caudron1,2 1 Service Pharmacie, Hôpital européen Georges Pompidou, AP-HP, Paris, France
2 Lip(Sys)2, Chimie analytique pharmaceutique, Université Paris Sud, Paris Saclay, Chatenay-Malabry, France
Chemical contaminations in the centralized reconstitution units of cytotoxic drugs using isolators : benchmarking study in the Auvergne region S. Chaib 1, E. Goiffon1, S. Occhipinti1, H. Bertucat2, E. Deligeard3, I. Grange4, M. Jouannet-Romaszko5, M-P. Lafon6, E. Sigward7, R. Chevrier11 1 Centre Jean Perrin, Clermont-Ferrand, France
2 Centre hospitalier Jacques Lacarin, Vichy, France
3 Centre hospitalier Moulins Yzeure , Moulins, France
4 Centre hospitalier Emile Roux, Le Puy-en-Velay, France
5 Centre hospitalier universitaire de Clermont-Ferrand, Clermont-Ferrand, France
6 Centre Hospitalier Henri Mondor, Aurillac, Clermont-Ferrand, France
7 Centre Hospitalier de Montluçon, Montluçon, France
200.Stability study of 5 mg/ml pediatric prednisone oral suspension in Syrspend® A-C. Bonnaure , R. Bellay, P. Rault, M-A. Lester, P-N. Boivin Service de Pharmacie, CHU de Rennes, 2 rue Henri Le Guilloux, 35000 Rennes, France
Physico-chemical stability of noradrenaline bitartrate in polypropylene syringe for administration in the Intensive Care Unit B. Lardinois, J. Pector, Ch. Delcave, M, Godet, J. Jamart, B. Bihin, L. Soumoy, J-D. Hecq, L. Galanti Drug Stability Research Group, CHU UCL Namur, Yvoir, Belgique Physico-chemical stability of valproate sodium in polypropylene syringe for administration in the Intensive Care Unit B. Lardinois, A. Baltzis, M. Braibant, M. Godet, J. Jamart, B. Bihin, L. Soumoy, L. Galanti, J-D. Hecq Drug Stability Research Group, CHU UCL Namur, Yvoir, Belgique
Stability study of four vitamin formulations for parenteral nutrition in neonatology P. Rault1, B. Le Dare1, M. Ropert2, P-Y. Donnio3, S. Cammas-Marion1, P-N. Boivin1, M-A. Lester1 1 Pharmacy department, Rennes University Hospital, Rennes, France
2 Laboratory of biochemistry and toxicology, Rennes University Hospital, Rennes, France
3 Laboratory of bacteriology and hospital hygiene, Rennes University Hospital, Rennes, France
4 National School of Chemistry, Rennes, France
Stability of all-in-one parenteral nutrition admixtures containing Smoflipid® A. Thouvenin , M. Nouman, C. Jaskowiec, S. Poullain Pharmacy unit, Centre Hospitalier Intercommunal de Créteil, 40 avenue de Verdun 94000 Créteil Video tutorials: integration in the assurance quality system of the Pharmacotechny sector N. Duret-Aupy1, P. Breton2, M. Emonet2 1 CHU Angers, 4 Rue Larrey, 49100 Angers, service de Pharmacovigilance, France
2 CH Blois, Mail Pierre Charlot 41016 Blois, Pharmacie, France
Evaluation of the adaptability of a team of pharmaceutical assistants to an organisational change in the quality control of chemotherapy IV bags M. Bourhis , M. Friou, C. Giard, M. Bourquin-Lafay, I. Ferry, L. Escalup Institut Curie, Hôpital René Huguenin - 35 rue Dailly - 92210 Saint Cloud
Professionals practicing in healthcare settings and risks associated with exposure to antineoplastic drugs: developing training tools as part of a regional cancer network X. Gallois1, N. Fabié2, M. Giovanelli1 1 Pôle Pharmacie-Stérilisation - CHRU de Nancy - Hôpitaux de Brabois, Allée du Morvan, 54511 Vandœuvre-lès-Nancy, France
2 RRC ONCOLOR, 2 allée de Vincennes, 54500 Vandœuvre-lès-Nancy
Continuous training of pharmacy technicians: practical use of data from video monitoring of chemotherapy production M. Cardinaud , M. Laplace, B. Dalifard, M-A. Cadeac Pharmacy service, Groupe Hospitalier la Rochelle Ré-Aunis
1 rue du Dr Schweitzer, 17000 La Rochelle, France
Error simulation in a centralized cytotoxic unit M. Laffite, S. Biscarat, I. Grangé Centre Hospitalier Emile Roux, Service pharmacie,
12, Boulevard du Docteur Chantemesse, 43000 Le Puy-en-Velay, France
Controlled atmosphere area of errors: to learn otherwise J. Bellegarde1, R. Kimbidima1, R. Veillet1, S. Trevis1, V. Sautou2 1 CHU Clermont-Ferrand, Pôle Pharmacie, F-63003 Clermont-Ferrand, France
2 Université Clermont Auvergne, CHU Clermont Ferrand, CNRS, SIGMA Clermont,
ICCF, F-63000 Clermont-Ferrand, France
Implementation of fluorescein test in the initial and continuing training for pharmacy technicians at the oncology pharmacy at Brest Hospital N. Rioual, B. Rey-Rubio, C. Loeuillet, N. Mugnier, V. Cogulet Pharmacy, Brest Hospital, France
Issue of waste generated by chemotherapy at home - evaluation of the anti-flow device D. Regnault, E. Lheritier, M. Malherre, P. Rocatcher Pharmacie - Centre Hospitalier de Dieppe, France
Feasibility evaluation of 5Fluorouracil diffusers using by a filling pump E. Achain, T. Boileau, C. Sola, M. Coutinho, S. Pacher, Y. Cretu, S. Perriat, A. Martel,
F. Puisset, JM. Canonge
IUCT-Oncopole CHU de Toulouse, France
Impact of the anticipated preparation of portable diffusers on their diffusion rates C. Miguet, C. Leger, M. Delforge, A. Bove, K. Rouchette, M. Sabatier,
A. Bergougnoux, F. Puisset, J-M. Canonge
Institut Universitaire du Cancer de Toulouse - Oncopôle, 1 avenue Irène Joliot-Curie, 31100 Toulouse, France
Application of the FMECA method at the purchase/procurement process of chemotherapy drugs and devices: how to secure the steps? J. Saillard, A. Ferre, S. Sellin, C. Fronteau, P. Thomaré Oncologic Clinical Pharmacy Unit (UPCO), Nantes University Hospital Center, France
-risk analysis of an information system (SI) in the galenic preparations service M. Hamm2, A. Dory1, J. Bourbon1, F. Stalter2, M. Daubrosse2, F Reisz1, B. Gourieux1 1 Pharmacy Service
2 Hospital Informatization Service, Hôpitaux Universitaires de Strasbourg, France
Analysis of non-administered chemotherapy preparations (NCPs) wastage in 2015 and 2016 J. Santasouk, J. Bourbon, O. Kaatz, M. Ancel, JD. Kaiser, D. Roncalez Pharmacy and sterilization, L. Pasteur Hospital, 39 Av. de la liberté, 68024 Colmar-France
Risk assessment of hospital preparations according to the model proposed by the European Council Resolution CM / Res (2016) 1 E.H. Diouf1, M. Raynaud1, D. Salmon1,2, C. Merienne1, D. Laleye1, C. Pivot1, F. Pirot1,2 1 Pharmacie, Hôpital Édouard Herriot HCL, Lyon France
2 Laboratoire de Pharmacie Galénique Industrielle, UMR 5305, Université Lyon 1 France
Place of ready-to-use pockets of Gemcitabine in a unit of anti-cancer drugs preparations G. Herbin, E. Delbary, S. Join, G. Brunet, E. Kiep, C. Pobel Pharmacie CH de Saintonge, Saintes, France
Subcontracting of cytotoxic drug reconstitution : assessment and impact on our centralized unit after 5 months M. Bonsergent1, M. Bascoulergue1, V. Rasamijao2, B. Coret-Houbart1 1 Pharmacie, CHI Robert Ballanger, Aulnay-sous-Bois, France
2 Pharmacie, CH Saint Denis Delafontaine, Saint Denis, France
Pneumatic Transport System : what mechanical stress for our cytotoxic drugs? A. Villain, A. Rousselle, V. Dubreuq, S. Delbey, I. Sakji, F. Feutry Pharmacie, Centre Oscar Lambret, 3 Rue Frédéric Combemale, 59000 Lille, France New European resolutions and particle monitoring of high risk hospital preparations : moving towards GMP J. Martin, MA. Vonesch, F. Soudi, E.H. Diouf, C. Pivot, F. Pirot Pharmacie, Hôpital Édouard Herriot, Lyon
Is the preparation of Automated Doses Dispensing (ADD) impacted by tasks interruptions (TIs)? C. Aubineau, B. Rousset, S. Armand-Branger Centre de santé mentale angevin, France
Preparation of the administrated dose by repacking in dependent old people’s home (DOPH), still a relevant practice? V. Chawadronow, B. Martel, A. Landry, E. Peronne, S. Truet, D. Lemoine Centre hospitalier de Bayeux, 13 rue de Nesmond, 14400 Bayeux, France
Implementation of an electronic non-conformities management in a preparation unit of chemotherapies C. Lhermitte1, J. Daupin1, R. Ali Saoucha1, R. Rousseau1, E. Caudron1,2 1 Service Pharmacie, Hôpital européen Georges Pompidou, AP-HP, Paris, France
2 Lip(Sys)2, Chimie analytique pharmaceutique, Université Paris Sud, Paris Saclay, Chatenay-Malabry, France
Selection criterions for packaging of single-dose injectable solutions in ready-to-use syringes C. Brunel , L. Bourgue, E.H. Diouf, C. Merienne, D. Salmon, C. Pivot, F. Pirot Groupement Hospitalier Centre - Hôpital Edouard Herriot - Pharmacie à usage intérieur (PUI)
Unité Préparation et Contrôle du Médicament - Lyon, France
Analysis of the time devoted to the circuit of hospital preparations for anticancer agents L. Hachon , M. Moine, A. Martinet, N. Robert, D. Sankhare, J. Nicoulaud,
I. Madelaine, N. Jourdan-Desrayaud
Pharmacy - Anticancer agents’ preparation unit, Saint-Louis Hospital, Greater Paris University Hospitals, Paris
Management of Advanced Therapy Medicinal Products (ATMP) in hospitals: circuits considered at the University Hospital of Lille M. Pinturaud1, C. Nassar1, M. Vasseur1, P. Odou1,2 1 CHU Lille, Institut de Pharmacie, 59000 Lille, France
2 Université de Lille, EA 7365 - GRITA - 59000 Lille, France
Opening a parenteral compounding facility … A Challenge ! D. Fremont, E. Guerriero, M. Dermu, V. Massot, T. Storme Secteur Pharmacotechnie - Service de Pharmacie - Hôpital Universitaire Mère-Enfant Robert Debré
Assistance Publique - Hôpitaux de Paris - 48 Bld Sérurier Paris 19ème, France

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